Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Laura Lückemann"'
Autor:
Marie Jakobs, Lisa Trautmann, Martin Hadamitzky, Julia Bihorac, Lucie Jacquet, Uwe Christians, Björn Schniedewind, Laura Lückemann, Manfred Schedlowski
Publikováno v:
Brain and Behavior, Vol 14, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Background Studies in experimental animals revealed that acute and chronic treatment with small‐molecule immunosuppressive drugs lead to neurobehavioral alterations in rodents. Methods Against this background, this study investigated behav
Externí odkaz:
https://doaj.org/article/28f1dd53d1d94753b409d9905b667ea4
Autor:
Susann Hetze, Lennart Barthel, Laura Lückemann, Hauke S. Günther, Clemens Wülfing, Yasmin Salem, Marie Jakobs, Tina Hörbelt-Grünheidt, Jasmin Petschulat, Ivo Bendix, Ulrike Weber-Stadlbauer, Ulrich Sure, Manfred Schedlowski, Martin Hadamitzky
Publikováno v:
Brain, Behavior, and Immunity. 106:270-279
Mechanistic target of rapamycin (mTOR)-signaling is one key driver of glioblastoma (GBM), facilitating tumor growth by promoting the shift to an anti-inflammatory, pro-cancerogenic microenvironment. Even though mTOR inhibitors such as rapamycin (RAPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0cbcb32918566a350769d0e2923c68
https://doi.org/10.1016/j.bbi.2022.09.006
https://doi.org/10.1016/j.bbi.2022.09.006
Publikováno v:
Current protocolsLiterature Cited. 2(10)
The pharmacological effects of an immunosuppressive drug, such as cyclosporine A (CsA), can be learned and retrieved by humans and animals when applying associative learning paradigms. This principle is based on Pavlovian conditioning, in which repea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d6afd1f405255210a4006b668d126e
https://pubmed.ncbi.nlm.nih.gov/36219717
https://pubmed.ncbi.nlm.nih.gov/36219717
Autor:
Laura Lückemann, Ivo Bendix, Tina Hörbelt, Mathis Richter, Jan Brosda, Marie Jakobs, Manfred Schedlowski, Martin Hadamitzky, Thorsten M. Becker
Publikováno v:
Psychopharmacology
Rationale Calcineurin is a protein regulating cytokine expression in T lymphocytes and calcineurin inhibitors such as cyclosporine A (CsA) are widely used for immunosuppressive therapy. It also plays a functional role in distinct neuronal processes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec152ad184eea14ab6a38fdebbf8562c
https://doi.org/10.1007/s00213-020-05751-1
https://doi.org/10.1007/s00213-020-05751-1
Publikováno v:
Neuroforum. 26:179-184
Experimental studies in rodents and humans have convincingly demonstrated that immune functions can be modulated by associative learning processes. We have established a conditioned taste avoidance (CTA) paradigm in rats by pairing a novel taste (con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d5494643f9d011b7b295a66232de50
https://doi.org/10.1515/nf-2020-0017
https://doi.org/10.1515/nf-2020-0017
Autor:
Laura Lückemann, Susann Hetze, Tina Hörbelt, Martin Hadamitzky, Marie Jakobs, Manfred Schedlowski
Publikováno v:
Brain, behavior, and immunity. 95
Peripheral immune responses can be modulated by taste-immune associative learning where the presentation of a sweet taste as conditioned stimulus (CS) is paired with the injection of an immunosuppressive substance as unconditioned stimulus (US). Prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6631f000fc53474a0046be6dc389f5d6
https://pubmed.ncbi.nlm.nih.gov/33691148
https://pubmed.ncbi.nlm.nih.gov/33691148
Die gelernte Placeboantwort im Immunsystem basiert auf der wechselseitigen Interaktion zwischen Gehirn und Immunsystem; beide Systeme tauschen uber humorale und neuronale Kommunikationswege bestandig Informationen aus. Basierend auf diesem Kommunikat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc7344e6d6a70bc3e425bd753cddb51
https://www.ncbi.nlm.nih.gov/pubmed/32642946
https://www.ncbi.nlm.nih.gov/pubmed/32642946
OBJECTIVE Patients with chronic inflammatory autoimmune diseases benefit from a broad spectrum of immunosuppressive and antiproliferative medication available today. However, nearly all of these therapeutic compounds have unwanted toxic side effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b41341444c95d5fe7f973d35d6da376
https://www.ncbi.nlm.nih.gov/pubmed/31509354
https://www.ncbi.nlm.nih.gov/pubmed/31509354
The phenomenon of behaviorally conditioned immunological and neuroendocrine functions has been investigated for the past 100 yr. The observation that associative learning processes can modify peripheral immune functions was first reported and investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0382bbdf93a4350062ad4ead44b840a
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85071923633
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85071923633
Autor:
Laura Lückemann, Matthew J Haight, Julia Kirchhof, Arne Herring, Ivo Bendix, Manfred Schedlowski, Kathy Keyvani, Meike Unteroberdörster, Martin Hadamitzky
Publikováno v:
International Journal of Neuropsychopharmacology
Background: Clinical data indicate that therapy with small-molecule immunosuppressive drugs is frequently accompanied by an incidence rate of neuropsychiatric symptoms. In the current approach, we investigated in rats whether repeated administration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda96105349451df64dbc32435d2fd3f
http://europepmc.org/articles/PMC6007742
http://europepmc.org/articles/PMC6007742