Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laura López-Molina"'
Autor:
Laura López-Molina, Anna Sancho-Balsells, Omar Al-Massadi, Enrica Montalban, Jordi Alberch, Belén Arranz, Jean-Antoine Girault, Albert Giralt
Publikováno v:
Neurobiology of Disease, Vol 194, Iss , Pp 106487- (2024)
Pyk2 has been shown previously to be involved in several psychological and cognitive alterations related to stress, Huntington's disease, and Alzheimer's disease. All these disorders are accompanied by different types of impairments in sociability, w
Externí odkaz:
https://doaj.org/article/247d3641159b40289b2f850753945ccc
Autor:
Ened Rodríguez-Urgellés, Anna Sancho-Balsells, Wanqi Chen, Laura López-Molina, Ivan Ballasch, Ignacio del Castillo, Conxita Avila, Jordi Alberch, Albert Giralt
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Glycogen synthase kinase 3β (GSK3β) is a core protein, with a relevant role in many neurodegenerative disorders including Alzheimer’s disease. The enzyme has been largely studied as a potential therapeutic target for several neurological diseases
Externí odkaz:
https://doaj.org/article/d60990af8ded45d1b95ff150c2ee6b91
Autor:
Laura López-Molina, Joaquín Fernández-Irigoyen, Carmen Cifuentes-Díaz, Jordi Alberch, Jean-Antoine Girault, Enrique Santamaría, Silvia Ginés, Albert Giralt
Publikováno v:
Cells, Vol 11, Iss 5, p 842 (2022)
Pyk2 is a non-receptor tyrosine kinase enriched in hippocampal neurons, which can be activated by calcium-dependent mechanisms. In neurons, Pyk2 is mostly localised in the cytosol and dendritic shafts but can translocate to spines and/or to the nucle
Externí odkaz:
https://doaj.org/article/0a7c1dc8dcf64ea6931ba2d5001a74b4
Autor:
Marc Espina, Laura López-Molina, Anika Pupak, Nadia Di Franco, Verónica Brito, Juan Carlos Arévalo, Sílvia Ginés
Publikováno v:
A: Pathogenic mechanisms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aa9b7902c805b2f6f10b15e0d5c6261
https://doi.org/10.1136/jnnp-2022-ehdn.21
https://doi.org/10.1136/jnnp-2022-ehdn.21
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Neurobiology of Disease, Vol 136, Iss, Pp 104741-(2020)
Universidad de Barcelona
Neurobiology of Disease, Vol 136, Iss, Pp 104741-(2020)
Mitochondria-associated membranes (MAMs) are dynamic structures that communicate endoplasmic reticulum (ER) and mitochondria allowing calcium transfer between these two organelles. Since calcium dysregulation is an important hallmark of several neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323f6b66331e95c0a5e15b5bf285ab14
http://hdl.handle.net/2445/172078
http://hdl.handle.net/2445/172078
Autor:
Anna Sancho-Balsells, Jordi Alberch, Carmen Cifuentes-Diaz, Agnès Gruart, Silvia Ginés, Jean-Antoine Girault, Benoit de Pins, Ana M. López, Enrica Montalban, Albert Giralt, Amel Thamila Farah, Laura López-Molina, José M. Delgado-García
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
It has been well documented that neurotrophins, including brain-derived neurotrophic factor (BDNF), are severely affected in Alzheimer's disease (AD), but their administration faces a myriad of technical challenges. Here we took advantage of the earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66df69a32c1f60ae582590f46b97a861
http://hdl.handle.net/2445/160697
http://hdl.handle.net/2445/160697
Autor:
Marion Tible, Stefan T. Arold, Jean-Antoine Girault, Carmen Cifuentes-Diaz, Albert Giralt, Vincent Deramecourt, Laura López-Molina, Silvia Ginés, Benoit de Pins, Amel Thamila Farah, Jacques Hugon
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Pyk2 is a Ca2+-activated non-receptor tyrosine kinase enriched in forebrain neurons and involved in synaptic regulation. Human genetic studies associated PTK2B, the gene coding Pyk2, with risk for Alzheimer's disease (AD). We previously showed that P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e96e12e44f7a9d4d4153dfa104cca07
http://hdl.handle.net/2445/143968
http://hdl.handle.net/2445/143968
The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice
Autor:
Marc Espina, Nadia Di Franco, Martina Brañas-Navarro, Irene Rodriguez Navarro, Veronica Brito, Laura Lopez-Molina, Carlos Costas-Insua, Manuel Guzmán, Silvia Ginés
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106225- (2023)
Increasing evidence indicates that a key factor in neurodegenerative diseases is the activation of the unfolded protein response (UPR) caused by an accumulation of misfolded proteins in the endoplasmic reticulum (ER stress). Particularly, in Huntingt
Externí odkaz:
https://doaj.org/article/ede8d1825f004ae789741daebb76f3ed
Publikováno v:
Neurobiology of Disease, Vol 136, Iss , Pp 104741- (2020)
Mitochondria-associated membranes (MAMs) are dynamic structures that communicate endoplasmic reticulum (ER) and mitochondria allowing calcium transfer between these two organelles. Since calcium dysregulation is an important hallmark of several neuro
Externí odkaz:
https://doaj.org/article/447b8eee8c6a4dc58f2c1bb4d720e0ea