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pro vyhledávání: '"Laura Klewer"'
Autor:
Yao-Wen Wu, Laura Klewer
Publikováno v:
Chemistry – A European Journal
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry (Weinheim an Der Bergstrasse, Germany)
Light‐inducible approaches provide a means to control biological systems with spatial and temporal resolution that is unmatched by traditional genetic perturbations. Recent developments of optogenetic and chemo‐optogenetic systems for induced pro
Autor:
Ingrid R. Vetter, Dale Corkery, Luca Laraia, Nelli Erwin, Herbert Waldmann, Maja Köhn, Pablo Rios-Munoz, Roland Winter, Mridula Dwivedi, Walter Hofer, Lei Li, Yao-Wen Wu, Malte Metz, Beate Schölermann, Andreas Brockmeyer, Laura Klewer, Alexandra Friese, Petra Janning, Hacer Karatas, Georgios Konstantinidis, Slava Ziegler
Publikováno v:
Nature Chemical Biology
Laraia, L, Friese, A, Corkery, D P, Konstantinidis, G, Erwin, N, Hofer, W, Karatas, H, Klewer, L, Brockmeyer, A, Metz, M, Schölermann, B, Dwivedi, M, Li, L, Rios-Munoz, P, Köhn, M, Winter, R, Vetter, I R, Ziegler, S, Janning, P, Wu, Y W & Waldmann, H 2019, ' The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis ', Nature Chemical Biology, vol. 15, no. 7, pp. 710-720 . https://doi.org/10.1038/s41589-019-0307-5
Laraia, L, Friese, A, Corkery, D P, Konstantinidis, G, Erwin, N, Hofer, W, Karatas, H, Klewer, L, Brockmeyer, A, Metz, M, Schölermann, B, Dwivedi, M, Li, L, Rios-Munoz, P, Köhn, M, Winter, R, Vetter, I R, Ziegler, S, Janning, P, Wu, Y W & Waldmann, H 2019, ' The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis ', Nature Chemical Biology, vol. 15, no. 7, pp. 710-720 . https://doi.org/10.1038/s41589-019-0307-5
Autophagy mediates the degradation of damaged proteins, organelles and pathogens, and plays a key role in health and disease. Thus, the identification of new mechanisms involved in the regulation of autophagy is of major interest. In particular, litt
Autor:
Yao-Wen Wu, Laura Klewer
Publikováno v:
Chemistry – A European Journal. 25
Publikováno v:
Current Opinion in Chemical Biology. 28:194-201
Small-molecule perturbation of biological systems is able to tackle biological problems that are not accessible by classical genetic interference methods. Chemically induced dimerization (CID) has been used as a valuable tool to study various biologi