Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Laura K. Johnston"'
Autor:
Paul J. Bryce, Laura K. Johnston
Publikováno v:
Frontiers in Medicine, Vol 4 (2017)
Over the last decade, significant interest in the contribution of three “epithelial-derived cytokines,” such as thymic stromal lymphopoietin, interleukin 25, and interleukin 33 (IL-33), has developed. These cytokines have been strongly linked to
Externí odkaz:
https://doaj.org/article/8879bd9d2bc74dc9a2282dd70f184614
Autor:
Andy Chao Hsuan Lee, Arianna Edobor, Thirushan Wigakumar, Maria Lysandrou, Laura K. Johnston, Phillip McMullen, Vikranth Mirle, Ashley Diaz, Ryan Piech, Rebecca Rose, Martin Jendrisak, Diego di Sabato, Kumaran Shanmugarajah, John Fung, Jessica Donington, Maria Lucia Madariaga
Publikováno v:
Clinical transplantation. 36(7)
Ex vivo lung perfusion (EVLP) is used to assess and preserve lungs prior to transplantation. However, its inherent immunomodulatory effects are not completely understood. We examine perfusate and tissue compartments to determine the change in immune
Autor:
Sam J. Small, Katherine R Pilkington, Kylie M. Price, Joanne Lannigan, Maria C. Jaimes, Laura K Johnston, Brittany Lewer, Laura Ferrer-Font, Lily M. Park
Publikováno v:
Current protocolsLiterature Cited. 1(9)
Technological advancements in fluorescence flow cytometry and an ever-expanding understanding of the complexity of the immune system have led to the development of large flow cytometry panels reaching up to 43 colors at the single-cell level. However
Autor:
Chia-Lin Hsu, Sergejs Berdnikovs, Rebecca A. Krier-Burris, Karen B. Chien, Andrew N. J. McKenzie, Paul J. Bryce, Krishan D. Chhiba, Laura K. Johnston
Publikováno v:
The Journal of Immunology. 197:3445-3453
Eosinophils are important in the pathogenesis of many diseases, including asthma, eosinophilic esophagitis, and eczema. Whereas IL-5 is crucial for supporting mature eosinophils (EoMs), the signals that support earlier eosinophil lineage events are l
Autor:
Steven F. Ziegler, Paul J. Bryce, Laura K. Johnston, Hongwei Han, Florence Roan, Dirk E. Smith
Publikováno v:
Mucosal immunology
Atopic dermatitis (AD) often precedes asthma and food allergy, indicating that epicutaneous sensitization to allergens may be important in the induction of allergic responses at other barrier surfaces. Thymic stromal lymphopoietin (TSLP) and IL-33 ar
Autor:
Laura K. Johnston, Paul J. Bryce
Publikováno v:
Frontiers in Medicine
Frontiers in Medicine, Vol 4 (2017)
Frontiers in Medicine, Vol 4 (2017)
Over the last decade, significant interest in the contribution of three “epithelial-derived cytokines,” thymic stromal lymphopoietin (TSLP), Interleukin 25 (IL-25), and Interleukin 33 (IL-33) has developed. These cytokines have been strongly link
Publikováno v:
The Journal of Immunology. 192:2529-2534
Food allergies represent an increasingly prevalent human health problem, and therapeutic options remain limited, with avoidance being mainstay, despite its adverse effects on quality of life. A better understanding of the key immunological mechanisms
Autor:
William C. Parks, Isham Huizar, Sina A. Gharib, Josiah F. Hanson, Timothy P. Birkland, Laura K. Johnston, Anne M. Manicone, Ying Wang
Publikováno v:
Journal of Leukocyte Biology. 95:9-18
Members of the MMP family function in various processes of innate immunity, particularly in controlling important steps in leukocyte trafficking and activation. MMP28 (epilysin) is a member of this family of proteinases, and we have found that MMP28
Publikováno v:
The Journal of Immunology. 190:5731-5738
TGF-β1 is an important suppressive mediator of inflammation, but it can also drive fibrosis and remodeling in the lung. In response to intratracheal LPS, neutrophils migrate into the lung, and TGF-β1 was suggested to protect against the ensuing inj
Publikováno v:
Respiratory Research
Background There are pulmonary consequences to obesity, including increased prevalence of asthma, greater susceptibility to influenza, and possibly reduced susceptibility to lung injury. Although it is well established that obesity is associated with