Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Laura K. Esser"'
Autor:
Laura K. Esser, Vittorio Branchi, Sonia Leonardelli, Natalie Pelusi, Adrian G. Simon, Niklas Klümper, Jörg Ellinger, Stefan Hauser, Maria A. Gonzalez-Carmona, Manuel Ritter, Glen Kristiansen, Hubert Schorle, Michael Hölzel, Marieta I. Toma
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Clear cell renal cell carcinoma (ccRCC) is the most common renal cancer accounting for 80% of all renal cancers as well as the majority of renal cancer-associated deaths. During the last decade, the treatment paradigm for ccRCC has radically changed.
Externí odkaz:
https://doaj.org/article/97d1d568f6ac4813aad29aec50665885
Publikováno v:
Molecular Cancer Therapeutics. 18:B087-B087
PARK2 is an E3-ubiquitin-ligase, which plays an important role in mitophagy, a macroautophagy process that selectively degrades defective mitochondria. The significant downregulation of mRNA and protein levels in clear cell renal cell carcinoma (ccRC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c69026313f8caae8df2349ad5c46c51
https://doi.org/10.1158/1535-7163.targ-19-b087
https://doi.org/10.1158/1535-7163.targ-19-b087