Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Laura K, Fonken"'
Autor:
Kevin Sanchez, Sienna L. Wu, Reha Kakkar, Jeffrey S. Darling, Claire S. Harper, Laura K. Fonken
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 30, Iss , Pp 100638- (2023)
Estrogens are a group of steroid hormones that promote the development and maintenance of the female reproductive system and secondary sex characteristics. Estrogens also modulate immune responses; estrogen loss at menopause increases the risk of inf
Externí odkaz:
https://doaj.org/article/01a2f6c964784f2cb9df8a16e2c42cc4
Autor:
Kevin Sanchez, Jeffrey S. Darling, Reha Kakkar, Sienna L. Wu, Andrew Zentay, Christopher A. Lowry, Laura K. Fonken
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Aging and reduced exposure to environmental microbes can both potentiate neuroinflammatory responses. Prior studies indicate that immunization with the immunoregulatory and anti-inflammatory bacterium, Mycobacterium vaccae (M. vaccae), in ag
Externí odkaz:
https://doaj.org/article/2d8e2d3fc26e4a73a4b71f557848e50d
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 17, Iss , Pp 100337- (2021)
Altered working and sleeping schedules during the COVID-19 pandemic likely impact our circadian systems. At the molecular level, clock genes form feedback inhibition loops that control 24-hr oscillations throughout the body. Importantly, core clock g
Externí odkaz:
https://doaj.org/article/a02846bc084f4c14a2cac7f76dd6f630
Publikováno v:
Alcohol. 107:153-167
As the percentage of the global population over age 65 grows, and with it a subpopulation of individuals with alcohol use disorder (AUD), understanding the effect of alcohol on the aged brain is of utmost importance. Neuroinflammation is implicated i
Autor:
James E, Hassell, Michael V, Baratta, Isabella P, Fallon, Philip H, Siebler, Bree L, Karns, Kadi T, Nguyen, Chloé A, Gates, Laura K, Fonken, Matthew G, Frank, Steven F, Maier, Christopher A, Lowry
Publikováno v:
Brain, Behavior, and Immunity. 107:1-15
Stress-related psychiatric disorders including anxiety disorders, mood disorders, and trauma and stressor-related disorders, such as posttraumatic stress disorder (PTSD), affect millions of people world-wide each year. Individuals with stress-related
Publikováno v:
Experimental Neurology. 364:114382
Spinal cord injury (SCI) predisposes individuals to anxiety and chronic pain. Anxiety- and pain-like behavior after SCI can be tested in rodents, yet commonly used tests assess one variable and may not replicate effects of SCI or sex differences seen
Autor:
Brandon M. Marquart, Mathew R. Arnold, Noah Fierer, Kristin E. Cler, Laura K. Fonken, Steven F. Maier, Kelsey M. Loupy, Cristian A. Zambrano, Ahmed I. Elsayed, Tumim W. Yifru, Heather M. D'Angelo, Matthew G. Frank, Christopher A. Lowry, Matthew J. Gebert
Publikováno v:
Brain Behav Immun
Stress-related disorders, such as posttraumatic stress disorder (PTSD), are highly prevalent and often difficult to treat. In rodents, stress-related, anxiety-like defensive behavioral responses may be characterized by social avoidance, exacerbated i
Publikováno v:
Brain Behav Immun
Prior exposure to acute and chronic stressors potentiates the neuroinflammatory and microglial pro-inflammatory response to subsequent immune challenges suggesting that stressors sensitize or prime microglia. Stress-induced priming of the NLRP3 infla
Autor:
Jacob R. Bumgarner, Zachary M. Weil, Randy J. Nelson, William H. Walker, O. Hecmarie Meléndez-Fernández, Ning Zhang, A. Courtney DeVries, Jennifer A. Liu, Laura K. Fonken
Publikováno v:
Eur J Neurosci
Circadian rhythms are endogenous biological cycles that synchronize physiology and behaviour to promote optimal function. These ~24-hr internal rhythms are set to precisely 24 hr daily by exposure to the sun. However, the prevalence of night-time lig
Autor:
Laura K. Fonken, Madeleine F. Dwortz, Tyler M. Milewski, Frances A. Champagne, Andrew D. Gaudet, James P. Curley, Rebecca L. Young, Won Hee Lee
Social status is a critical factor determining health outcomes in human and nonhuman social species. In social hierarchies with reproductive skew, individuals compete to monopolize resources and increase mating opportunities. This can come at a signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::551cfd9ce463729172e1cbe7b475e7df
https://doi.org/10.1101/2021.09.04.458987
https://doi.org/10.1101/2021.09.04.458987