Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Laura K, Fogli"'
Autor:
Nirali Shah, Lili Yang, Kasia Bourcier, Antoni Ribas, Pawel Kalinski, Ke Liu, Phil Greenberg, Carl June, Marcela Maus, Steven Rosenberg, Madhav Dhodapkar, Irina Tiper, Chantale Bernatchez, Michael Hudecek, Stanley Riddell, Stephen Gottschalk, Crystal Mackall, Lisa Butterfield, Greg Delgoffe, Michael Nishimura, Terry Fry, Marc S. Ernstoff, Christopher Klebanoff, Elad Sharon, Malcolm Brenner, Cliona Rooney, Christine Brown, Marc S Ernstoff, Tonya Webb, Magdalena Thurin, Wendell Lim, David Stroncek, Catherine Bollard, Helen Chen, Cameron Turtle, Christian Hinrichs, Laura K Fogli, Rosemarie Aurigemma, Connie L Sommers, Steven Albelda, Renier Brentjens, Yvonne Chen, Laronna Colbert, Kenneth Cornetta, Jason Cristofaro, Thomas Finn, Laura K Fogli Hunter, Alyssa Galaro, Ananda Goldrath, Ray Harris, Lori Henderson, Yuxia Jia, Dan Kaufman, Bruce Levine, Lawrence Lum, Samantha Maragh, Alex Marson, Raj Puri, Jake Reder, Isabelle Riviere, Kole Roybal, Rachelle Salomon, Tal Salz, Barbra Sasu, Andrea Schietinger, Connie L. Sommers, Minkyung Song, Fyodor Urnov, Anthony Welch, Travis Young, Jason Yovandich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Cell-based immunotherapies have had remarkable success in the clinic, specifically in the treatment of hematologic malignancies. However, these strategies have had limited efficacy in patients with solid tumors. To better understand the challenges in
Externí odkaz:
https://doaj.org/article/f4500c9773db47d7abfb74eccac2d857
Autor:
James H. Doroshow, Richard Simon, Beverly A. Teicher, Annamaria Rapisarda, John W. Connelly, Xiaolin Wu, Erik Harris, Ming-Chung Li, Andrea Regier Voth, Melanie A. Simpson, Sarah B. Miller, Mariam M. Konaté, Laura K. Fogli, Eric C. Polley, Alida Palmisano, Dmitriy Sonkin, Jianwen Fang, Julia Krushkal, Hossein Hamed, Curtis Hose, Yingdong Zhao, Anne Monks
This file contains Supplementary Figure S1 (Correlation between downregulation of EGFR transcriptional target genes, and sensitivity to erlotinib at the high concentration after 6 hours); Supplementary Figure S2 (EGFR inhibitor and DNA damaging agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc993771930d8a7ddbff3301672bc8f
https://doi.org/10.1158/0008-5472.22419693.v1
https://doi.org/10.1158/0008-5472.22419693.v1
Autor:
James H. Doroshow, Richard Simon, Beverly A. Teicher, Annamaria Rapisarda, John W. Connelly, Xiaolin Wu, Erik Harris, Ming-Chung Li, Andrea Regier Voth, Melanie A. Simpson, Sarah B. Miller, Mariam M. Konaté, Laura K. Fogli, Eric C. Polley, Alida Palmisano, Dmitriy Sonkin, Jianwen Fang, Julia Krushkal, Hossein Hamed, Curtis Hose, Yingdong Zhao, Anne Monks
The intracellular effects and overall efficacies of anticancer therapies can vary significantly by tumor type. To identify patterns of drug-induced gene modulation that occur in different cancer cell types, we measured gene-expression changes across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c547975162ffcae835aa494f5df13e
https://doi.org/10.1158/0008-5472.c.6510450
https://doi.org/10.1158/0008-5472.c.6510450
Autor:
Jiuping Ji, Yiping Zhang, Christophe E Redon, William C Reinhold, Alice P Chen, Laura K Fogli, Susan L Holbeck, Ralph E Parchment, Melinda Hollingshead, Joseph E Tomaszewski, Quentin Dudon, Yves Pommier, James H Doroshow, William M Bonner
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171582 (2017)
Phosphorylated H2AX (γ-H2AX) is a sensitive marker for DNA double-strand breaks (DSBs), but the variability of H2AX expression in different cell and tissue types makes it difficult to interpret the meaning of the γ-H2AX level. Furthermore, the assa
Externí odkaz:
https://doaj.org/article/c5271db0c4334b48803bddf775b6a904
Autor:
Laura K. Fogli, Geraldine O'Sullivan Coyne, William R. Schelman, Richard D. Kim, Nancy Moore, Bassel F. El-Rayes, Chandra P. Belani, Naoko Takebe, Heinz-Josef Lenz, James H. Doroshow, Cindy L. O'Bryant, Sanjay Goel, Jan H. Beumer, Alice P. Chen, Larry Rubinstein, Richard Piekarz, Brian F. Kiesel, Afshin Dowlati, Vincent Chung, Shivaani Kummar, Ulka N. Vaishampayan, Joseph Tuscano
Publikováno v:
British Journal of Clinical Pharmacology
Aims The histone deacetylase inhibitor belinostat has activity in various cancers. Because belinostat is metabolized by the liver, reduced hepatic clearance could lead to excessive drug accumulation and increased toxicity. Safety data in patients wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da699f2f14408ad5cd5706ebb3ca7d05
http://europepmc.org/articles/PMC6848909
http://europepmc.org/articles/PMC6848909
Autor:
Jared C. Foster, Geraldine O'Sullivan Coyne, Naoko Takebe, Kristin Fino, Elad Sharon, James H. Doroshow, Ralph E. Parchment, Laura K Fogli, Alice P. Chen, Katherine V. Ferry-Galow, Suzanne George, James S. Hu, Anthony P. Conley, Richard F. Riedel, Melissa Amber Burgess, Nancy Moore, John Glod, Abdul Rafeh Naqash, Brian A. Van Tine, William L. Read
Publikováno v:
Journal of Clinical Oncology. 39:11519-11519
11519 Background: ASPS constitutes < 1% of soft tissue sarcomas and frequently presents in adolescents and young adults. There are no approved therapies for ASPS. We are currently evaluating the clinical activity of atezolizumab (atezo), an anti-PD-L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b29911b19c7d813f752069641fd0a9f2
https://doi.org/10.1200/jco.2021.39.15_suppl.11519
https://doi.org/10.1200/jco.2021.39.15_suppl.11519
Autor:
Aranzazu Mediero-Munoz, Bruce N. Cronstein, Carmen Corciulo, Shahla Abdollahi, Laura K Fogli, Sergei B. Koralov, Lu Yang, Melania H Fanok, Jose U. Scher
Objective To introduce a novel preclinical animal model of psoriatic arthritis (PsA) in R26Stat3Cstopfl/fl CD4Cre mice, and to investigate the role of Th17 cytokines in the disease pathogenesis. Methods We characterized a novel murine model of Th17-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3365c60fa30081212db77ea566e373
https://europepmc.org/articles/PMC5984671/
https://europepmc.org/articles/PMC5984671/
Autor:
Eric C. Polley, Mariam M. Konaté, Hossein A. Hamed, Yingdong Zhao, Dmitriy Sonkin, James H. Doroshow, Erik Harris, Richard Simon, John Connelly, Anne Monks, Beverly A. Teicher, Melanie A. Simpson, Alida Palmisano, Laura K. Fogli, Ming Chung Li, Jianwen Fang, Curtis Hose, Annamaria Rapisarda, Andrea Regier Voth, Sarah B. Miller, Xiaolin Wu, Julia Krushkal
Publikováno v:
Cancer research. 78(24)
The intracellular effects and overall efficacies of anticancer therapies can vary significantly by tumor type. To identify patterns of drug-induced gene modulation that occur in different cancer cell types, we measured gene-expression changes across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f8bb6876638f4383afc133f4d4b7c5
https://pubmed.ncbi.nlm.nih.gov/30355619
https://pubmed.ncbi.nlm.nih.gov/30355619
Autor:
Stefano Pileri, Pier Luigi Zinzani, Christine McIntosh, Luigi Scotto, Jennifer E Amengual, Enrica Marchi, Kelly Zullo, Matko Kalac, Fabio Fuligni, Pier Paolo Piccaluga, Laura K Fogli, Maura Rossi, Owen A. O'Connor, Danielle C Bongero
Publikováno v:
British Journal of Haematology. 171:215-226
Summary T-cell lymphomas (TCL) are aggressive lymphomas usually treated with CHOP (cyclophsophamide, doxorubicin, vincristine, prednisolone)-like regimens upfront. Recent data suggest that TCL are driven by epigenetic defects, potentially rendering t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce0ca4b0adfe261c3472964823ebaa6
https://doi.org/10.1111/bjh.13566
https://doi.org/10.1111/bjh.13566
Autor:
Laura K Fogli, Jo Ann Latkowski, Adriana Heguy, Swati Goel, Cynthia Liu, Miriam Eckstein, Jeff Kutok, Sergei B. Koralov, Amy Sun, Mark S. Sundrud, Charalampos Lazaris, Rodrigo S. Lacruz, Niels Ødum, Vijay Narendran, Iannis Aifantis, Melania H Fanok, Igor Dolgalev, Kasthuri Kannan, Mary E. Laird, Kenneth B. Hymes
Publikováno v:
The Journal of investigative dermatology. 138(5)
Cutaneous T-cell lymphoma is a heterogeneous group of lymphomas characterized by the accumulation of malignant T cells in the skin. The molecular and cellular etiology of this malignancy remains enigmatic, and what role antigenic stimulation plays in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d415e920ea2b63e463bf738ea49573
https://pubmed.ncbi.nlm.nih.gov/29681389
https://pubmed.ncbi.nlm.nih.gov/29681389