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Autor:
Seetharama A. Acharya, Joel M. Friedman, Eric S. Peterson, Belur N. Manjula, Imran Khan, Celia Bonaventura, Laura Juczszak, Jiaqian Wang, Roman Shinder
Publikováno v:
Biochemistry. 43:4832-4843
The water-filled central cavity of human adult hemoglobin (Hb A) is the binding or interaction site for many different allosteric effectors. Oxygen binding titrations reveal that pyrenetetrasulfonate (PyTS), a fluorescent analogue of 2,3-diphosphogly