Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Laura Jiménez-Sánchez"'
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 16 (2024)
Externí odkaz:
https://doaj.org/article/9be64184174c43919bdc556aef3e26c9
Autor:
Héctor Vázquez-Lorente, Lourdes Herrera-Quintana, Laura Jiménez-Sánchez, Beatriz Fernández-Perea, Julio Plaza-Diaz
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 996 (2024)
Evidence is increasing that vitamin D and CYP11A1-derived vitamin D, tachysterol, and lumisterol metabolites play a significant antioxidant role beyond its classical functions in bone health and calcium metabolism. Several recent studies have linked
Externí odkaz:
https://doaj.org/article/2a55c32910af4bbcb9c514f8f1daebff
Autor:
Pilar González-García, María Elena Díaz-Casado, Agustín Hidalgo-Gutiérrez, Laura Jiménez-Sánchez, Mohammed Bakkali, Eliana Barriocanal-Casado, Germaine Escames, Riccardo Zenezini Chiozzi, Franziska Völlmy, Esther A. Zaal, Celia R. Berkers, Albert J.R. Heck, Luis C. López
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102403- (2022)
Defects in Coenzyme Q (CoQ) metabolism have been associated with primary mitochondrial disorders, neurodegenerative diseases and metabolic conditions. The consequences of CoQ deficiency have not been fully addressed, and effective treatment remains c
Externí odkaz:
https://doaj.org/article/a2808f9af5f749cfa28f555ecb1b8d8d
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/2e63f743a6ba473aa26daef08489910a
Autor:
Lorena Barata, María de Hoz-Rivera, Angela Romero, María Martínez, Laura Silva, María Villa, Leticia Campa, Laura Jiménez-Sánchez, José Martínez-Orgado
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Hypoxic–ischemic (HI) insults have important deleterious consequences in newborns, including short-term morbidity with neuromotor and cognitive disturbances. Cannabidiol (CBD) has demonstrated robust neuroprotective effects and shows an
Externí odkaz:
https://doaj.org/article/2c5086d654864d69b4f82a0831aa753b
Autor:
María Ceprián, Carlos Vargas, Laura García-Toscano, Federica Penna, Laura Jiménez-Sánchez, Svein Achicallende, Izaskun Elezgarai, Pedro Grandes, William Hind, M. Ruth Pazos, José Martínez-Orgado
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Neonatal hypoxia-ischemia (HI) is a risk factor for myelination disturbances, a key factor for cerebral palsy. Cannabidiol (CBD) protects neurons and glial cells after HI insult in newborn animals. We hereby aimed to study CBD’s effects on long-las
Externí odkaz:
https://doaj.org/article/b1eecfa0b96d4d7dbee8c646bf4014db
Autor:
Carlos Vargas, José Martínez-Orgado, Laura Jiménez-Sánchez, William H Hind, Lorena Barata, María Ceprián
Publikováno v:
Neuropharmacology. 116:151-159
Background and purpose: Currently there is no effective treatment for neonatal arterial ischemic stroke (AIS). Cannabidiol (CBD) is neuroprotective in models of newborn hypoxic-ischemic brain damage and adult stroke. The purpose of this work was to s
Autor:
Laura Jiménez-Sánchez, Maria CEPRIAN-COSTOSO, Julita Kulbacka, Danuta Nowakowska, María Ruth Pazos, Jose Martinez-Orgado
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 16:102-108
Background: A relevant therapeutic time window (TTW) is an important criterion for considering the clinical relevance of a substance preventing newborn hypoxic-ischemic (HI) brain damage. Objective: To test the TTW of the neuroprotective effects of c
Autor:
M. Ruth Pazos, José Martínez-Orgado, Laura Jiménez-Sánchez, Hector Lafuente, Francisco-José Alvarez, María Ceprián, Leticia Campa, Alberto Cabañas, Carlos Vargas, Lorena Barata
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Background: Newborn pigs offer theoretical advantages for studying newborn hypoxic–ischemic (HI) brain damage because of a development and structure similar to the human brain. However, the correlation between functional features and actual HI brai
Autor:
Fuencisla Pilar-Cuéllar, Laura Jiménez-Sánchez, Angel Pazos, Leticia Campa, Albert Adell, Rebeca Vidal, Álvaro Díaz, Raquel Linge
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Cannabidiol (CBD), the main non-psychotomimetic component of marihuana, exhibits anxiolytic-like properties in many behavioural tests, although its potential for treating major depression has been poorly explored. Moreover, the mechanism of action of