Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Laura J. Smithson"'
Publikováno v:
Current Opinion in Neurobiology. 53:110-119
Signaling through the dual leucine zipper-bearing kinase (DLK) is required for injured neurons to initiate new axonal growth; however, activation of this kinase also leads to neuronal degeneration and death in multiple models of injury and neurodegen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af249d84f8c3b79ed070ac9f849f0733
https://doi.org/10.1016/j.conb.2018.07.002
https://doi.org/10.1016/j.conb.2018.07.002
Publikováno v:
Oncotarget
// Yuan Pan 1 , Laura J. Smithson 1 , Yu Ma 1 , Dolores Hambardzumyan 2 , David H. Gutmann 1 1 Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA 2 Department of Oncology, Aflac Cancer and Blood Disorders Center, Em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcea2334271c6f3c617ed439eac6d43a
http://europepmc.org/articles/PMC5464843
http://europepmc.org/articles/PMC5464843
Autor:
Laura J. Smithson, David H. Gutmann
Publikováno v:
Genes & Development. 30:1383-1388
As a critical regulator of cell growth, the mechanistic target of rapamycin (mTOR) protein operates as part of two molecularly and functionally distinct complexes. Herein, we demonstrate that mTOR complex molecular composition varies in different som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124d4429560984cec82877eb5df285cd
https://doi.org/10.1101/gad.279661.116
https://doi.org/10.1101/gad.279661.116
Publikováno v:
Neurobiology of Aging. 35:2812-2821
Aberrant sympathetic sprouting is seen in the uninjured trigeminal ganglia of transgenic mice that ectopically express nerve growth factor under the control of the glial fibrillary acidic protein promoter. These sympathetic axons form perineuronal pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddbe9b2a64f83f3ebde3f553226ad8a6
https://doi.org/10.1016/j.neurobiolaging.2014.06.014
https://doi.org/10.1016/j.neurobiolaging.2014.06.014
Autor:
Ran Chen, Corina Anastasaki, Sidney B. Williams, David H. Gutmann, Laura J. Smithson, Joseph A. Toonen
Publikováno v:
Seminars in celldevelopmental biology. 58
The formation and maintenance of an organism are highly dependent on the orderly control of cell growth, differentiation, death, and migration. These processes are tightly regulated by signaling cascades in which a limited number of molecules dictate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ede9805352ce8c8d6c78e913cce2f94
https://pubmed.ncbi.nlm.nih.gov/27269372
https://pubmed.ncbi.nlm.nih.gov/27269372
Publikováno v:
Intensive Care Medicine Experimental
Background Serum biomarkers may play a role in prognostication after cardiac arrest. This study was designed to assess the feasibility of using two-dimensional gel electrophoresis (2D-GE) coupled with mass spectrometry (MS) as a proteomic strategy to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172b13a68c3ca77dfaca277c56b618d9
http://europepmc.org/articles/PMC4864914
http://europepmc.org/articles/PMC4864914
Nerve growth factor promoter activity revealed in mice expressing enhanced green fluorescent protein
Autor:
Janet Elliott, Bernadeta Michalski, Michael D. Kawaja, Gina Trinh, Margaret Fahnestock, Laura J. Smithson, Anne-Marie Crotty
Publikováno v:
The Journal of Comparative Neurology. 519:2522-2545
Nerve growth factor (NGF) and its precursor proNGF are perhaps the best described growth factors of the mammalian nervous system. There remains, however, a paucity of information regarding the precise cellular sites of proNGF/NGF synthesis. Here we r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b323ebfbad80e313b0e09251eb73c2
https://doi.org/10.1002/cne.22629
https://doi.org/10.1002/cne.22629
Autor:
Kairong Li, Corina Anastasaki, David H. Gutmann, Robert A. Kesterson, Scott M. Gianino, Joseph A. Toonen, Laura J. Smithson
Publikováno v:
Human molecular genetics. 25(9)
Neurofibromatosis type 1 (NF1) is a common neurogenetic condition characterized by significant clinical heterogeneity. A major barrier to developing precision medicine approaches for NF1 is an incomplete understanding of the factors that underlie its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8386809d1ef21bf6648ba15950387b31
https://pubmed.ncbi.nlm.nih.gov/26908603
https://pubmed.ncbi.nlm.nih.gov/26908603
Autor:
Michael D. Kawaja, Laura J. Smithson
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8472f880eaf00479796b79702e2e23b2
https://doi.org/10.1096/fasebj.27.1_supplement.316.2
https://doi.org/10.1096/fasebj.27.1_supplement.316.2
Publikováno v:
Brain research. 1521
Olfactory ensheathing cells (OECs) are the chief glial population of the mammalian olfactory nervous system, residing in the olfactory mucosa and at the surface of the olfactory bulb. We investigated the neurochemical features of OECs in a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a46133cec4a9b8f6139bcb8ce10db2
https://pubmed.ncbi.nlm.nih.gov/23665391
https://pubmed.ncbi.nlm.nih.gov/23665391