Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Laura J. Handy"'
Autor:
Laura J. Handy, Lauren Buxton, Misty D. Smith, E. Jill Dahle, Peter J. West, Karen S. Wilcox, Chelsea D. Pernici, Cameron S. Metcalf, Kristina Johnson, Jeffrey Amoako Mensah
Publikováno v:
Epilepsia
SummaryObjectiveDravet syndrome (DS) is a rare, but catastrophic genetic epilepsy, with 80% of patients with carrying a mutation in the SCN1A gene. Currently, no anti-seizure drug (ASD) exists that adequately controls seizures. Patients with DS often
Autor:
Jose H. Woodhead, Megan Hunt, Laura J. Handy, Karen White, Karen S. Wilcox, Timothy H. Pruess, Misty D. Smith, Fabiola Vanegas, Joel Grussendorf, Reisa K. Krumin, Karolina K. Bulaj, Erin Grussendorf
Publikováno v:
Neurochemical Research. 42:1995-2010
The series of experiments herein evaluated prototype drugs representing different mechanisms of antiseizure, antinociceptive or antidepressant action in a battery of preclinical pain models in adult male CF#1 mice (formalin, writhing, and tail flick)
Autor:
Gerald W. Saunders, Matthew J. Mau, Laura J. Handy, Rizvana Khaleel, Timothy H. Pruess, Jennifer Huff, Karen S. Wilcox, Melissa Barker-Haliski, Zhenmei Lu, Peter J. West, Misty D. Smith, Tristan K. Underwood, Fabiola Vanegas, Peggy Billingsley, Kristina Johnson, Carlos B. Rueda
Publikováno v:
Neurochem Res
The successful identification of promising investigational therapies for the treatment of epilepsy can be credited to the use of numerous animal models of seizure and epilepsy for over 80 years. In this time, the maximal electroshock test in mice and