Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Laura J. Draski"'
Autor:
Sarah E. Hoffmann, Tina Fay, Pequita Bludeau, Laura J. Draski, Richard A. Deitrich, Joel Edwards, Xin-Sheng Deng, Kristy Lundquist, William Asperi, Richard A. Radcliffe, V. Gene Erwin
Publikováno v:
Alcoholism: Clinical & Experimental Research. 28:1796-1804
BACKGROUND Genetic variance in initial sensitivity to ethanol has been implicated as a risk factor for the development of alcoholism. Identification of the genes that confer differential initial sensitivity is an important goal for the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5f6597e8685abdf30dd5e0cc158d85
https://doi.org/10.1097/01.alc.0000148106.71801.d7
https://doi.org/10.1097/01.alc.0000148106.71801.d7
Publikováno v:
Alcoholism: Clinical and Experimental Research. 21:661-665
Ethanol sensitive long-sleep (LS) and ethanol resistant short-sleep (SS) mice are lines that have been genetically selected for differential central nervous system sensitivities to the hypnotic effect of ethanol. Because they were genetically selecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68caf8eeca14ce28e28d1abd6c1c298b
https://doi.org/10.1111/j.1530-0277.1997.tb03819.x
https://doi.org/10.1111/j.1530-0277.1997.tb03819.x
Autor:
Richard A. Deitrich, Svetlana V. Chochina, W. Gibson Wood, Nicolai A. Avdulov, Laura J. Draski
Publikováno v:
Alcoholism: Clinical and Experimental Research. 19:886-891
In this study, we examined if differences in initial membrane sensitivity to ethanol were associated with development of membrane tolerance to ethanol. High Alcohol Sensitivity (HAS) and Low Alcohol Sensitivity (LAS) rats were administered a 15% etha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bc7b6338052d54d5256db57f56b736
https://doi.org/10.1111/j.1530-0277.1995.tb00963.x
https://doi.org/10.1111/j.1530-0277.1995.tb00963.x
Publikováno v:
Brain Research. 645:69-77
Mice that were homozygous recessive for the single-gene mutation, hotfoot, showed profound and progressive motor disturbances in an open field after approximately the 4th postnatal week. Studies were undertaken to examine the role of the monoaminergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a615c862c7c277c66b0557d1bf4d06d6
https://doi.org/10.1016/0006-8993(94)91639-x
https://doi.org/10.1016/0006-8993(94)91639-x
Autor:
Mark R. Kelley, Laura J. Draski, Nicholas V. Emanuele, John J. Tentler, M. M. Halloran, Mary Ann Emanuele
Publikováno v:
Endocrine Research. 19:317-329
The recent availability of genetically altered rat lines differing in sensitivity to ethanol (EtOH) has allowed deeper investigation into the mechanisms of EtOH-induced cellular toxicity in several systems. Since the male central reproductive axis ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997ef0432497624e8f6b8a096d560dd7
https://doi.org/10.1080/07435809309026685
https://doi.org/10.1080/07435809309026685
Publikováno v:
Alcohol. 9:323-326
A comparison of the two major ceramide molecular species (d18:1-C18:0 and d20:1-C18:0) of synaptosomal gangliosides GM1, GD1a+GT1a, GD1b, GT1b, revealed a difference between the ceramide composition of ethanol-sensitive LS and ethanol-insensitive SS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549e2d53e0f2f4c6b930c6a14b7be0e9
https://doi.org/10.1016/0741-8329(92)90074-k
https://doi.org/10.1016/0741-8329(92)90074-k
Autor:
Jeffery T. Collins, Laura J. Draski, Allan C. Collins, Richard A. Deitrich, Christopher M. de Fiebre, Elena Romm
Publikováno v:
Alcoholism: Clinical and Experimental Research. 15:270-276
Alcoholics are almost invariably heavy users of tobacco. Both alcoholism and smoking appear to be influenced by genetic factors but it is not known whether the same or different genes regulate the abuse of ethanol and nicotine. Recent studies have de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006cac3098ef4aae1db124c591ed956d
https://doi.org/10.1111/j.1530-0277.1991.tb01868.x
https://doi.org/10.1111/j.1530-0277.1991.tb01868.x
Publikováno v:
Pharmacology, biochemistry, and behavior. 70(2-3)
Initial sensitivity and acute tolerance to ethanol have been implicated as risk factors in the development of alcoholism in humans. These behaviors were investigated in rats selectively bred for differences in hypnotic sensitivity following their fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b67300a49f1b3596ee8c1447bc7bc1
https://pubmed.ncbi.nlm.nih.gov/11701212
https://pubmed.ncbi.nlm.nih.gov/11701212
Publikováno v:
Pharmacology, biochemistry, and behavior. 57(4)
Rats selectively bred for high alcohol sensitivity (HAS) or low alcohol sensitivity (LAS) were tested for initial sensitivity to hypnotic doses of ethanol and a locomotor-altering dose of phenobarbital. Following 6 weeks of either a pair-fed control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345cbc673630fa5ae6bc62bd4c0b240e
https://pubmed.ncbi.nlm.nih.gov/9258990
https://pubmed.ncbi.nlm.nih.gov/9258990
Publikováno v:
Alcoholism, clinical and experimental research. 20(4)
This study was performed to examine ethanol self-administration in rats bred for different sensitivities to the sedative effects of alcohol [the Colorado High Alcohol Sensitive (HAS) and Low Alcohol Sensitive (LAS) rats]. Four rats from each replicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3eec19a23931a5bcfeda9b9080a9cb
https://pubmed.ncbi.nlm.nih.gov/8800384
https://pubmed.ncbi.nlm.nih.gov/8800384