Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laura J. Betz"'
Autor:
Suramya Waidyanatha, Kristine L. Witt, Madelyn C. Huang, Veronica G. Robinson, Helen Cunny, Dori R. Germolec, Johnathan Furr, Keith R. Shockley, Laura J. Betz
Publikováno v:
Food Chem Toxicol
There is widespread human exposure to deoxynivalenol (DON), a fungal mycotoxin found globally in many grain-based foods and animal feed. Acute exposures to high levels of DON are associated with gastrointestinal effects and emesis in humans and some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d876bd643b9c4776ccb5437c8b4f1ff2
https://doi.org/10.1016/j.fct.2020.111963
https://doi.org/10.1016/j.fct.2020.111963
Autor:
Laura J. Betz, Felicia Riordan, Vicki Sutherland, Bradley J. Collins, Kristin Aillon, Suramya Waidyanatha, Helen Cunny, Katie J. Turner, Sandra J. McBride
Publikováno v:
Toxicol Appl Pharmacol
Due to structural similarity to bisphenol A and lack of safety data, the National Toxicology Program (NTP) is evaluating the potential toxicity of bisphenol AF (BPAF) in rodent models. The current investigation reports the internal exposure data for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a13b7c15b0637297fecfade816afa2
https://doi.org/10.1016/j.taap.2020.115369
https://doi.org/10.1016/j.taap.2020.115369
Publikováno v:
Toxicologic pathology. 44(6)
In order to harmonize diagnostic terminology, confirm diagnostic criteria, and describe aspects of tumor biology characteristic of different tumor types, a total of 165 cases of mesenchyme-related tumors and nephroblastomas of the rat kidney were ree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779fc29c74699bb0552056caa994f326
https://pubmed.ncbi.nlm.nih.gov/27169591
https://pubmed.ncbi.nlm.nih.gov/27169591
Publikováno v:
Toxicologic Pathology. 39:381-389
The occurrence and severity of spontaneous chronic progressive nephropathy (CPN) in control male F344 rats as well as the frequency of treatment-related CPN exacerbation were histopathologically reevaluated. A series of 43 National Toxicology Program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a5c5c1fe3bb5aa836aabd868dcf6a6
https://doi.org/10.1177/0192623310388432
https://doi.org/10.1177/0192623310388432
Publikováno v:
Toxicologic Pathology. 36:388-396
The Toxicology Data Management System (TDMS) of the National Toxicology Program, National Institutes of Environmental Health Sciences, National Institutes of Health, was surveyed for occurrence and distribution of a distinctive renal tubule tumor typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17becfa50782c3e0c3524f88fbbf833a
https://doi.org/10.1177/0192623308315829
https://doi.org/10.1177/0192623308315829
Publikováno v:
Food and Chemical Toxicology. 45:600-608
Renal histopathology in the most recent 2-year carcinogenicity bioassay of quercetin, in Fischer 344 rats, was re-evaluated in an attempt to determine a mode of action underlying a small increase in renal tubule tumors reported in the males (NTP, 199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc03ca4ba2778bafdb15dcec3a67639
https://doi.org/10.1016/j.fct.2006.10.018
https://doi.org/10.1016/j.fct.2006.10.018
Publikováno v:
Journal of the American Association for Laboratory Animal Science : JAALAS. 51(5)
Circumstances can occur that prevent timely analysis of blood samples. The purpose of this study was to characterize artifactual changes in rat hematologic parameters after storage of samples at 3 and 21 °C and to document the effects of storage on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6e8b97e96d955c3209ef9e8897e0c3a
https://pubmed.ncbi.nlm.nih.gov/23312091
https://pubmed.ncbi.nlm.nih.gov/23312091
Publikováno v:
Toxicologic pathology. 40(3)
From the archives of the National Toxicology Program, National Institutes of Health, kidney sections from twenty-four carcinogenicity studies (representing twenty-three chemicals) in male and female F344 rats were histopathologically re-evaluated to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd9c03f9f7e5e728b73578e6a247a27
https://pubmed.ncbi.nlm.nih.gov/22298794
https://pubmed.ncbi.nlm.nih.gov/22298794
Autor:
Kimberly A. McAllister, Roger W. Wiseman, L. Michelle Bennett, Barbara J. Davis, Jason Malphurs, William Gersch, Laura Wharey, Toni Ward, Christopher D. Houle, Laura J. Betz, N. Keith Collins, John C. Seely
Publikováno v:
Toxicologic pathology. 34(2)
Mutations in both p53 and BRCA2 are commonly seen together in human tumors suggesting that the loss of both genes enhances tumor development. To elucidate this interaction in an animal model, mice lacking the carboxy terminal domain of Brca2 were cro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629213d34c79a743bd6d12ca9b891df4
https://pubmed.ncbi.nlm.nih.gov/16546942
https://pubmed.ncbi.nlm.nih.gov/16546942