Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Laura J. Bayston"'
Publikováno v:
Nature. 455:72-77
Dorsal-ventral patterning in vertebrate and invertebrate embryos is mediated by a conserved system of secreted proteins that establishes a bone morphogenetic protein (BMP) gradient. Although the Drosophila embryonic Decapentaplegic (Dpp) gradient has
Autor:
Paul T. Spellman, Jon C. Aster, Yong Zou, Mimansa Sharma, Isaac M. Neuhaus, Charlotte M. Proby, Pui-Yan Kwok, Lakshmi Jakkula, Joe W. Gray, Stephen C. Blacklow, Kyunghee Park, Philip E. LeBoit, Joe S Hur, Laura J. Bayston, Zachary Sanborn, James E. Cleaver, Wilson Liao, Swapna S. Vemula, Theodora M. Mauro, Pierre P. Massion, Nicholas J. Wang, Andrew P. South, Jeffrey P. North, Allen E. Bale, Eric A. Collisson, Irene M. Leigh, Sally D. Pennypacker, Raymond J. Cho, Nam Huh, Sarah T. Arron, David Haussler, Kelly L. Arnett, Patricia B. Gordon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(43)
Squamous cell carcinomas (SCCs) are one of the most frequent forms of human malignancy, but, other than TP53 mutations, few causative somatic aberrations have been identified. We identified NOTCH1 or NOTCH2 mutations in ∼75% of cutaneous SCCs and i
Autor:
Ronald T. Hay, Ellis Jaffray, Susan G. Campbell, Mark P. Ashe, Mingfa Li, Laura J. Bayston, Shugaku Takeda, Wayne O. Miles, Hilary L. Ashe, Laurel A. Raftery, Sanjay Basu
Publikováno v:
Genesdevelopment. 22(18)
Morphogens are secreted signaling molecules that form concentration gradients and control cell fate in developing tissues. During development, it is essential that morphogen range is strictly regulated in order for correct cell type specification to