Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Laura J White"'
Autor:
Rita M Meganck, Deanna Zhu, Stephanie Dong, Lisa J Snoderly-Foster, Yago R Dalben, Devina Thiono, Laura J White, Arivianda M DeSilva, Ralph S Baric, Longping V Tse
Publikováno v:
eLife, Vol 12 (2023)
A hallmark of dengue virus (DENV) pathogenesis is the potential for antibody-dependent enhancement, which is associated with deadly DENV secondary infection, complicates the identification of correlates of protection, and negatively impacts the safet
Externí odkaz:
https://doaj.org/article/052e2b8492e2439d954641c9e43adbfa
Autor:
Laura J White, Ellen F Young, Mark J Stoops, Sandra R Henein, Elizabeth C Adams, Ralph S Baric, Aravinda M de Silva
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009258 (2021)
The four dengue virus serotypes (DENV1-4) infect several hundred million people each year living in tropical and sub-tropical regions. Clinical development of DENV vaccines is difficult because immunity to a single serotype increases risk of severe d
Externí odkaz:
https://doaj.org/article/3bc10f712c7a48a7b7795425067dcfd9
Autor:
Viswanathan Ramasamy, Upasana Arora, Rahul Shukla, Ankur Poddar, Rajgokul K Shanmugam, Laura J White, Melissa M Mattocks, Rajendra Raut, Ashiya Perween, Poornima Tyagi, Aravinda M de Silva, Siddhartha K Bhaumik, Murali Krishna Kaja, François Villinger, Rafi Ahmed, Robert E Johnston, Sathyamangalam Swaminathan, Navin Khanna
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006191 (2018)
Dengue is one of the fastest spreading vector-borne diseases, caused by four antigenically distinct dengue viruses (DENVs). Antibodies against DENVs are responsible for both protection as well as pathogenesis. A vaccine that is safe for and efficacio
Externí odkaz:
https://doaj.org/article/1493e4510e824e5a9dcf9fc2b8abf687
Autor:
Raphaël M Zellweger, Robyn Miller, William E Eddy, Laura J White, Robert E Johnston, Sujan Shresta
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003723 (2013)
With 2.5 billion people at risk, dengue is a major emerging disease threat and an escalating public health problem worldwide. Dengue virus causes disease ranging from a self-limiting febrile illness (dengue fever) to the potentially fatal dengue hemo
Externí odkaz:
https://doaj.org/article/a1b0b6c5f9b54880a29cd0b5f55e8171
Autor:
Carlos A Sariol, Melween I Martínez, Francheska Rivera, Idia Vanessa Rodríguez, Petraleigh Pantoja, Kristina Abel, Teresa Arana, Luis Giavedoni, Vida Hodara, Laura J White, Yesseinia I Angleró, Luis J Montaner, Edmundo N Kraiselburd
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19323 (2011)
Pathogenic versus protective outcomes to Dengue virus (DENV) infection are associated with innate immune function. This study aimed to determine the role of increased TLR3- and TLR7/8-mediated innate signaling after Dengue infection of rhesus macaque
Externí odkaz:
https://doaj.org/article/537fe374a68a40a9a48063535520f481
Autor:
Jennifer L Konopka, Luiz O Penalva, Joseph M Thompson, Laura J White, Clayton W Beard, Jack D Keene, Robert E Johnston
Publikováno v:
PLoS Pathogens, Vol 3, Iss 12, p e199 (2007)
A concept fundamental to viral pathogenesis is that infection induces specific changes within the host cell, within specific tissues, or within the entire animal. These changes are reflected in a cascade of altered transcription patterns evident duri
Externí odkaz:
https://doaj.org/article/c4134ec5a1674c579635d18a29172451
Autor:
Rita M. Meganck, Deanna Zhu, Stephanie Dong, Lisa J. Snoderly-Foster, Yago R. Dalben, Devina Thiono, Laura J. White, Aravinda M. DeSilva, Ralph S. Baric, Longping V. Tse
Publikováno v:
bioRxiv
A hallmark of Dengue virus (DENV) pathogenesis is the potential for antibody-dependent enhancement, which is associated with deadly DENV secondary infection, complicates the identification of correlates of protection, and negatively impacts the safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ed5d83705e9b49ba9f8de7f86938f1
https://europepmc.org/articles/PMC10081285/
https://europepmc.org/articles/PMC10081285/
Autor:
Longping V. Tse, Rita M. Meganck, Stephanie Dong, Lily E. Adams, Laura J. White, Michael L. Mallory, Ramesh Jadi, Aravinda M. de Silva, Ralph S. Baric
Publikováno v:
mBio. 13
Mature DENVs represent the dominant form in vivo and are the target for vaccine development. Here, we used multiple strategies, including protein engineering and natural and directed evolution to generate DENV1, -2, -3, and -4 variants that are highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a4532c9ae65fcd891fd222da15c327
https://doi.org/10.1128/mbio.00386-22
https://doi.org/10.1128/mbio.00386-22
Autor:
Laura M. Parodi, Petraleigh Pantoja, Alexandra Ortiz-Rosa, Amelia K. Pinto, Crisanta Serrano-Collazo, Luis D. Giavedoni, Aravinda M. de Silva, Mariah Hassert, Teresa Arana, Laura J. White, Erick X. Pérez-Guzmán, James D. Brien, Daniela Weiskopf, Carlos A. Sariol, Melween I. Martínez, Idia V. Rodríguez, Lorna Cruz, Vida L. Hodara
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Zika virus (ZIKV) and dengue virus (DENV) are co-endemic in many parts of the world, but the impact of ZIKV infection on subsequent DENV infection is not well understood. Here we show in rhesus macaques that the time elapsed after ZIKV infection affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7182c449f50fc049a687b443b4f4782e
https://doaj.org/article/df47fefed1b64aed9ca8592422e25d1d
https://doaj.org/article/df47fefed1b64aed9ca8592422e25d1d
Autor:
S. Dong, Rita M. Meganck, Laura J. White, Longping V. Tse, Ralph S. Baric, Lily E. Adams, Aravinda Desilva
Maturation of Dengue viruses (DENV) alters the structure, immunity and infectivity of the virion and highly mature particles represent the dominant form in vivo. The production of highly mature virions principally relies on the structure and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2cff41aa33c70cd88e14e762a011ada
https://doi.org/10.1101/2021.04.06.438747
https://doi.org/10.1101/2021.04.06.438747