Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Laura J Szewczyk"'
Autor:
William A. Fischer, Joseph J. Eron, Wayne Holman, Myron S. Cohen, Lei Fang, Laura J. Szewczyk, Timothy P. Sheahan, Ralph Baric, Katie R. Mollan, Cameron R. Wolfe, Elizabeth R. Duke, Masoud M. Azizad, Katyna Borroto-Esoda, David A. Wohl, Robert W. Coombs, Amy James Loftis, Paul Alabanza, Felicia Lipansky, Wendy P. Painter
Publikováno v:
medRxiv
There is an urgent need for an effective, oral, direct-acting therapeutic to block transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression to severe coronavirus disease 2019 (COVID-19). In a phase 2a doubl
Autor:
Katie R Mollan, Joseph J Eron, Taylor J Krajewski, Wendy Painter, Elizabeth R Duke, Caryn G Morse, Erin A Goecker, Lakshmanane Premkumar, Cameron R Wolfe, Laura J Szewczyk, Paul L Alabanza, Amy James Loftis, Emily J Degli-Angeli, Ariane J Brown, Joan A Dragavon, John J Won, Jessica Keys, Michael G Hudgens, Lei Fang, David A Wohl, Myron S Cohen, Ralph S Baric, Robert W Coombs, Timothy P Sheahan, William A Fischer
Publikováno v:
Clin Infect Dis
Background Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectious virus isolation in outpatients with coronavirus disease 2019 (COVID-19) has been associated with viral RNA levels and symptom duration, little is known about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f31f7dab0d81bbcca208a91619e07a
https://europepmc.org/articles/PMC9402664/
https://europepmc.org/articles/PMC9402664/
Autor:
Laura J. Szewczyk, Myron S. Cohen, Paul Alabanza, Elizabeth R. Duke, David A. Wohl, Wayne Holman, Timothy P. Sheahan, Cameron R. Wolfe, Katie R. Mollan, Felicia Lipansky, Katyna BorrotoiEsoda, William A. Fischer, Amy James Loftis, Ralph S. Baric, Lei Fang, Wendy Painter, Masoud M Azizad, Joseph J. Eron
Publikováno v:
medRxiv : the preprint server for health sciences.
BackgroundEasily distributed oral antivirals are urgently needed to treat coronavirus disease-2019 (COVID-19), prevent progression to severe illness, and block transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report th
Infectious SARS-CoV-2 Virus in Symptomatic COVID-19 Outpatients: Host, Disease, and Viral Correlates
Autor:
Robert W. Coombs, Ariane J. Brown, Myron S. Cohen, David A. Wohl, Joan Dragavon, John J. Won, William A. Fischer, Timothy P. Sheahan, Elizabeth R. Duke, Ralph S. Baric, Cameron R. Wolfe, Taylor J. Krajewski, Laura J. Szewczyk, Emily J. Degli-Angeli, Amy James Loftis, Caryn G. Morse, Paul Alabanza, Michael G. Hudgens, Lei Fang, Erin A. Goecker, Katie R. Mollan, Lakshmanane Premkumar, Wendy Painter, Jessica Keys, Joseph J. Eron
Background SARS-CoV-2 infectious virus isolation in the upper airway of COVID-19 patients is associated with higher levels of viral RNA. However, comprehensive evaluation of the relationships between host and disease factors and infectious, replicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efc3f7f53ebbef638450729f002a0e0f
https://doi.org/10.1101/2021.05.28.21258011
https://doi.org/10.1101/2021.05.28.21258011
Autor:
Wendy Painter, Nicola C. J. E. Eraut, Jim A. Bush, Laura J. Szewczyk, Hamzah Malik, Merribeth J. Morin, Wayne Holman, Firas Almazedi, George R. Painter
Publikováno v:
Antimicrobial Agents and Chemotherapy
Molnupiravir (EIDD-2801/MK-4482), the prodrug of the active antiviral ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931), has activity against a number of RNA viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)