Changes in Postural Syntax Characterize Sensory Modulation and Natural Variation of C. elegans Locomotion.

Autor: Roland F Schwarz, Robyn Branicky, Laura J Grundy, William R Schafer, André E X Brown

Publikováno v: PLoS Computational Biology, Vol 11, Iss 8, p e1004322 (2015)

Locomotion is driven by shape changes coordinated by the nervous system through time; thus, enumerating an animal's complete repertoire of shape transitions would provide a basis for a comprehensive understanding of locomotor behaviour. Here we intro

Externí odkaz: https://doaj.org/article/0294fae3f1d34cc78b8ce512065f77a8

The Bright Fluorescent Protein mNeonGreen Facilitates Protein Expression Analysis In Vivo

Autor: Dominique A. Glauser, William R Schafer, Stéphanie Käser-Pébernard, Laura J Grundy, Lola Hostettler, Chantal Wicky

Publikováno v: G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 7, Iss 2, Pp 607-615 (2017)

The Green Fluorescent Protein (GFP) has been tremendously useful in investigating cell architecture, protein localization, and protein function. Recent developments in transgenesis and genome editing methods now enable working with fewer transgene co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fc3c5a8fbddea85d0e474dc34a31de
https://doi.org/10.1534/g3.116.038133

PACRG, a protein linked to ciliary motility, mediates cellular signaling

Autor: Catrina M. Loucks, Nathan J. Bialas, William R Schafer, Oliver E. Blacque, Laura J Grundy, P. Nick Inglis, Michel R. Leroux, Chunmei Li, Martijn P. J. Dekkers, Denise S. Walker, Katarzyna Kida, Gert Jansen

Publikováno v: Molecular Biology of the Cell, 27(13), 2133-2144. American Society for Cell Biology
Molecular Biology of the Cell
Loucks, Catrina M; Bialas, Nathan J; Dekkers, Martijn; Walker, Denise S; Grundy, Laura J; Li, Chunmei; Inglis, P Nick; Kida, Katarzyna; Schafer, William R; Blacque, Oliver E; Jansen, Gert; Leroux, Michel R (2016). PACRG, a protein linked to ciliary motility, mediates cellular signaling. Molecular biology of the cell, 27(13), pp. 2133-2144. American Society for Cell Biology 10.1091/mbc.E15-07-0490

Cilia are cellular projections that can be motile to generate fluid flow or nonmotile to enable signaling. Both forms are based on shared components, and proteins involved in ciliary motility, like PACRG, may also function in ciliary signaling. Caeno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28826c7a822e0f4c3574d3d4c6409955
https://doi.org/10.1091/mbc.e15-07-0490

Neuropeptides encoded by

Autor: Yee Lian, Chew, Laura J, Grundy, André E X, Brown, Isabel, Beets, William R, Schafer

Publikováno v: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 373(1758)

Neuropeptide signalling has been implicated in a wide variety of biological processes in diverse organisms, from invertebrates to humans. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e5fc5955a7d04cbf042ea30a524f3c1
https://pubmed.ncbi.nlm.nih.gov/30201834

Automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans

Autor: Laura J Grundy, William R Schafer, Hyundoo Hwang, Hang Lu, Yongmin Cho, Daniel A. Porto

Publikováno v: Lab on a Chip

C. elegans is a useful genetic model system for investigating mechanisms involved in sensory behavior which are potentially relevant to human diseases. While utilities of advanced techniques such as microfluidics have accelerated some areas of C. ele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1beb776971df55c6d09755445fab798d
https://pubmed.ncbi.nlm.nih.gov/29063096