Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Laura J Bonnett"'
Autor:
Gashirai K Mbizvo, Glen P Martin, Matthew Sperrin, Laura J Bonnett, Pieta Schofield, Iain Buchan, Gregory Y H Lip, Anthony G Marson
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0306226 (2024)
Valproate is the most effective treatment for idiopathic generalised epilepsy. Currently, its use is restricted in women of childbearing potential owing to high teratogenicity. Recent evidence extended this risk to men's offspring, prompting recommen
Externí odkaz:
https://doaj.org/article/add00988003b43b8b1d761bcbefad8e6
Autor:
Richard Thomas, Holly Tibble, Laura J Bonnett, Luke Daines, David Price, Steff C Lewis, Hilary Pinnock, Andy Boyd, Aziz Sheikh, Steve W Turner
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Introduction: Accurately diagnosing asthma can be challenging. We aimed to derive and validate a prediction model to support primary care clinicians assess the probability of an asthma diagnosis in children and young people. Methods: The derivation d
Externí odkaz:
https://doaj.org/article/09f7e997b1eb43cf89175093c147cc30
Autor:
Richard M Jacques, Rebecca M Simpson, Suzanne M Mason, Laura J Bonnett, Adam J Noble, Anthony Guy Marson, Markus Reuber, Richard Pilbery, Jon Mark Dickson, Alison Fuller, Richard Campbell, Jasmine Wright
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction Ambulances services are asked to further reduce avoidable conveyances to emergency departments (EDs). Risk of Adverse Outcomes after a Suspected Seizure seeks to support this by: (1) clarifying the risks of conveyance and non-conveyance,
Externí odkaz:
https://doaj.org/article/6a1febd45e864405ae86bbdc5e9ce72e
Autor:
Joseph Kamtchum-Tatuene, Henry C Mwandumba, Gloria Mwangalika Kachingwe, Laura J Bonnett, Noel Kayange, Tom Solomon, Laura A Benjamin
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229033 (2020)
BackgroundIn sub-Saharan Africa, there is a dearth of epidemiologic data on the burden of cerebral atherosclerosis. This is explained by the limited availability and the high cost of standard vascular imaging techniques. Neurovascular ultrasound is p
Externí odkaz:
https://doaj.org/article/eadeb6095a3a4a8eb173a41c396976a0
Publikováno v:
BMJ Open Respiratory Research, Vol 6, Iss 1 (2019)
Introduction Antibiotics are routinely given to people with chronic obstructive pulmonary disease (COPD) presenting with lower respiratory tract infection (LRTI) symptoms in primary care. Population prescribing habits and their consequences have not
Externí odkaz:
https://doaj.org/article/e99c45ee9b554f1884d5b888f69aa0e8
Breakthrough seizures-Further analysis of the Standard versus New Antiepileptic Drugs (SANAD) study.
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190035 (2017)
ObjectivesTo develop prognostic models for risk of a breakthrough seizure, risk of seizure recurrence after a breakthrough seizure, and likelihood of achieving 12-month remission following a breakthrough seizure. A breakthrough seizure is one that oc
Externí odkaz:
https://doaj.org/article/6203a4c7566b4b61af12d5c3afdbc6b6
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Predictive models within epilepsy are frequently developed via Cox’s proportional hazards models. These models estimate risk of a specified event such as 12-month remission. They are relatively simple to produce, have familiar o
Externí odkaz:
https://doaj.org/article/4bbc98769aa649ea9682fcfe34793f6c
Publikováno v:
Diagnostic and Prognostic Research, Vol 3, Iss 1, Pp 1-5 (2019)
Abstract Background Psychotic disorders affect about 3% of the population worldwide and are associated with high personal, social and economic costs. They tend to have their first onset in adolescence. Increasing emphasis has been placed on early int
Externí odkaz:
https://doaj.org/article/dc3036ec6e49472ebfe7c2c9a71b77da
Autor:
Luke Daines, Laura J. Bonnett, Andy Boyd, Steve Turner, Steff Lewis, Aziz Sheikh, Hilary Pinnock
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
Background: Accurately diagnosing asthma can be challenging. Uncertainty about the best combination of clinical features and investigations for asthma diagnosis is reflected in conflicting recommendations from international guidelines. One solution c
Externí odkaz:
https://doaj.org/article/7cf6ab5bea7348fcbddf29c9067ba771
Publikováno v:
European Clinical Respiratory Journal, Vol 5, Iss 1 (2018)
Antibiotic prescriptions for lower respiratory tract infections occur commonly in primary care but there is uncertainty about the most effective initial treatment strategy. Both increasing antimicrobial resistance and awareness of preventable harm fr
Externí odkaz:
https://doaj.org/article/71347dc5742e40ce90576a9619d65fd0