Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura J, Terlecky"'
Autor:
Laura J. Terlecky, Kitty Tang, Sandra L. Schmid, Keith E. Mostov, Shana M. Barbas, Stephen Hardy, Yoram Altschuler
Publikováno v:
The Journal of Cell Biology
The Journal of cell biology, vol 143, iss 7
The Journal of cell biology, vol 143, iss 7
A role for dynamin in clathrin-mediated endocytosis is now well established. However, mammals express three closely related, tissue-specific dynamin isoforms, each with multiple splice variants. Thus, an important question is whether these isoforms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbfb3bfeca727d83de2f27dad1ec036e
http://europepmc.org/articles/PMC2175237
http://europepmc.org/articles/PMC2175237
Peroxisomes are intracellular organelles mediating a wide variety of biosynthetic and biodegradative reactions. Included among these are the metabolism of hydrogen peroxide and other reactive species, molecules whose levels help define the oxidative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f164a0c62a464c82adc3f42893fb94f
https://europepmc.org/articles/PMC3362841/
https://europepmc.org/articles/PMC3362841/
Autor:
Kelly L. Mueller, Courtney R. Giordano, Laura J. Terlecky, Kendra A. Krentz, Stanley R. Terlecky, Julie L. Boerner, Aliccia Bollig-Fischer
Publikováno v:
Experimental cell research. 318(16)
Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) of potential use in patients with breast cancer. Unfortunately, in clinical studies, gefitinib is often ineffective indicating that resistance to EGFR inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017daa303292bfbe5e262c66be4b55d7
https://pubmed.ncbi.nlm.nih.gov/22687878
https://pubmed.ncbi.nlm.nih.gov/22687878
Autor:
Savoy L. Boyd, Chen N. Young, Jay I. Koepke, Laura J. Terlecky, Michael S. Borkin, Stanley R. Terlecky
The multifunctional cytokine tumor necrosis factor-alpha (TNF-alpha) is known to play an important role in inflammatory and immunological responses in human skin. Although it has been documented that reactive oxygen species (ROS) are involved in TNF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af23e671873ba1671a9d6bbd808f1e0
https://europepmc.org/articles/PMC4102307/
https://europepmc.org/articles/PMC4102307/
Publikováno v:
Toxicology and applied pharmacology. 232(1)
Peroxisomes generate hydrogen peroxide, a reactive oxygen species, as part of their normal metabolism. A number of pathological situations exist in which the organelle's capacity to degrade the potentially toxic oxidant is compromised. It is the pero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c7801f541225363be9f21b0922b060
https://pubmed.ncbi.nlm.nih.gov/18634817
https://pubmed.ncbi.nlm.nih.gov/18634817
Autor:
Jay I. Koepke, Paul A. Walton, Krissy K. Boucher, Christopher S. Wood, Laura J. Terlecky, Stanley R. Terlecky, Kerry Ann Nakrieko
Publikováno v:
Traffic (Copenhagen, Denmark). 8(11)
Peroxisomes play an important role in human cellular metabolism by housing enzymes involved in a number of essential biochemical pathways. Many of these enzymes are oxidases that transfer hydrogen atoms to molecular oxygen forming hydrogen peroxide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29fa5efe5c29ec48cfd0c361995ea2f
https://pubmed.ncbi.nlm.nih.gov/17822396
https://pubmed.ncbi.nlm.nih.gov/17822396
Autor:
Christopher S, Wood, Jay I, Koepke, Hua, Teng, Krissy K, Boucher, Sharon, Katz, Patrick, Chang, Laura J, Terlecky, Irene, Papanayotou, Paul A, Walton, Stanley R, Terlecky
Publikováno v:
Traffic (Copenhagen, Denmark). 7(1)
Human epidemiological studies point to an association of hypocatalasemia and an increased risk of age-related disease. Unfortunately, the cellular and molecular manifestations of hypocatalasemia are only poorly understood. In this analysis, we have e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afd8c3f6ce554a105a20b1c73cfa025b
https://pubmed.ncbi.nlm.nih.gov/16445690
https://pubmed.ncbi.nlm.nih.gov/16445690
Publikováno v:
Nature. 382:177-179
PINOCYTOSIS and membrane ruffling are among the earliest and most dramatic cellular responses to stimulation by growth factors or other mitogens1. The small Ras-related G proteins Rho and Rac have a regulatory role in membrane ruffling1–3 and activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b27556c5d584fcde1e530f3dfeba6b42
https://doi.org/10.1038/382177a0
https://doi.org/10.1038/382177a0
Autor:
Ferdous Barlaskar, Jay I. Koepke, Laura J. Terlecky, Stanley R. Terlecky, Julie E. Legakis, Holly Edwards, Christopher Jedeszko, Paul A. Walton
Publikováno v:
Molecular biology of the cell. 13(12)
The molecular mechanisms of peroxisome biogenesis have begun to emerge; in contrast, relatively little is known about how the organelle functions as cells age. In this report, we characterize age-related changes in peroxisomes of human cells. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc23bad5b1fbdfbefb4202004fa7a72
https://pubmed.ncbi.nlm.nih.gov/12475949
https://pubmed.ncbi.nlm.nih.gov/12475949
Autor:
Terlecky SR; Stanley R Terlecky, Laura J Terlecky, Courtney R Giordano, Department of Pharmacology, Wayne State University School of Medicine, 540 E. Canfield Ave., Detroit, MI 48201, United States., Terlecky LJ, Giordano CR
Publikováno v:
World journal of biological chemistry [World J Biol Chem] 2012 May 26; Vol. 3 (5), pp. 93-7.