Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Laura J, Grundy"'
1
Akademický článek
EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling
Autor: Catrina M Loucks, Kwangjin Park, Denise S Walker, Andrea H McEwan, Tiffany A Timbers, Evan L Ardiel, Laura J Grundy, Chunmei Li, Jacque-Lynne Johnson, Julie Kennedy, Oliver E Blacque, William Schafer, Catharine H Rankin, Michel R Leroux
Publikováno v: eLife, Vol 8 (2019)
Neurons throughout the mammalian brain possess non-motile cilia, organelles with varied functions in sensory physiology and cellular signaling. Yet, the roles of cilia in these neurons are poorly understood. To shed light into their functions, we stu
Externí odkaz: https://doaj.org/article/187f16f490b2476e89b17a0470140d3f
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2
The diverse functions of the DEG/ENaC family: linking genetic and physiological insights
Autor: Eva Kaulich, Laura J. Grundy, William R. Schafer, Denise S. Walker
Publikováno v: The Journal of physiologyReferences.
The DEG/ENaC family of ion channels was defined based on the sequence similarity between degenerins (DEG) from the nematode Caenorhabditis elegans and subunits of the mammalian epithelial sodium channel (ENaC), and also includes a diverse array of no
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977f4c62c2b33ab3d7e50fa0df2e7378
https://pubmed.ncbi.nlm.nih.gov/36314992
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3
Akademický článek
Changes in Postural Syntax Characterize Sensory Modulation and Natural Variation of C. elegans Locomotion.
Autor: Roland F Schwarz, Robyn Branicky, Laura J Grundy, William R Schafer, André E X Brown
Publikováno v: PLoS Computational Biology, Vol 11, Iss 8, p e1004322 (2015)
Locomotion is driven by shape changes coordinated by the nervous system through time; thus, enumerating an animal's complete repertoire of shape transitions would provide a basis for a comprehensive understanding of locomotor behaviour. Here we intro
Externí odkaz: https://doaj.org/article/0294fae3f1d34cc78b8ce512065f77a8
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4
The Bright Fluorescent Protein mNeonGreen Facilitates Protein Expression Analysis In Vivo
Autor: Dominique A. Glauser, William R Schafer, Stéphanie Käser-Pébernard, Laura J Grundy, Lola Hostettler, Chantal Wicky
Publikováno v: G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 7, Iss 2, Pp 607-615 (2017)
The Green Fluorescent Protein (GFP) has been tremendously useful in investigating cell architecture, protein localization, and protein function. Recent developments in transgenesis and genome editing methods now enable working with fewer transgene co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fc3c5a8fbddea85d0e474dc34a31de
https://doi.org/10.1534/g3.116.038133
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5
EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling
Autor: Denise S. Walker, Chunmei Li, Catharine H. Rankin, Julie Kennedy, Laura J Grundy, Kwangjin Park, Catrina M. Loucks, Jacque-Lynne Johnson, Evan L. Ardiel, Andrea H. McEwan, Oliver E. Blacque, William R Schafer, Michel R. Leroux, Tiffany A. Timbers
Publikováno v: eLife, Vol 8 (2019)
eLife
Neurons throughout the mammalian brain possess non-motile cilia, organelles with varied functions in sensory physiology and cellular signaling. Yet, the roles of cilia in these neurons are poorly understood. To shed light into their functions, we stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49af61722ad40eb95f5c8e3ad62606cd
https://elifesciences.org/articles/37271
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6
PACRG, a protein linked to ciliary motility, mediates cellular signaling
Autor: Catrina M. Loucks, Nathan J. Bialas, William R Schafer, Oliver E. Blacque, Laura J Grundy, P. Nick Inglis, Michel R. Leroux, Chunmei Li, Martijn P. J. Dekkers, Denise S. Walker, Katarzyna Kida, Gert Jansen
Publikováno v: Molecular Biology of the Cell, 27(13), 2133-2144. American Society for Cell Biology
Molecular Biology of the Cell
Loucks, Catrina M; Bialas, Nathan J; Dekkers, Martijn; Walker, Denise S; Grundy, Laura J; Li, Chunmei; Inglis, P Nick; Kida, Katarzyna; Schafer, William R; Blacque, Oliver E; Jansen, Gert; Leroux, Michel R (2016). PACRG, a protein linked to ciliary motility, mediates cellular signaling. Molecular biology of the cell, 27(13), pp. 2133-2144. American Society for Cell Biology 10.1091/mbc.E15-07-0490
Cilia are cellular projections that can be motile to generate fluid flow or nonmotile to enable signaling. Both forms are based on shared components, and proteins involved in ciliary motility, like PACRG, may also function in ciliary signaling. Caeno
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28826c7a822e0f4c3574d3d4c6409955
https://doi.org/10.1091/mbc.e15-07-0490
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8
Neuropeptides encoded by
Autor: Yee Lian, Chew, Laura J, Grundy, André E X, Brown, Isabel, Beets, William R, Schafer
Publikováno v: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 373(1758)
Neuropeptide signalling has been implicated in a wide variety of biological processes in diverse organisms, from invertebrates to humans. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e5fc5955a7d04cbf042ea30a524f3c1
https://pubmed.ncbi.nlm.nih.gov/30201834
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9
An open source platform for analyzing and sharing worm behavior data
Autor: Chee Wai Lee, Michael Currie, André Ex Brown, Eviatar Yemini, Avelino Javer, Ellen A. A. Nollen, Rex Kerr, Jim Hokanson, Quee-Lim Ch'ng, Chris Li, Laura J Grundy, Celine N. Martineau, William R Schafer, Kezhi Li
Publikováno v: Nature Methods, 15(9), 645-646. Nature Publishing Group
Animal behavior is increasingly being recorded in systematic imaging studies that generate large data sets. To maximize the usefulness of these data there is a need for improved resources for analyzing and sharing behavior data that will encourage re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93e27f24305e6ba830a76f52a27e4c6
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10
Automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans
Autor: Laura J Grundy, William R Schafer, Hyundoo Hwang, Hang Lu, Yongmin Cho, Daniel A. Porto
Publikováno v: Lab on a Chip
C. elegans is a useful genetic model system for investigating mechanisms involved in sensory behavior which are potentially relevant to human diseases. While utilities of advanced techniques such as microfluidics have accelerated some areas of C. ele
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1beb776971df55c6d09755445fab798d
https://pubmed.ncbi.nlm.nih.gov/29063096
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