Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Laura Indolfi"'
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8930 (2010)
Biological processes from embryogenesis to tumorigenesis rely on the coordinated coalescence of cells and synchronized cell-to-cell communication. Intercellular signaling enables cell masses to communicate through endocrine pathways at a distance or
Externí odkaz:
https://doaj.org/article/cef0d047f56b4270848945c4524c42ed
Autor:
Charles Pilgrim, Marty Smith, Jun Ban, Sam Ellis, John Raymond Zalcberg, Ben Markman, Margaret Lashof-Sullivan, Laura Indolfi
Publikováno v:
Journal of Clinical Oncology. 41:TPS775-TPS775
TPS775 Background: While there have been tremendous advances in cancer treatment, critical challenges remain including limited ability of drugs to successfully reach the tumor, short half-life, and low retention rate on site. Local control of non-met
Autor:
Abraham R. Tzafriri, Bryan C. Fuchs, Vikram Deshpande, Laura Indolfi, Cristina R. Ferrone, Robert Langer, Elazer R. Edelman, Vishal Thapar, Aaron B. Baker, Francesca Bersani, Daniel A. Haber, Kristina Xega, Jeffrey W. Clark, David T. Ting, Matteo Ligorio, Nicola Aceto
Publikováno v:
Biomaterials
PMC
PMC
Pancreatic ductal adenocarcinoma (PDAC) is one of the most devastating and painful cancers. It is often highly resistant to therapy owing to inherent chemoresistance and the desmoplastic response that creates a barrier of fibrous tissue preventing tr
Publikováno v:
Journal of Clinical Oncology. 38:e16747-e16747
e16747 Background: As systemic therapy improves, control of localized pancreatic adenocarcinoma (PDAC) remains a major challenge. Up to 40% of patients present with locally advanced and borderline resectable tumors, for whom enhanced local downsizing
Autor:
Laura Indolfi, Amanda L. McSweeney, Margaret Lashof-Sullivan, David T. Ting, Michael P. Kim, Ching-Wei D. Tzeng
Publikováno v:
Cancer Research. 79:B26-B26
As systemic therapy improves, local control of nonmetastatic pancreatic adenocarcinoma (PDAC) remains a major challenge. Up to 40% of patients present with locally advanced and borderline resectable anatomy, for whom enhanced local downsizing of dise
Publikováno v:
PMC
The implantation of matrix-embedded endothelial cells (MEECs) has been reported to have great therapeutic potential in controlling the vascular response to injury and maintaining patency in arteriovenous anastomoses. While there is an appreciation of
Autor:
Christopher Spruell, Mordechai Golomb, Laura Indolfi, Elazer R. Edelman, Aaron B. Baker, Israel Vlodavsky, Vijaya B. Kolachalama, Eyal Zcharia, William J. Gibson
Publikováno v:
Journal of the American College of Cardiology. 59:1551-1560
Objectives The purpose of this study was to examine the role of heparanase in controlling thrombosis following vascular injury or endovascular stenting. Background The use of endovascular stents are a common clinical intervention for the treatment of
Autor:
Paolo A. Netti, Fabiana Quaglia, Francesca Ungaro, Laura Indolfi, Marco Biondi, Maria Immacolata La Rotonda
Publikováno v:
Journal of Materials Science: Materials in Medicine. 20:2117-2128
In tissue engineering, the recapitulation of natural sequences of signaling molecules, such as growth factors, as occurring in the native extracellular matrix (ECM), is fundamental to support the stepwise process of tissue regeneration. Among the man
Publikováno v:
Journal of Materials Science: Materials in Medicine. 20:1541-1551
In this study, a spray-coating method has been set up with the aim to control the coating of poly(2-hydroxy-ethyl-methacrylate) (pHEMA), an hydrophilic polymeric hydrogel, onto the complex surface of a 316L steel stent for percutaneous coronary inter
Autor:
Aaron Baker, William Gibson, Vijaya Kolachalama, Mordechai Golomb, Laura Indolfi, Christopher Spruell, Eyal Zcharia, Israel Vlodavsky, Elazer Edelman
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32
Background: Heparanase cleaves heparan sulfate proteoglycans (HSPGs), key components of the extracellular matrix and critical endothelial mediators of hemostasis. Our previous work has shown that heparanase levels are elevated in atherosclerosis and