Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Laura I. Gil Pineda"'
Publikováno v:
Biology, Vol 12, Iss 6, p 796 (2023)
The canonical ASC domains, PYD and CARD, are interconnected by a lengthy, semi-flexible linker. The molecular basis and purpose of ASC’s highly dynamic feature remain elusive. In this study, all-atom molecular dynamics simulations were utilized to
Externí odkaz:
https://doaj.org/article/eb90a114407f42ff80accd35a8ed950a
Autor:
Laura I. Gil Pineda, Justin A. Lemkul
Publikováno v:
Biophysical Journal. 122:137a
Publikováno v:
Biophysical Journal. 121:526a-527a
Autor:
Tongtong Li, Yi He, Shenghan Song, Amy O Stevens, Laura I. Gil Pineda, Christabel A. Ameyaw Baah
Publikováno v:
Journal of Theoretical and Computational Chemistry. 19:2040007
p53 is a transcription factor with intrinsically disordered regions that plays an essential role in many cellular processes. As a tumor suppressor, the dysfunction of p53 causes various cancers. p53 can be activated by binding with cofactors in the c