Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Laura Hobley"'
Autor:
Joana Sá-Pessoa, Kornelia Przybyszewska, Filipe Nuno Vasconcelos, Amy Dumigan, Christian G. Frank, Laura Hobley, Jose A. Bengoechea
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Klebsiella pneumoniae is an important cause of multidrug-resistant infections worldwide. Understanding the virulence mechanisms of K. pneumoniae is a priority and timely to design new therapeutics. Here, we demonstrate that K. pneumoniae lim
Externí odkaz:
https://doaj.org/article/cfc9f1099b3449c086b2907f5e856696
Autor:
Daniel Storey, Alan McNally, Mia Åstrand, Joana Sa-Pessoa Graca Santos, Isabel Rodriguez-Escudero, Bronagh Elmore, Leyre Palacios, Helina Marshall, Laura Hobley, Maria Molina, Victor J Cid, Tiina A Salminen, Jose A Bengoechea
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1007969 (2020)
Klebsiella pneumoniae is recognized as an urgent threat to human health due to the increasing isolation of multidrug resistant strains. Hypervirulent strains are a major concern due to their ability to cause life-threating infections in healthy hosts
Externí odkaz:
https://doaj.org/article/937d49c1157d427bab2733881a4b420b
Autor:
Ryan J. Morris, Marieke Schor, Rachel M. C. Gillespie, Ana Sofia Ferreira, Lucia Baldauf, Chris Earl, Adam Ostrowski, Laura Hobley, Keith M. Bromley, Tetyana Sukhodub, Sofia Arnaouteli, Nicola R. Stanley-Wall, Cait E. MacPhee
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract BslA is a protein secreted by Bacillus subtilis which forms a hydrophobic film that coats the biofilm surface and renders it water-repellent. We have characterised three orthologues of BslA from Bacillus amyloliquefaciens, Bacillus lichenifo
Externí odkaz:
https://doaj.org/article/a586664c221344d0a32082a119a55168
Autor:
Timothy J Kidd, Grant Mills, Joana Sá‐Pessoa, Amy Dumigan, Christian G Frank, José L Insua, Rebecca Ingram, Laura Hobley, José A Bengoechea
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 4, Pp 430-447 (2017)
Abstract Klebsiella pneumoniae is an important cause of multidrug‐resistant infections worldwide. Recent studies highlight the emergence of multidrug‐resistant K. pneumoniae strains which show resistance to colistin, a last‐line antibiotic, ari
Externí odkaz:
https://doaj.org/article/d6fade12f1414cb382e0767ad34a44ac
Autor:
Laura Hobley, Rowena K Y Fung, Carey Lambert, Maximilian A T S Harris, Jayesh M Dabhi, Simon S King, Sarah M Basford, Kaoru Uchida, Robert Till, Rashidah Ahmad, Shin-Ichi Aizawa, Mark Gomelsky, R Elizabeth Sockett
Publikováno v:
PLoS Pathogens, Vol 8, Iss 2, p e1002493 (2012)
Bdellovibrio bacteriovorus is a Delta-proteobacterium that oscillates between free-living growth and predation on Gram-negative bacteria including important pathogens of man, animals and plants. After entering the prey periplasm, killing the prey and
Externí odkaz:
https://doaj.org/article/eefe2ffe42af4fedb0e91273f4add5da
Publikováno v:
mBio, Vol 2, Iss 5 (2011)
ABSTRACT Cyclic-di-GMP is a near-ubiquitous bacterial second messenger that is important in localized signal transmission during the control of various processes, including virulence and switching between planktonic and biofilm-based lifestyles. Cycl
Externí odkaz:
https://doaj.org/article/4cd8a7b44c2c4ca08405718a49654931
Autor:
Kornelia Przybyszewska, José A. Bengoechea, Joana Sá-Pessoa, Amy Dumigan, Laura Hobley, Filipe Nuno Vasconcelos, Christian G. Frank
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
mBio
Sá-Pessoa, J, Przybyszewska, K, Vasconcelos, F N, Dumigan, A, Frank, C G, Hobley, L & Bengoechea, J A 2020, ' Klebsiella pneumoniae Reduces SUMOylation To Limit Host Defense Responses ', mBio, vol. 11, no. 5 . https://doi.org/10.1128/mBio.01733-20
mBio
Sá-Pessoa, J, Przybyszewska, K, Vasconcelos, F N, Dumigan, A, Frank, C G, Hobley, L & Bengoechea, J A 2020, ' Klebsiella pneumoniae Reduces SUMOylation To Limit Host Defense Responses ', mBio, vol. 11, no. 5 . https://doi.org/10.1128/mBio.01733-20
Klebsiella pneumoniae has been singled out as an urgent threat to human health due to the increasing isolation of strains resistant to “last-line” antimicrobials, narrowing the treatment options against Klebsiella infections. Unfortunately, at pr
Autor:
Amy Dumigan, Joana Sá-Pessoa, José A. Bengoechea, Kornelia Przybyszewska, Christian G. Frank, Laura Hobley, Filipe Nuno Vasconcelos
Klebsiella pneumoniae is an important cause of multidrug resistant infections worldwide. Understanding the virulence mechanisms of K. pneumoniae is a priority and timely to design new therapeutics. Here we demonstrate that K. pneumoniae limits the SU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30fb9324bb1c8e723297f778fe235de6
https://doi.org/10.1101/2020.06.29.179275
https://doi.org/10.1101/2020.06.29.179275
Autor:
David S. Milner, Michelle Baker, Jan-Ulrich Kreft, Jamie Twycross, Jess Tyson, R. Elizabeth Sockett, Rob Till, Laura Hobley, Andreas Leidenroth, Michael J. Capeness, Robert J. Atterbury, J. Kimberley Summers, Ian F. Connerton, Stephanie Gray, Amy Stroud, Carey Lambert
Bacteria are preyed upon by diverse microbial predators, including bacteriophage and predatory bacteria, such as Bdellovibrio bacteriovorus While bacteriophage are used as antimicrobial therapies in Eastern Europe and are being applied for compassion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e0616efe6e64b21249c34bd749e2fa
https://doi.org/10.1128/jb.00629-19
https://doi.org/10.1128/jb.00629-19
Autor:
Laura Hobley, Chih-Yu Hsu, Nicola R. Stanley-Wall, James Abbott, Lynne S. Cairns, Conor P. O'Byrne
Publikováno v:
Journal of Bacteriology
Biofilms are an important mode of growth in many settings. Here, we looked at small differences in the genomes of the bacterium Listeria monocytogenes isolate EGDe and used them to find out how biofilms form. This important fundamental information ma