Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Laura H. Engelke"'
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
Abstract Background Widely established targeted therapies directed at triple negative breast cancer (TNBC) are missing. Classical chemotherapy remains the systemic treatment option. Cisplatin has been tested in TNBC but bears the disadvantage of resi
Externí odkaz:
https://doaj.org/article/bf4c7dea0a084108a9aef96fd9f60cf9
Autor:
Laura H. Engelke, Chenyin Wang, David Bickel, Peter Proksch, Alexandra Hamacher, Holger Gohlke, Matthias U. Kassack, Marian Frank
Publikováno v:
Bioorganicmedicinal chemistry. 27(19)
Platinum compounds are the first-line therapy for many types of cancer. However, drug resistance has frequently been reported for and is a major limitation of platinum-based chemotherapy in the clinic. In the current study, we examined the anti-tumor
Publikováno v:
Journal of Cancer
Purpose. Several studies have shown that natural compounds like resveratrol or ellagic acid have anticancer and antioxidant properties and can stimulate apoptosis in many cancer cell lines. The aim of this study was to elucidate if resveratrol or ell
Publikováno v:
BMC Cancer
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
Background Widely established targeted therapies directed at triple negative breast cancer (TNBC) are missing. Classical chemotherapy remains the systemic treatment option. Cisplatin has been tested in TNBC but bears the disadvantage of resistance de
Autor:
Christoph Janiak, Alexandra Hamacher, Richard Sawadogo, Stefanie Scheu, Peter Proksch, Amal H. Aly, Sebastian Wesselborg, Tibor Kurtán, Björn Stork, David Rönsberg, Philip Böhler, Attila Mándi, Matthias U. Kassack, Wenhan Lin, Abdessamad Debbab, Victor Wray, Vera Vasylyeva, Laura H. Engelke, Marc Diederich
Publikováno v:
The Journal of organic chemistry. 78(24)
Four tetrahydroxanthone dimers (1-4) and four biogenetically related monomers (5-8), including the new derivatives 4-6, were isolated from the endophyte Phomopsis longicolla. The absolute configurations of 2-4 were established for the first time by T