Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Laura Griewahn"'
Autor:
Laura Griewahn, Madeleine Müller, Lukas Peintner, Manuela Wissler, Martina Weiss, Prisca Brauns-Schubert, Ramin Massoumi, Christoph Borner, Olaf Groß, Monica Yabal, Céline Charvet, Ulrich Maurer
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111961- (2023)
Summary: SPATA2 mediates the recruitment of CYLD to immune receptor complexes by bridging the interaction of CYLD with the linear ubiquitylation assembly complex (LUBAC) component HOIP. Whether SPATA2 exhibits functions independently of CYLD is uncle
Externí odkaz:
https://doaj.org/article/e86bc9e4cce94274b37f594cfa34c61e
Autor:
Swantje C. Haeger, Khalaf Kridin, Mario Pieper, Laura Griewahn, Falk Nimmerjahn, Detlef Zillikens, Peter König, Ralf J. Ludwig, Jennifer E. Hundt
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Epidermolysis bullosa acquisita (EBA) is a subepidermal autoimmune bullous disease caused by autoantibodies targeting type VII collagen (COL7). It is characterized by inflammation and subepidermal blistering mainly through immune complex (IC)-mediate
Externí odkaz:
https://doaj.org/article/c72d71026f3e44a0af9970c7386dfbe0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Pro-inflammatory signaling pathways, induced by pathogens, tissue damage or cytokines, depend on the ubiquitylation of various subunits of receptor signaling complexes, controlled by ubiquitin ligases and deubiquitinases. Ubiquitylation sets the stag
Externí odkaz:
https://doaj.org/article/278787d258514724bf541573948ca374