Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Laura Girola"'
Autor:
Giacomina Rossi, Orso Bugiani, Fabrizio Tagliavini, Nadia Angeretti, Elisa Peressini, Enzio Ragg, Tazeen Awan, B. Canciani, Luca De Gioia, Lidia Giampaolo, Gianluigi Forloni, Mario Salmona, Laura Colombo, Laura Girola
Publikováno v:
Journal of Molecular Biology. 300:1309-1322
Prion diseases are characterized by the accumulation of altered forms of the prion protein (termed PrPSc) in the brain. Unlike the normal protein, PrPSc isoforms have a high content of β-sheet secondary structure, are protease-resistant, and form in
Autor:
Nadia Angeretti, Gianluigi Forloni, Mario Salmona, Giorgio Poli, Maria Grazia Bruzzone, Laura Colombo, Selina Iussich, Fabrizio Tagliavini, Orso Bugiani, Laura Farina, Giorgio Giaccone, Giacomina Rossi, James W. Ironside, Maria Caramelli, Lucia Limido, Tazeen Awan, Laura Girola, Ilaria Bertani
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(16)
Prion diseases are transmissible neurodegenerative disorders of humans and animals for which no effective treatment is available. Conformationally altered, protease-resistant forms of the prion protein (PrP) termed PrP Sc are critical for disease tra
Publikováno v:
Neurobiology of Aging. 21:242
Publikováno v:
FEBS Letters. (3):404-407
Cerebral deposition of beta-amyloid is a major neuropathological feature in Alzheimer's disease. Here we show that tetracyclines, tetracycline and doxycycline, classical antibiotics, exhibit anti-amyloidogenic activity. This capacity was determined b