Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Laura Geil"'
Autor:
Fuh-Mei Duh, Laura Geil, Ulla Bengtsson, Michael I. Lerman, Eric J. Stanbridge, Igor Kuzmin, Hai-Yan Ge
Publikováno v:
Oncogene. 18:5672-5679
Several tumor suppressor genes were shown to be inactivated by a process involving aberrant de novo methylation of their GC-rich promoters which is usually associated with transcriptional repression. The mechanisms underlying this process are poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0501a93381ad26b2de37f3869a6842f
https://doi.org/10.1038/sj.onc.1202959
https://doi.org/10.1038/sj.onc.1202959
Autor:
Gunamani Sithanandam, Farida Latif, Fuh-Mei Duh, Ricardo Bernal, Ute Smola, Hua Li, Igor Kuzmin, Viktor Wixler, Laura Geil, Sadeep Shrestha, Patricia A. Lloyd, Scott Bader, Yoshitaka Sekido, Kenneth D. Tartof, Vladimir I. Kashuba, Eugene R. Zabarovsky, Michael Dean, George Klein, Michael I. Lerman, John D. Minna, Ulf R. Rapp, Rando Allikmets
Publikováno v:
Scopus-Elsevier
NotI linking clones, localized to the human chromosome 3p21.3 region and homozygously deleted in small cell lung cancer cell lines NCI-H740 and NCI-H1450, were used to search for a putative tumor suppressor gene(s). One of these clones, NL1G210, dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bd55840b44b3cb54b9eefe3c8ca9ae
https://doi.org/10.1128/mcb.16.3.868
https://doi.org/10.1128/mcb.16.3.868
Autor:
Michael I. Lerman, Fumio Matsumura, W. Marston Linehan, James R. Gnarra, Thomas Stackhouse, Fuh-Mei Duh, Laura Geil, Yongkai Weng, D. Roxanne Duan, Farida Latif, William S. Modi
Publikováno v:
DNA and Cell Biology. 13:821-827
cDNA clones having extensive sequence identity with the sea urchin fascin and the Drosophila singed gene products were isolated from a human teratocarcinoma cDNA library. The human homolog, termed hsn, is a single-copy gene that was localized to huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd0a6b92ba2031042216101c9e01d9a
https://doi.org/10.1089/dna.1994.13.821
https://doi.org/10.1089/dna.1994.13.821
Autor:
George Klein, Vladimir I. Kashuba, A.I. Protopopov, John D. Minna, Eric J. Stanbridge, Fuli Wang, Eugene R. Zabarovsky, Laura Geil, Eleonora A. Braga, Jingfeng Li, Igor Kuzmin, Fuh Mei Duh, Klas Haraldson, Michael I. Lerman
Publikováno v:
Cancer research. 64(18)
Initial analysis identified the NPRL2/G21 gene located in 3p21.3C, the lung cancer region, as a strong candidate tumor suppressor gene. Here we provide additional evidence of the tumor suppressor function of NPRL2/G21. The gene has highly conserved h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b52d6ef85e72351735f74c520b96bb1
https://pubmed.ncbi.nlm.nih.gov/15374952
https://pubmed.ncbi.nlm.nih.gov/15374952
Autor:
Igor Kuzmin, Victor V. Lobanenkov, Tiziana Cavinato, Laura Geil, Michael I. Lerman, Dmitry Loukinov, Lauren Gibson
Publikováno v:
Journal of molecular biology. 346(2)
Immune responses to invading pathogens are mediated largely through a family of transmembrane Toll-like receptors and modulated by a number of downstream effectors. In particular, a family of four interleukin 1 receptor-associated kinases (IRAK) regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6217868131182c3bcadc5d2b760de3be
https://pubmed.ncbi.nlm.nih.gov/15670593
https://pubmed.ncbi.nlm.nih.gov/15670593
Autor:
Igor, Kuzmin, Limin, Liu, Reinhard, Dammann, Laura, Geil, Eric J, Stanbridge, Sharon P, Wilczynski, Michael I, Lerman, Gerd P, Pfeifer
Publikováno v:
Cancer research. 63(8)
Recently, we have identified a new putative tumor suppressor gene, RASSF1A (Ras association domain family 1A gene), located at human chromosome 3p21.3, the segment that is often lost in many types of human cancers. The RASSF1A promoter was shown to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::408d0590abb7713bd99ce1b6fcd59481
https://pubmed.ncbi.nlm.nih.gov/12702579
https://pubmed.ncbi.nlm.nih.gov/12702579
Autor:
Igor, Kuzmin, John W, Gillespie, Alexei, Protopopov, Laura, Geil, Koen, Dreijerink, Youfeng, Yang, Cathy D, Vocke, Fuh-Mei, Duh, Eugene, Zabarovsky, John D, Minna, Johng S, Rhim, Michael R, Emmert-Buck, W Marston, Linehan, Michael I, Lerman
Publikováno v:
Cancer research. 62(12)
We analyzed expression status of the recently identified tumor suppressor geneRASSF1A in primary prostate carcinomas and in prostate cell lines. We found complete methylation of the RASSF1A promoter in 63% of primary microdissected prostate carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28135f317097605ddd24c2ddfe0b0b0d
https://pubmed.ncbi.nlm.nih.gov/12067994
https://pubmed.ncbi.nlm.nih.gov/12067994
Autor:
Angeloni, Debora, Alla, Ivanova, Bert, Zbar, Fuh Mei Duh, Ming Hui Wei, Laura, Geil, Igor, Kuzmin, Sergei, Ivanov, Michael, Lerman, Donia, Macartney, Sofia, Honorio, Eamonn, Maher, Farida, Latif, Vladimir, Kashuba, Alexei, Protopopov, Jingfeng, Li, George, Klein, Eugene, Zabarovsky, Yoshitaka, Sekido, Scott, Bader, David, Burbee, Kwun, Fong, Eva, Forgacs, Boning, Gao, Harold, Garner, Adi, Gazdar, Luc, Girard, Craig, Kamibayashi, Masashi, Kondo, Ashwini, Pande, Alex, Persemlidis, Vivek, Ramalingam, Dwight, Randle, Yoshio, Tomizawa, Arvind, Virmani, Ivan, Wistuba, Grace, Zeng, John, Minna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3729::567d984abb25a9d17893cd154261eed0
http://hdl.handle.net/11382/302755
http://hdl.handle.net/11382/302755
Autor:
Eric J. Stanbridge, Svetlana Pack, Ming Hui Wei, Bruce E. Johnson, Sergey Ivanov, Michael I. Lerman, Laura Geil, Igor Kuzmin
To discover genes involved in von Hippel-Lindau (VHL)-mediated carcinogenesis, we used renal cell carcinoma cell lines stably transfected with wild-type VHL-expressing transgenes. Large-scale RNA differential display technology applied to these cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da92653f87e15cd71be6b23efe724c2b
https://europepmc.org/articles/PMC22876/
https://europepmc.org/articles/PMC22876/
Autor:
J. T. Feltis, Hiltrud Brauch, Gladys Glenn, C. Casadevall, McClellan M. Walther, Stefan Storkel, Thomas Stackhouse, Irina A. Lubensky, Ulf S.R. Bergerheim, C. J. M. Lips, Abirami Chidambaram, L. Slife, Peter L. Choyke, Rando Allikmets, B. Zbar, Holger Moch, Stéphane Richard, Lap-Chee Tsui, W.M. Linehan, Laura S. Schmidt, Zhengping Zhuang, Michael Dean, Jochen Decker, J. Lipan, M. Bernues, Fuh Mei Duh, Michael I. Lerman, A. Zamarron, Laura Geil, G. Niehans, Mary Lou Orcutt, Takeshi Kishida, Stephen W. Scherer, M. D. Hughson, F. Chen
Publikováno v:
Nature genetics. 16(1)
Hereditary papillary renal carcinoma (HPRC) is a recently recognized form of inherited kidney cancer characterized by a predisposition to develop multiple, bilateral papillary renal tumours. The pattern of inheritance of HPRC is consistent with autos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef07a943329c273cbab5ba5bd4649a8
https://pubmed.ncbi.nlm.nih.gov/9140397
https://pubmed.ncbi.nlm.nih.gov/9140397