Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Laura Gallot"'
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Akademický článek
Selective blockade of Cav1.2 (α1C) versus Cav1.3 (α1D) L-type calcium channels by the black mamba toxin calciseptine
Autor: Pietro Mesirca, Jean Chemin, Christian Barrère, Eleonora Torre, Laura Gallot, Arnaud Monteil, Isabelle Bidaud, Sylvie Diochot, Michel Lazdunski, Tuck Wah Soong, Stéphanie Barrère-Lemaire, Matteo E. Mangoni, Joël Nargeot
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract L-type voltage-gated calcium channels are involved in multiple physiological functions. Currently available antagonists do not discriminate between L-type channel isoforms. Importantly, no selective blocker is available to dissect the role o
Externí odkaz: https://doaj.org/article/2ab832a282b64fedbaeb690c44acc317
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2
Akademický článek
Heart rate reduction after genetic ablation of L-type Cav1.3 channels induces cardioprotection against ischemia-reperfusion injury
Autor: Viviana Delgado-Betancourt, Kroekkiat Chinda, Pietro Mesirca, Christian Barrère, Aurélie Covinhes, Laura Gallot, Anne Vincent, Isabelle Bidaud, Sarawut Kumphune, Joël Nargeot, Christophe Piot, Kevin Wickman, Matteo Elia Mangoni, Stéphanie Barrère-Lemaire
Publikováno v: Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundAcute myocardial infarction (AMI) is the major cause of cardiovascular mortality worldwide. Most ischemic episodes are triggered by an increase in heart rate, which induces an imbalance between myocardial oxygen delivery and consumption. De
Externí odkaz: https://doaj.org/article/a970e246abbf4797bacbe5953a306b1b
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3
Anti-apoptotic peptide for long term cardioprotection in a mouse model of myocardial ischemia–reperfusion injury
Autor: S. Barrere-Lemaire, Anne Vincent, Christian Barrère, Bernard Lebleu, Christophe Piot, Prisca Boisguerin, Joël Nargeot, Aurélie Covinhes, Laura Gallot, Catherine Sportouch
Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-75154-x⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-75154-x⟩
Reperfusion therapy during myocardial infarction (MI) leads to side effects called ischemia–reperfusion (IR) injury for which no treatment exists. While most studies have targeted the intrinsic apoptotic pathway to prevent IR injury with no success
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac8b9a94382c6fc0ff74df04e94012f
https://hal.archives-ouvertes.fr/hal-02996282
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4
Cardioprotective effect of the TD anti-apoptotic peptide: Study of the mechanisms of action
Autor: Anne Vincent, Christian Barrère, Aurélie Covinhes, Laura Gallot, Christophe Piot, C. Fernandez-Rico, Stéphanie Barrère-Lemaire, Joël Nargeot, Bernard Lebleu, Prisca Boisguerin
Publikováno v: Archives of Cardiovascular Diseases Supplements
Printemps de la Cardiologie
Printemps de la Cardiologie, Oct 2020, Grenoble (E-meeting), France. Elsevier/French Society of Cardiology, 12 (2-4), pp.228-229, 2020, Archives of Cardiovascular Disease Supplements. ⟨10.1016/j.acvdsp.2020.03.072⟩
International audience; Introduction: Apoptosis is a main contributor of reperfusion injury after myocardial infarction. In a previous study, we evidenced the cardioprotective effect of a synthetic peptide (TD) able to interfere with FAS-DAXX interac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb0eb7b85be3120ed552a28b1632cc8
https://hal.archives-ouvertes.fr/hal-03015716
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5
Cardiac mGluR1 metabotropic receptors in cardioprotection
Autor: Stéphanie Barrère-Lemaire, Anne Vincent, Christophe Piot, Christian Barrère, Joël Nargeot, Benoit Lattuca, Viviana Delgado-Betancourt, Laura Gallot, Catherine Sportouch, Aurélie Covinhes, Kamila Solecki, Prisca Boisguerin
Publikováno v: Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2017, 113 (6), pp.644--655. ⟨10.1093/cvr/cvx024⟩
Aims In a previous study using a genome-wide microarray strategy, we identified metabotropic glutamate receptor 1 (mGluR1) as a putative cardioprotective candidate in ischaemic postconditioning (PostC). In the present study, we investigated the role
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfaf9365ac8a207d4d0d71349cedf10
https://doi.org/10.1093/cvr/cvx024
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6
Cardioprotective effects of a synthetic peptide targeting the extrinsic apoptotic pathway in a mouse model of ischemia-reperfusion
Autor: Muriel Busson, Anne Vincent, Christophe Piot, Christian Barrère, Joël Nargeot, Stéphanie Barrère-Lemaire, Bernard Lebleu, Aurélie Covinhes, Laura Gallot, Prisca Boisguerin
Publikováno v: Archives of cardiovascular diseases
Archives of cardiovascular diseases, Elsevier/French Society of Cardiology, 2019, 11 (2), pp.211. ⟨10.1016/j.acvdsp.2019.02.065⟩
Introduction Apoptosis is a main contributor of myocardial reperfusion injury during acute infarction. In a previous study, we showed that reperfusion injury was mediated by the FAS-dependent apoptotic signal mobilizing the DAXX (death-associated pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e139dfddaa9a34e50cbafb906daf51
https://hal.archives-ouvertes.fr/hal-02404659
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7
Acute and long-term cardioprotective effects of the Traditional Chinese Medicine MLC901 against myocardial ischemia-reperfusion injury in mice
Autor: Christophe Piot, Catherine Heurteaux, Soulit Thoumala, Joël Nargeot, Christian Barrère, Laura Gallot, Anne Vincent, Michel Lazdunski, Stéphanie Barrère-Lemaire, Aurélie Covinhes
Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), ⟨10.1038/s41598-017-14822-x⟩
Scientific Reports, 2017, 7 (1), pp.14701. ⟨10.1038/s41598-017-14822-x⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
MLC901, a traditional Chinese medicine containing a cocktail of active molecules, both reduces cerebral infarction and improves recovery in patients with ischemic stroke. The aim of this study was to evaluate the acute and long-term benefits of MLC90
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6323b2f69ddd382e1845cc549d971e86
https://pubmed.ncbi.nlm.nih.gov/29089640
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