Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Laura Gallego"'
Autor:
Alberto Torres-Zurita, Lucía Vázquez-Montero, Laura Gallego-López, María Dolores Mediano-Rambla, Luis de la Cruz-Merino
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Nowadays, immune checkpoint inhibitors (ICI) have become the cornerstone of treatment for many tumors, either as monotherapy or in combination with other therapies. However, these drugs are associated with several new side effects that need early det
Externí odkaz:
https://doaj.org/article/e7f8dded05b14850936d2a0a4f5514ca
Autor:
Fabrice B. R. Parmentier, Laura Gallego, Antonia Micucci, Alicia Leiva, Pilar Andrés, Murray T. Maybery
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Evidence shows that participants performing a continuous visual categorization task respond slower following the presentation of a task-irrelevant sound deviating from an otherwise repetitive or predictable auditory context (deviant sound am
Externí odkaz:
https://doaj.org/article/e80c626952d843389fe7d06a3a0c621f
Autor:
Sergio Ramos, Alba Vicente-Blázquez, Marta López-Rubio, Laura Gallego-Yerga, Raquel Álvarez, Rafael Peláez
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17474 (2023)
Antimitotic agents are one of the more successful types of anticancer drugs, but they suffer from toxicity and resistance. The application of approved drugs to new indications (i.e., drug repurposing) is a promising strategy for the development of ne
Externí odkaz:
https://doaj.org/article/11cd78c01a504b259a39ab2261a417f3
Autor:
Rosa M. Moreno Rodríguez, Beatriz Solas Gómez, Laura Gallego Marcuello, Maria del Carmen Diaz Martinez, Encarnacion Fernández del Palacio, Andrés Santiago-Sáez
Publikováno v:
Healthcare, Vol 11, Iss 19, p 2605 (2023)
Background: Fall prevention is an important indicator of the quality of patient care. Prevention includes the use of adequate footwear. Our objective is to determine the differences in the number of falls between patients with “adequate footwear”
Externí odkaz:
https://doaj.org/article/bbabd4fc15b64dadbcb0af3c7bb3eeae
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11093 (2023)
Increasing awareness of the structure of microtubules has made tubulin a relevant target for the research of novel chemotherapies. Furthermore, the particularly high sensitivity of glioblastoma multiforme (GBM) cells to microtubule disruption could o
Externí odkaz:
https://doaj.org/article/e8a74246d98043ae9fe89b3ba0bc4f2f
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1698 (2023)
The design of colchicine site ligands on tubulin has proven to be a successful strategy to develop potent antiproliferative drugs against cancer cells. However, the structural requirements of the binding site endow the ligands with low aqueous solubi
Externí odkaz:
https://doaj.org/article/b9b06ce8bf9b4492bb9e9253040d8cbf
Autor:
Laura Gallego-Yerga, Rodrigo Ochoa, Isaías Lans, Carlos Peña-Varas, Melissa Alegría-Arcos, Pilar Cossio, David Ramírez, Rafael Peláez
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4360-4372 (2021)
Tubulin is a well-validated target for herbicides, fungicides, anti-parasitic, and anti-tumor drugs. Many of the non-cancer tubulin drugs bind to its colchicine site but no colchicine-site anticancer drug is available. The colchicine site is composed
Externí odkaz:
https://doaj.org/article/2267eec464c643dea14b7911f56fac0d
Publikováno v:
Resources, Vol 11, Iss 3, p 32 (2022)
The development of this research work seeks to determine the mechanical behavior of the compacted mixture of pine sawdust and rice husk by varying the mass percentages of these biomasses obtained in briquettes, with the purpose of being marketed. The
Externí odkaz:
https://doaj.org/article/245324c5907d468e8edc9a553f61bbd1
Autor:
Diana Guavita-Navarro, Laura Gallego-Cardona, Ana María Arredondo, Hector Cubides, Jairo Cajamarca-Barón, Claudia Ibáñez, Alejandro Escobar, Adriana Rojas-Villarraga
Publikováno v:
Journal of Translational Autoimmunity, Vol 4, Iss , Pp 100133- (2021)
Background: /Objective: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with a wide range of clinical manifestations. The latest classification criteria, EULAR/ACR 2019, have not been validated in a Latin American population of
Externí odkaz:
https://doaj.org/article/202302a592584ea292744613a188ce68
Autor:
Laura Gallego López, Aurora Díaz Valdecantos, César Carrascosa Rosillo, Nuria Miranda Balbuena
Publikováno v:
REC: Interventional Cardiology, Vol 1, Iss 2, Pp 142-143 (2019)
Sr. Editor: Se presenta el caso de una mujer de 65 años sin alergias conocidas a medicamentos y con antecedentes personales cardiológicos de fibrilación auricular, en tratamiento anticoagulante con warfarina, y con polivalvulopatía reumática con
Externí odkaz:
https://doaj.org/article/653a85c4d0ba4378a54dd869c1ca4466