Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Laura Figuerola"'
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Akademický článek
Design, Synthesis, and Pharmacological Evaluation of Novel Quinolone Aryl Sulfonamide Derivatives as Potent GPR55 Antagonists
Autor: Paula Morales, Laura Figuerola-Asencio, Dow H. Hurst, Pingwei Zhao, Mary E. Abood, Patricia H. Reggio, Nadine Jagerovic
Publikováno v: Proceedings, Vol 22, Iss 1, p 92 (2019)
Docking studies of identified GPR55 ligands using a GPR55 inactive state model allow rationalizing key structural features involved in ligand–receptor binding. On this molecular basis, we have designed novel quinolone sulfonamide derivatives with o
Externí odkaz: https://doaj.org/article/2630e8776f5d4776bbd5423c44a9f3b6
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4
Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure-Activity Relationship
Autor: Laura Figuerola-Asencio, Paula Morales, Pingwei Zhao, Dow P. Hurst, Sommayah S. Sayed, Katsuya L. Colón, María Gómez-Cañas, Javier Fernández-Ruiz, Mitchell P. Croatt, Patricia H. Reggio, Mary E. Abood, Nadine Jagerovic
GPR55 is an orphan G-protein coupled receptor involved in various pathophysiological conditions. However, there are only a few noncannabinoid GPR55 ligands reported so far. The lack of potent and selective GPR55 ligands precludes a deep exploration o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae463e4b82c805a8a62fc3966e760b0e
http://hdl.handle.net/10261/309060
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5
LIGAND-BASED DRUG DESIGN APPROACHES FOR THE IDENTIFICATION OF NOVEL GPR55 MODULATORS
Autor: Paula Morales, Dow P. Hurst, Mary E. Abood, Patricia H. Reggio, Laura Figuerola-Asencio, Pingwei Zhao, Nadine Jagerovic
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
GPR55 is an orphan Class A G-protein coupled receptor that recognizes a sub-set of cannabinoid CB1 and CB2 ligands, suggesting that GPR55 could belong to the endocannabinoid system. Lysophosphatidylinositol (LPI) has been proposed to be endogenous li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79368c594b6e68650611fa45ae187c4
http://hdl.handle.net/10261/232389
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6
Design, Synthesis, and Pharmacological Evaluation of Novel Quinolone Aryl Sulfonamide Derivatives as Potent GPR55 Antagonists
Autor: Laura Figuerola-Asencio, Pingwei Zhao, Paula Morales, Dow H. Hurst, Nadine Jagerovic, Mary E. Abood, Patricia H. Reggio
Publikováno v: Proceedings, Vol 22, Iss 1, p 92 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Docking studies of identified GPR55 ligands using a GPR55 inactive state model allow rationalizing key structural features involved in ligand–receptor binding. On this molecular basis, we have designed novel quinolone sulfonamide derivatives with o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54c972a666241017442ce8744075502
http://hdl.handle.net/10261/190079
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7
New Methods for the Synthesis of Cannabidiol Derivatives
Autor: Ana, Lago-Fernandez, Vanessa, Redondo, Laura, Hernandez-Folgado, Laura, Figuerola-Asencio, Nadine, Jagerovic
Publikováno v: Methods in enzymology. 593
Cannabidiol (CBD) is one of the most abundant components isolated from Cannabis sativa. However, CBD is a nonpsychotropic phytocannabinoid. In the last decade, there has been a growing interest in its therapeutic effects. This is why this natural pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::84dfc4657e3ec3b5c7e132bd578bf501
https://pubmed.ncbi.nlm.nih.gov/28750806
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8
New Methods for the Synthesis of Cannabidiol Derivatives
Autor: Laura Hernandez-Folgado, Ana Lago-Fernandez, Laura Figuerola-Asencio, Vanessa Redondo, Nadine Jagerovic
Cannabidiol (CBD) is one of the most abundant components isolated from Cannabis sativa. However, CBD is a nonpsychotropic phytocannabinoid. In the last decade, there has been a growing interest in its therapeutic effects. This is why this natural pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0aab36ce3eeb960586304a639fa33c1
https://doi.org/10.1016/bs.mie.2017.05.006
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9
Accounting for life-history strategies and timescales in marine restoration
Autor: Ignasi Montero-Serra, Joaquim Garrabou, Daniel F. Doak, Laura Figuerola, Bernat Hereu, Jean-Baptiste Ledoux, Cristina Linares
Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Conservation Letters
Conservation Letters, 2017, 7 (1), ⟨10.1111/conl.12341⟩
Dipòsit Digital de la UB
Universidad de Barcelona
Conservation Letters, Wiley, 2017, 7 (1), ⟨10.1111/conl.12341⟩
Digital.CSIC. Repositorio Institucional del CSIC
9 pages, 5 figures, supporting information https://doi.org/10.1111/conl.12341
Understanding the drivers of restoration success is a central issue for marine conservation. Here, we explore the role of life‐history strategies of sessile marine s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::17990b4bb3130fa5e335864f26d8551e
http://hdl.handle.net/2445/120204
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