Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Laura Fici"'
Autor:
Emilia Luca, Laura Fici, Anna Ronchi, Ferdinando Marandino, Esther Diana Rossi, Maria Emiliana Caristo, Pasqualino Malandrino, Marco Russo, Alfredo Pontecorvi, Riccardo Vigneri, Fabiola Moretti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-9 (2017)
Abstract Background Epidemiologic data in volcanic areas suggest that environmental factors might be involved in the increase of thyroid cancer (TC) incidence. Recent reports indicate that several heavy metals and metalloids are increased in volcanic
Externí odkaz:
https://doaj.org/article/9af59c8d9ce34d55adc8710ef2f2092c
Autor:
Fabiola Moretti, Antonio Macchiarulo, Jean Christophe Marine, Alfredo Pontecorvi, Roberto Pellicciari, Giulia Piaggio, Mara D'Onofrio, Maurizio Fanciulli, Tiziana Bruno, Rossella Brandi, Laura Fici, Marianna Buttarelli, Emanuela Teveroni, Fulvio Florenzano, Ivan Arisi, Isabella Manni, Nicola Giacchè, Alice Coletti, Rossella Lucà, Francesca Mancini, Marsha Pellegrino
Supplementary Figures S1-9, Tables S1 and 2. Supplementary Figure S1: Analysis of p53 ubiquitination and binding Supplementary Figure S2: Pep3 activity in human tumor cell lines Supplementary Figure S3: Pep3 activity in untransformed cells Supplement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f412cf386837aee8ea282366fd89e0
https://doi.org/10.1158/0008-5472.22405989.v1
https://doi.org/10.1158/0008-5472.22405989.v1
Autor:
Giovanni Scambia, Maria Pia Gentileschi, Alessandra Ciucci, Emanuela Teveroni, Alessandro Apollo, Giorgia di Blasio, Marianna Buttarelli, Francesca Mancini, Valentina Monteleone, Gian Franco Zannoni, Marsha Pellegrino, Fabiola Moretti, Alfredo Pontecorvi, Silvia Maiullari, Rossella Lucà, Laura Fici, Germana Ciolli, Isabella Manni, Daniela Gallo
Publikováno v:
Cancers (Basel) 11 (2019). doi:10.3390/cancers11091349
info:cnr-pdr/source/autori:Lucà, Rossella; Blasio, Giorgia Di; Gallo, Daniela; Monteleone, Valentina; Manni, Isabella; Fici, Laura; Buttarelli, Marianna; Ciolli, Germana; Pellegrino, Marsha; Teveroni, Emanuela; Maiullari, Silvia; Ciucci, Alessandra; Apollo, Alessandro; Mancini, Francesca; Gentileschi, Maria Pia; Zannoni, Gian Franco; Pontecorvi, Alfredo; Scambia, Giovanni; Moretti, Fabiola/titolo:Estrogens counteract platinum-chemosensitivity by modifying the subcellular localization of MDM4/doi:10.3390%2Fcancers11091349/rivista:Cancers (Basel)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Cancers
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1349 (2019)
info:cnr-pdr/source/autori:Lucà, Rossella; Blasio, Giorgia Di; Gallo, Daniela; Monteleone, Valentina; Manni, Isabella; Fici, Laura; Buttarelli, Marianna; Ciolli, Germana; Pellegrino, Marsha; Teveroni, Emanuela; Maiullari, Silvia; Ciucci, Alessandra; Apollo, Alessandro; Mancini, Francesca; Gentileschi, Maria Pia; Zannoni, Gian Franco; Pontecorvi, Alfredo; Scambia, Giovanni; Moretti, Fabiola/titolo:Estrogens counteract platinum-chemosensitivity by modifying the subcellular localization of MDM4/doi:10.3390%2Fcancers11091349/rivista:Cancers (Basel)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Cancers
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1349 (2019)
Estrogen activity towards cancer-related pathways can impact therapeutic intervention. Recent omics data suggest possible crosstalk between estrogens/gender and MDM4, a key regulator of p53. Since MDM4 can either promote cell transformation or enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f893d894f92128c0b1601f1bf909dadb
http://www.scopus.com/record/display.url?eid=2-s2.0-85073385969&origin=inward
http://www.scopus.com/record/display.url?eid=2-s2.0-85073385969&origin=inward
Autor:
Francesca Mancini, Rossella Lucà, Roberto Pellicciari, Nicola Giacchè, Marsha Pellegrino, Tiziana Bruno, Mara D'Onofrio, Ivan Arisi, Rossella Brandi, Laura Fici, Alfredo Pontecorvi, Antonio Macchiarulo, Isabella Manni, Jean-Christophe Marine, Marianna Buttarelli, Alice Coletti, Emanuela Teveroni, Fabiola Moretti, Giulia Piaggio, Fulvio Florenzano, Maurizio Fanciulli
Publikováno v:
Cancer research (Chic. Ill.) 75 (2015): 4560–4572. doi:10.1158/0008-5472.CAN-15-0439
info:cnr-pdr/source/autori:Pellegrino, Marsha; Mancini, Francesca; Luca, Rossella; Coletti, Alice; Giacche, Nicola; Manni, Isabella; Arisi, Ivan; Florenzano, Fulvio; Teveroni, Emanuela; Buttarelli, Marianna; Fici, Laura; Brandi, Rossella; Bruno, Tiziana; Fanciulli, Maurizio; D'Onofrio, Mara; Piaggio, Giulia; Pellicciari, Roberto; Pontecorvi, Alfredo; Marine, Jean Christophe; Macchiarulo, Antonio; Moretti, Fabiola/titolo:Targeting the MDM2%2FMDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy/doi:10.1158%2F0008-5472.CAN-15-0439/rivista:Cancer research (Chic. Ill.)/anno:2015/pagina_da:4560/pagina_a:4572/intervallo_pagine:4560–4572/volume:75
info:cnr-pdr/source/autori:Pellegrino, Marsha; Mancini, Francesca; Luca, Rossella; Coletti, Alice; Giacche, Nicola; Manni, Isabella; Arisi, Ivan; Florenzano, Fulvio; Teveroni, Emanuela; Buttarelli, Marianna; Fici, Laura; Brandi, Rossella; Bruno, Tiziana; Fanciulli, Maurizio; D'Onofrio, Mara; Piaggio, Giulia; Pellicciari, Roberto; Pontecorvi, Alfredo; Marine, Jean Christophe; Macchiarulo, Antonio; Moretti, Fabiola/titolo:Targeting the MDM2%2FMDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy/doi:10.1158%2F0008-5472.CAN-15-0439/rivista:Cancer research (Chic. Ill.)/anno:2015/pagina_da:4560/pagina_a:4572/intervallo_pagine:4560–4572/volume:75
Restoration of wild-type p53 tumor suppressor function has emerged as an attractive anticancer strategy. Therapeutics targeting the two p53-negative regulators, MDM2 and MDM4, have been developed, but most agents selectively target the ability of onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5394eea26cda0ad1c3bfa4f2ebcfab
https://doi.org/10.1158/0008-5472.can-15-0439
https://doi.org/10.1158/0008-5472.can-15-0439
Autor:
Laura Fici, Marco Russo, Pasqualino Malandrino, Fabiola Moretti, Maria Emiliana Caristo, Riccardo Vigneri, Esther Diana Rossi, Anna Ronchi, Alfredo Pontecorvi, Ferdinando Marandino, Emilia Luca
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of experimental & clinical cancer research (Online) 36 (2017). doi:10.1186/s13046-017-0543-z
info:cnr-pdr/source/autori:Luca E.; Fici L.; Ronchi A.; Marandino F.; Rossi E.D.; Caristo M.E.; Malandrino P.; Russo M.; Pontecorvi A.; Vigneri R.; Moretti F./titolo:Intake of Boron, Cadmium, and Molybdenum enhances rat thyroid cell transformation/doi:10.1186%2Fs13046-017-0543-z/rivista:Journal of experimental & clinical cancer research (Online)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:36
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-9 (2017)
Journal of experimental & clinical cancer research (Online) 36 (2017). doi:10.1186/s13046-017-0543-z
info:cnr-pdr/source/autori:Luca E.; Fici L.; Ronchi A.; Marandino F.; Rossi E.D.; Caristo M.E.; Malandrino P.; Russo M.; Pontecorvi A.; Vigneri R.; Moretti F./titolo:Intake of Boron, Cadmium, and Molybdenum enhances rat thyroid cell transformation/doi:10.1186%2Fs13046-017-0543-z/rivista:Journal of experimental & clinical cancer research (Online)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:36
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-9 (2017)
Background Epidemiologic data in volcanic areas suggest that environmental factors might be involved in the increase of thyroid cancer (TC) incidence. Recent reports indicate that several heavy metals and metalloids are increased in volcanic areas. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3559c6eeb3032f1010974fddb3c06068
http://europepmc.org/articles/PMC5455132
http://europepmc.org/articles/PMC5455132
Autor:
Emilia Luca, Rossella Lucà, Riccardo Masetti, Silvia Soddu, S. Xiong, G. Lozano, Alfredo Pontecorvi, Luisa Pieroni, Valentina Monteleone, Francesca Mancini, Fabiola Moretti, Andrea Urbani, Laura Fici
Publikováno v:
Oncogene (Basingstoke, Online) 35 (2016): 228–240. doi:10.1038/onc.2015.76
info:cnr-pdr/source/autori:Mancini F, Pieroni L, Monteleone V, Lucà R, Fici L, Luca L, Urbani A, Xiong S, Soddu S, Masetti R, Lozano G, Pontecorvi A, Moretti F./titolo:MDM4%2FHIPK2%2Fp53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response/doi:10.1038%2Fonc.2015.76/rivista:Oncogene (Basingstoke, Online)/anno:2016/pagina_da:228/pagina_a:240/intervallo_pagine:228–240/volume:35
Oncogene
info:cnr-pdr/source/autori:Mancini F, Pieroni L, Monteleone V, Lucà R, Fici L, Luca L, Urbani A, Xiong S, Soddu S, Masetti R, Lozano G, Pontecorvi A, Moretti F./titolo:MDM4%2FHIPK2%2Fp53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response/doi:10.1038%2Fonc.2015.76/rivista:Oncogene (Basingstoke, Online)/anno:2016/pagina_da:228/pagina_a:240/intervallo_pagine:228–240/volume:35
Oncogene
The p53 inhibitor, MDM4 (MDMX) is a cytoplasmic protein with p53-activating function under DNA damage conditions. Particularly, MDM4 promotes phosphorylation of p53 at Ser46, a modification that precedes different p53 activities. We investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa886410acf884c1204be867c8841783
http://hdl.handle.net/10807/94151
http://hdl.handle.net/10807/94151