Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura Fernandez Garcia-Agudo"'
Autor:
Manvendra Singh, Ying Zhao, Vinicius Daguano Gastaldi, Sonja M. Wojcik, Yasmina Curto, Riki Kawaguchi, Ricardo M. Merino, Laura Fernandez Garcia-Agudo, Holger Taschenberger, Nils Brose, Daniel Geschwind, Klaus-Armin Nave, Hannelore Ehrenreich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Recombinant human erythropoietin (rhEPO) has potent procognitive effects, likely hematopoiesis-independent, but underlying mechanisms and physiological role of brain-expressed EPO remained obscure. Here, we provide transcriptional hippocampa
Externí odkaz:
https://doaj.org/article/96efba9a694c49e598c5b30a2073b0e7
Autor:
Laura Fernandez Garcia-Agudo, Agnes A. Steixner-Kumar, Yasmina Curto, Nadine Barnkothe, Imam Hassouna, Sebastian Jähne, Umer Javed Butt, Katharina Grewe, Martin S. Weber, Kim Green, Silvio Rizzoli, Juan Nacher, Klaus-Armin Nave, Hannelore Ehrenreich
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109548- (2021)
Summary: In adult cornu ammonis hippocampi, erythropoietin (EPO) expression drives the differentiation of new neurons, independent of DNA synthesis, and increases dendritic spine density. This substantial brain hardware upgrade is part of a regulator
Externí odkaz:
https://doaj.org/article/42f27ee525b44a1987ebb71c0214859d
Autor:
Umer Javed Butt, Imam Hassouna, Laura Fernandez Garcia-Agudo, Agnes A. Steixner-Kumar, Constanze Depp, Nadine Barnkothe, Matthias R. Zillmann, Anja Ronnenberg, Viktoria Bonet, Sandra Goebbels, Klaus-Armin Nave, Hannelore Ehrenreich
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3164 (2021)
We previously introduced the brain erythropoietin (EPO) circle as a model to explain the adaptive ‘brain hardware upgrade’ and enhanced performance. In this fundamental circle, brain cells, challenged by motor-cognitive tasks, experience function
Externí odkaz:
https://doaj.org/article/4b9ec14957314d3b8d4633a066633bbe
Autor:
Manvendra Singh, Ying Zhao, Vinicius Daguano Gastaldi, Sonja M. Wojcik, Yasmina Curto, Riki Kawaguchi, Ricardo M. Merino, Laura Fernandez Garcia-Agudo, Holger Taschenberger, Nils Brose, Daniel Geschwind, Klaus-Armin Nave, Hannelore Ehrenreich
Recombinant human erythropoietin (rhEPO) has potent procognitive effects, hematopoiesis-independent, but underlying mechanisms and physiological role of brain-expressed EPO have remained obscure. Here, we provide encyclopedic transcriptional hippocam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d6f7a7ee8dd4bdf860dfdd49d5fa0de
https://doi.org/10.1101/2023.02.04.527116
https://doi.org/10.1101/2023.02.04.527116
Autor:
Hannelore Ehrenreich, Laura Fernandez Garcia-Agudo, Agnes A. Steixner-Kumar, Justus B. H. Wilke, Umer Javed Butt
Publikováno v:
Molecular Psychiatry
PrefaceExecutive functions, learning, attention, and processing speed are imperative facets of cognitive performance, affected in neuropsychiatric disorders. In clinical studies on different patient groups, recombinant human (rh) erythropoietin (EPO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45dc3c0459f960a46d9b431d430684dd
https://hdl.handle.net/21.11116/0000-000A-D652-821.11116/0000-000A-D654-6
https://hdl.handle.net/21.11116/0000-000A-D652-821.11116/0000-000A-D654-6
Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion
Autor:
Imam Hassouna, Felicia J. van der Flier, Martin S. Weber, Nadine Schopf, Sahab Arinrad, Laura Fernandez Garcia-Agudo, Hana Janova, Hannelore Ehrenreich, Anja Ronnenberg, Susann Boretius, Henrik Martens, Klaus-Armin Nave, Evan Balmuth, Lea E. Sendler, Martin Begemann, Agnes Steixner
Publikováno v:
The FASEB Journal. 33:8634-8647
Reduced expression of 2'-3′-cyclic nucleotide 3′-phosphodiesterase (Cnp) in humans and mice causes white matter inflammation and catatonic signs. These consequences are experimentally alleviated by...
Autor:
Laura Fernandez Garcia-Agudo, Umer Javed Butt, Imam Hassouna, Matthias R. Zillmann, Anja Ronnenberg, Constanze Depp, Hannelore Ehrenreich, Viktoria Bonet, Klaus-Armin Nave, Nadine Barnkothe, Sandra Goebbels, Agnes A. Steixner-Kumar
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 6
International Journal of Molecular Sciences, Vol 22, Iss 3164, p 3164 (2021)
International journal of molecular sciences.
Volume 22
Issue 6
International Journal of Molecular Sciences, Vol 22, Iss 3164, p 3164 (2021)
International journal of molecular sciences.
We previously introduced the brain erythropoietin (EPO) circle as a model to explain the adaptive ‘brain hardware upgrade’ and enhanced performance. In this fundamental circle, brain cells, challenged by motor-cognitive tasks, experience function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c7f498453ef49aebe8f97d77af4259
https://hdl.handle.net/21.11116/0000-000C-81F0-221.11116/0000-000C-81F2-0
https://hdl.handle.net/21.11116/0000-000C-81F0-221.11116/0000-000C-81F2-0
Autor:
Katharina Grewe, Juan Nacher, Laura Fernandez Garcia-Agudo, Kim N. Green, Hannelore Ehrenreich, Umer Javed Butt, Yasmina Curto, Agnes A. Steixner-Kumar, Martin S. Weber, Imam Hassouna, Sebastian Jähne, Klaus-Armin Nave, Nadine Barnkothe, Silvio O. Rizzoli
Publikováno v:
Cell Reports
Cell Reports, Vol 36, Iss 8, Pp 109548-(2021)
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Cell Reports, Vol 36, Iss 8, Pp 109548-(2021)
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
In adult cornu ammonis hippocampi, erythropoietin (EPO) expression drives the differentiation of new neurons,independent of DNA synthesis, and increases dendritic spine density. This substantial brain hardwareupgrade is part of a regulatory circle: d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c9d564df74ff1e7f3731ac81f51338
https://hdl.handle.net/21.11116/0000-000A-28F7-321.11116/0000-000A-28F9-1
https://hdl.handle.net/21.11116/0000-000A-28F7-321.11116/0000-000A-28F9-1
Autor:
Leonie Mohrmann, Kamilla W. Miskowiak, Ting Sun, Martin Hindermann, Ulli Bode, Matthias R. Zillmann, Anja Ronnenberg, Sahab Arinrad, Imam Hassouna, Laura Fernandez Garcia-Agudo, Umer Javed Butt, Stefan Bonn, Klaus-Armin Nave, Constanze Depp, Agnes A. Steixner-Kumar, Sandra Goebbels, Liane Wüstefeld, Nadine Schopf, Hannelore Ehrenreich, Dörthe M. Katschinski
Publikováno v:
Molecular Psychiatry
Physical activity and cognitive challenge are established non-invasive methods to induce comprehensive brain activation and thereby improve global brain function including mood and emotional well-being in healthy subjects and in patients. However, th
Autor:
Laura Fernandez, Garcia-Agudo, Hana, Janova, Lea E, Sendler, Sahab, Arinrad, Agnes A, Steixner, Imam, Hassouna, Evan, Balmuth, Anja, Ronnenberg, Nadine, Schopf, Felicia J, van der Flier, Martin, Begemann, Henrik, Martens, Martin S, Weber, Susann, Boretius, Klaus-Armin, Nave, Hannelore, Ehrenreich
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(7)
Reduced expression of 2'-3'-cyclic nucleotide 3'-phosphodiesterase (