Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Laura F. Su"'
Autor:
Chenfeng He, Michael J. Malone, Ben S. Wendel, Ke-Yue Ma, Daniel Del Alcazar, David B. Weiner, Philip L. De Jager, Perla M. Del Río-Estrada, Yuria Ablanedo-Terrazas, Gustavo Reyes-Terán, Laura F. Su, Ning Jiang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Follicular-helper T cells (TFH) are an essential arm of the adaptive immune system. Although TFH were first discovered through their ability to contribute to antibody affinity maturation through co-stimulatory interactions with B cells, new light has
Externí odkaz:
https://doaj.org/article/c4d8069c180c4d2caf8a7868ae973a89
Autor:
Daniel Del Alcazar, Yifeng Wang, Chenfeng He, Ben S. Wendel, Perla M. Del Río-Estrada, Jerome Lin, Yuria Ablanedo-Terrazas, Michael J. Malone, Stefany M. Hernandez, Ian Frank, Ali Naji, Gustavo Reyes-Terán, Ning Jiang, Laura F. Su
Publikováno v:
Cell Reports, Vol 28, Iss 12, Pp 3047-3060.e7 (2019)
Summary: CXCR5 is a key marker of follicular helper T (TFH) cells. Using primary lymph nodes (LNs) from HIV-infected patients, we identified a population of CXCR5− CD4+ T cells with TFH-cell-like features. This CXCR5− subset becomes expanded in s
Externí odkaz:
https://doaj.org/article/0d9e7649f1b04057af938988d3c462ca
Autor:
Pavol Zelina, Anna Aster de Ruiter, Christy Kolsteeg, Ilona van Ginneken, Harmjan R. Vos, Laura F. Supiot, Boudewijn M. T. Burgering, Frank J. Meye, Jan H. Veldink, Leonard H. van den Berg, R. Jeroen Pasterkamp
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-32 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease leading to motor neuron loss. Currently mutations in > 40 genes have been linked to ALS, but the contribution of many genes and genetic mutations to the ALS path
Externí odkaz:
https://doaj.org/article/4a977d03dfcc4c5eacc3e8ab78fc3e99
Identification of Human Antigen-Specific T Cells Using Class II MHC Tetramer Staining and Enrichment
Autor:
Yi-Gen, Pan, Laura F, Su
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2574
The development of peptide-major histocompatibility complex tetramers has enabled direct characterization and enumeration of antigen-specific T cells. However, the weaker interaction between class II tetramers and CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f61cbeb742e7247e090332abebecc77
https://pubmed.ncbi.nlm.nih.gov/36087197
https://pubmed.ncbi.nlm.nih.gov/36087197
Autor:
Laurent Bartolo, Sumbul Afroz, Yi-Gen Pan, Ruozhang Xu, Lea Williams, Chin-Fang Lin, Ceylan Tanes, Kyle Bittinger, Elliot S. Friedman, Phyllis A. Gimotty, Gary D. Wu, Laura F. Su
Publikováno v:
bioRxiv
The baseline composition of T cells directly impacts later response to a pathogen, but the complexity of precursor states remains poorly defined. Here we examined the baseline state of SARS-CoV-2 specific T cells in unexposed individuals. SARS-CoV-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342fdcfe03f33b388124afaeb8e43355
https://pubmed.ncbi.nlm.nih.gov/34873598
https://pubmed.ncbi.nlm.nih.gov/34873598
Autor:
Karolina Palucka, Randy A. Albrecht, Adolfo García-Sastre, Mark M. Davis, Gerlinde Obermoser, Jacques Banchereau, Dongxia Lin, Holden T. Maecker, Priyanka B. Subrahmanyam, Virginia Pascual, Tyson H. Holmes, Laura F. Su
Publikováno v:
ImmunoHorizons
The antiviral response to influenza virus is complex and multifaceted, involving many immune cell subsets. There is an urgent need to understand the role of CD4+ T cells, which orchestrate an effective antiviral response, to improve vaccine design st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a305149912546f0b63f6c5274cb9c5
http://europepmc.org/articles/PMC7891553
http://europepmc.org/articles/PMC7891553
Identification of Human Antigen-Specific T Cells Using Class II MHC Tetramer Staining and Enrichment
Autor:
Yi-Gen Pan, Laura F. Su
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627112
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70b5451721e7ec531621d0ac4b4e2c37
https://doi.org/10.1007/978-1-0716-2712-9_3
https://doi.org/10.1007/978-1-0716-2712-9_3
Autor:
C. Garrett Rappazzo, Laurent Bartolo, Veronika I. Zarnitsyna, Phyllis A. Gimotty, Yi-Gen Pan, Patrick V. Holec, Benjamas Aiamkitsumrit, Laura F. Su, Theresa Eilola, Scott E. Hensley, Adam Marc, Criswell Lavery, Michael E. Birnbaum, Rustom Antia, Yifeng Wang
How baseline T cell characteristics impact human T cell responses to novel pathogens remains unknown. Here, we address this question by studying the CD4+ T cell response in unexposed individuals to live attenuated yellow fever virus (YFV) vaccine. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c251a1069138b7e2258cecab91b13b1
https://doi.org/10.1101/2020.10.01.322958
https://doi.org/10.1101/2020.10.01.322958
Autor:
Yifeng Wang, Adam Marc, Criswell Lavery, Veronika I. Zarnitsyna, C. Garrett Rappazzo, Patrick V. Holec, Michael E. Birnbaum, Laurent Bartolo, Yi-Gen Pan, Theresa Eilola, Rustom Antia, Laura F. Su, Benjamas Aiamkitsumrit, Scott E. Hensley, Phyllis A. Gimotty
Publikováno v:
Immunity
Summary We examined how baseline CD4+ T cell repertoire and precursor states impact responses to pathogen infection in humans using primary immunization with yellow fever virus (YFV) vaccine. YFV-specific T cells in unexposed individuals were identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f31b60767e64498e068d16fc88c135b
https://doi.org/10.1016/j.immuni.2021.04.023
https://doi.org/10.1016/j.immuni.2021.04.023
Autor:
Laura F. Su, Yi-Kan Pan, Benjamas Aiamkitsumrit, Yifeng Wang, Adam Marc, criswell Lavery, Garrett C. Rappazzo, Scott Hensley, Michael Birnbaum
Publikováno v:
The Journal of Immunology. 204:81.7-81.7
Background There is a critical unmet need for vaccines against emerging diseases and common infections, such as HIV, malaria, and tuberculosis. Defining the mechanisms by which memory T cell responses are generated in humans is essential for developi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1fe32451035cfe5f099ca3c9989a849
https://doi.org/10.4049/jimmunol.204.supp.81.7
https://doi.org/10.4049/jimmunol.204.supp.81.7