Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laura F. Mendez Luque"'
Autor:
Julio Avelar-Barragan, Laura F. Mendez Luque, Jenny Nguyen, Hellen Nguyen, Andrew O. Odegaard, Angela G. Fleischman, Katrine L. Whiteson
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTMyeloproliferative neoplasms (MPNs) are a class of rare hematological malignancies that result in the overproduction of myeloid lineage cells. These malignancies result in increased cytokine production and inflammation, which correlate with w
Externí odkaz:
https://doaj.org/article/cf10c1ce160745a5ab362ee8c7e67216
Autor:
Andrew Oliver, Kenza El Alaoui, Carolyn Haunschild, Julio Avelar-Barragan, Laura F. Mendez Luque, Katrine Whiteson, Angela G. Fleischman
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT The capacity of the human microbiome to modulate inflammation in the context of cancer is becoming increasingly clear. Myeloproliferative neoplasms (MPNs) are chronic hematologic malignancies in which inflammation plays a key role in disease
Externí odkaz:
https://doaj.org/article/deb3da710bc545f4ad4e93305f806193
Autor:
Laura F. Mendez Luque, Julio Avelar-Barragan, Hellen Nguyen, Jenny Nguyen, Eli M. Soyfer, Jiarui Liu, Jane H. Chen, Nitya Mehrotra, Heidi E. Kosiorek, Amylou Dueck, Alexander Himstead, Elena Heide, Melinda Lem, Kenza El Alaoui, Eduard Mas Marin, Robyn M. Scherber, Ruben A. Mesa, Katrine L. Whiteson, Andrew Odegaard, Angela G. Fleischman
PurposeChronic inflammation is integral to Myeloproliferative Neoplasm (MPN) pathogenesis. JAK inhibitors reduce cytokine levels, but not without significant side effects. Nutrition is a low-risk approach to reduce inflammation and ameliorate symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b586601b4267a28229505086f9b43fc
https://doi.org/10.1101/2023.05.09.23289740
https://doi.org/10.1101/2023.05.09.23289740
Autor:
Ekansh Mittal, Andrew Oliver, Kenza El Alaoui, Carolyn Haunschild, Julio Avelar-Barragan, Laura F. Mendez Luque, Katrine Whiteson, Angela G. Fleischman
Publikováno v:
Cancer Research. 83:5908-5908
Background: Cancer is the second leading cause of death in the world. Unfortunately, survival rates for cancer patients have stayed poor for many decades. Thus, there is an unmet need to identify novel strategies for early cancer detection and preven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0aba689300a55ffca21493232cfe0ff
https://doi.org/10.1158/1538-7445.am2023-5908
https://doi.org/10.1158/1538-7445.am2023-5908
Autor:
Hew Yeng Lai, Stefan Brooks, Laura F. Mendez Luque, Xinyue Chang, Brianna M. Craver, Angela G. Fleischman, Gajalakshmi Ramanathan, Summer Hoang
Publikováno v:
Blood advances, vol 4, iss 2
Thrombosis is a major cause of mortality in patients with myeloproliferative neoplasms (MPNs), though there is currently little to offer patients with MPN beyond aspirin and cytoreductive therapies such as hydroxyurea for primary prevention. Thrombog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df96a2c9862266059919856dccd4c9c0
https://doi.org/10.1182/bloodadvances.2019000967
https://doi.org/10.1182/bloodadvances.2019000967
Publikováno v:
Current hematologic malignancy reports, vol 14, iss 3
Curr Hematol Malig Rep
Curr Hematol Malig Rep
PURPOSE OF REVIEW: Chronic inflammation is a characteristic feature of myeloproliferative neoplasm (MPN) and impacts many aspects of the disease including initiation, progression, and symptomatology. RECENT FINDINGS: The chronic inflammatory state of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14ecd98b696aca36e964520195fe3d8
https://doi.org/10.1007/s11899-019-00508-w
https://doi.org/10.1007/s11899-019-00508-w
Autor:
Summer Hoang, Hew Yeng Lai, Angela G. Fleischman, Gajalakshmi Ramanathan, Laura F. Mendez Luque, Kenza Elalaoui, Stefan Brooks, Brianna M. Craver
Publikováno v:
Blood. 132:1786-1786
Chronic inflammation is common in MPN and drives disease progression and worsens symptom burden. It has been reported that JAK2V617F hematopoietic stem and progenitor cells (HSPCs) exhibit elevated basal oxidative stress compared to wild-type cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::474db552a46ac02aa86be6ac9d6e4969
https://doi.org/10.1182/blood-2018-99-117395
https://doi.org/10.1182/blood-2018-99-117395