Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Laura F. Grice"'
Autor:
Ellen R. Gillespie, Laura F. Grice, Isabel G. Courtney, Hong Wa Lao, Woncheol Jung, Sonny Ramkomuth, Jacky Xie, David A. Brown, James Walsham, Kristen J. Radford, Quan H. Nguyen, Marc J. Ruitenberg
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Next-generation humanised mouse models and single-cell RNA sequencing (scRNAseq) approaches enable in-depth studies into human immune cell biology. Here we used NSG-SGM3 mice engrafted with human umbilical cord haematopoietic stem cells to i
Externí odkaz:
https://doaj.org/article/40a7cde76523424a9dc3bc7e32ce0e7a
Autor:
Duy Pham, Xiao Tan, Brad Balderson, Jun Xu, Laura F. Grice, Sohye Yoon, Emily F. Willis, Minh Tran, Pui Yeng Lam, Arti Raghubar, Priyakshi Kalita-de Croft, Sunil Lakhani, Jana Vukovic, Marc J. Ruitenberg, Quan H. Nguyen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Spatial transcriptomics (ST) technologies generate multiple data types from biological samples, namely gene expression, physical distance between data points, and/or tissue morphology. Here we developed three computational-statistical algori
Externí odkaz:
https://doaj.org/article/90386dc9c14b4450ad2ce44635d342ec
Autor:
Arti M. Raghubar, Duy T. Pham, Xiao Tan, Laura F. Grice, Joanna Crawford, Pui Yeng Lam, Stacey B. Andersen, Sohye Yoon, Siok Min Teoh, Nicholas A. Matigian, Anne Stewart, Leo Francis, Monica S. Y. Ng, Helen G. Healy, Alexander N. Combes, Andrew J. Kassianos, Quan Nguyen, Andrew J. Mallett
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Available transcriptomes of the mammalian kidney provide limited information on the spatial interplay between different functional nephron structures due to the required dissociation of tissue with traditional transcriptome-based methodologies. A dee
Externí odkaz:
https://doaj.org/article/f9f48ceb22244753811383cd23084a84
Autor:
Timothy J. Wells, Ya Wang, Jon Iredell, Amy Phu, Sally Teoh, Win Sen Kuan, Yanshan Zhu, Melissa J. Davis, Timothy McCulloch, Majid Ebrahimi Warkiani, Tiana M Pelaia, Yao Xia, Chin Wee Tan, Timothy Kwan, Lucia de Noronha, Velma Herwanto, Reza Alizadeh-Navaei, Amir Shamshirian, Carmen Lúcia Kuniyoshi Rebelatto, John F. Fraser, Tracy Chew, Reza Valadan, Liliana Lamperti, Kenneth J. O'Byrne, Marek Nalos, Gabrielle T. Belz, Yvette Jee, Quan Nguyen, Keng Yih Chew, Maryam Shojaei, Anthony S. McLean, Benjamin Tang, Alexandra Cristina Senegaglia, Carlos Salomon Gallo, Laura F. Grice, Ben Knippenberg, Arutha Kulasinghe, Kirsty R. Short, Felipe Zuñiga, Omolbanin Amjadi, Sepideh Motamen, Estefania Nova-Lamperti, Rajan Gogna, Anna Flavia Ribeiro dos Santos, Minh Tran, Karan Kim, Fernando Souza-Fonseca-Guimaraes, James Monkman, Gustavo Rodrigues Rossi, Gonzalo Labarca, Esha Madan, Claudio Luciano Franck
BackgroundRobust biomarkers that predict disease outcomes amongst COVID-19 patients are necessary for both patient triage and resource prioritisation. Numerous candidate biomarkers have been proposed for COVID-19. However, at present, there is no con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43dd230438b36df1bcefeac6c9ac27b
https://doi.org/10.1101/2021.10.29.21265555
https://doi.org/10.1101/2021.10.29.21265555
Autor:
Laura F. Grice, Bernard M. Degnan
Publikováno v:
Marine Drugs, Vol 15, Iss 5, p 136 (2017)
Sponges, despite their simple body plan, discriminate between self and nonself with remarkable specificity. Sponge grafting experiments simulate the effects of natural self or nonself contact under laboratory conditions. Here we take a transcriptomic
Externí odkaz:
https://doaj.org/article/144e6f3a3e7b4b0d86e877829b5d4c15
Autor:
Duy Pham, Pui Yeng Lam, Siok Min Teoh, Stacey B. Andersen, Alexander N. Combes, Anne Stewart, Helen Healy, Andrew Mallett, Laura F. Grice, Quan Nguyen, Andrew J. Kassianos, L. Francis, Joanna Crawford, Sohye Yoon, Monica S.Y. Ng, Arti Raghubar, Samuel Holland, Xiao Tan
Understanding the molecular mechanisms underlying mammalian kidney function requires transcriptome profiling of the interplay between cells comprising nephron segments. Traditional transcriptomics requires cell dissociation, resulting in loss of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f9a3034f94be4bbc30dd1b5724fe95d
https://doi.org/10.1101/2020.09.29.317917
https://doi.org/10.1101/2020.09.29.317917
Autor:
Arti Raghubar, Xiao Tan, Jun Xu, Jana Vukovic, Marc J. Ruitenberg, Quan Nguyen, Laura F. Grice, Duy Pham, Pui Yeng Lam
Spatial Transcriptomics is an emerging technology that adds spatial dimensionality and tissue morphology to the genome-wide transcriptional profile of cells in an undissociated tissue. Integrating these three types of data creates a vast potential fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c908ec3abbe1e3a410e727fd760808d
https://doi.org/10.1101/2020.05.31.125658
https://doi.org/10.1101/2020.05.31.125658
Autor:
Xavier Fernàndez-Busquets, Kathrein E. Roper, Laura F. Grice, Sandie M. Degnan, Bernard M. Degnan, Marie Gauthier
Publikováno v:
Molecular Biology and Evolution
Although discriminating self from nonself is a cardinal animal trait, metazoan allorecognition genes do not appear to be homologous. Here, we characterize the Aggregation Factor (AF) gene family, which encodes putative allorecognition factors in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfd730f524e7661fa75027ed1b1db8d
http://europepmc.org/articles/PMC5400394
http://europepmc.org/articles/PMC5400394
Autor:
Bernard M. Degnan, Laura F. Grice
Publikováno v:
Marine Drugs; Volume 15; Issue 5; Pages: 136
Marine Drugs, Vol 15, Iss 5, p 136 (2017)
Marine Drugs
Marine Drugs, Vol 15, Iss 5, p 136 (2017)
Marine Drugs
Sponges, despite their simple body plan, discriminate between self and nonself with remarkable specificity. Sponge grafting experiments simulate the effects of natural self or nonself contact under laboratory conditions. Here we take a transcriptomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef56c90db2ed36cb6b2f4c2c90378386
Autor:
Laura F. Grice
The multicellular condition cannot be maintained without safeguards protecting the integrity of the individual. Tissue contact and fusion with other conspecific individuals may threaten this integrity, as genetically non-identical cells may shirk the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c974fc56870cb1e10fd9cc912efe0706
https://doi.org/10.14264/uql.2015.714
https://doi.org/10.14264/uql.2015.714