Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Laura F Gibson"'
Autor:
Allison Bruce, Rebecca Evans, Ryan Mezan, Lin Shi, Blake S Moses, Karen H Martin, Laura F Gibson, Yong Yang
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140506 (2015)
Acute lymphoblastic leukemia (ALL) initiates and progresses in the bone marrow, and as such, the marrow microenvironment is a critical regulatory component in development of this cancer. However, ALL studies were conducted mainly on flat plastic subs
Externí odkaz:
https://doaj.org/article/88a95ad7fdfe4f8dacabe847a30a18dd
Autor:
Stephanie L Rellick, Heather O'Leary, Debbie Piktel, Cheryl Walton, James E Fortney, Stephen M Akers, Karen H Martin, James Denvir, Goran Boskovic, Donald A Primerano, Jeffrey Vos, Nathanael Bailey, Marieta Gencheva, Laura F Gibson
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30758 (2012)
Hematopoietic reconstitution, following bone marrow or stem cell transplantation, requires a microenvironment niche capable of supporting both immature progenitors and stem cells with the capacity to differentiate and expand. Osteoblasts comprise one
Externí odkaz:
https://doaj.org/article/aa83f367457448d29e2aff0cf4282d0f
Autor:
Fariba Rezaee, Stephanie L Rellick, Giovanni Piedimonte, Stephen M Akers, Heather A O'Leary, Karen Martin, Michael D Craig, Laura F Gibson
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9690 (2010)
The host's response to infection is characterized by altered levels of neurotrophins and an influx of inflammatory cells to sites of injured tissue. Progenitor cells that give rise to the differentiated cellular mediators of inflammation are derived
Externí odkaz:
https://doaj.org/article/6ef6d67f21374aa7bf06f210a00ea4bf
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6444 (2009)
BACKGROUND:Overall expression of neurotrophins in the respiratory tract is upregulated in infants infected by the respiratory syncytial virus (RSV), but it is unclear where (structural vs. inflammatory cells, upper vs. lower airways) and why, these c
Externí odkaz:
https://doaj.org/article/74a8a1bdb0bd4f108321e7f9484367c3
Autor:
Laura F. Gibson, Michael D. Craig, Ivan Martinez, Debbie Piktel, William L. Slone, Rebecca Evans, Blake S. Moses
S2A, REH leukemic cells have overexpressed p27 protein compared to empty vector control. S2B, an increase in viability was observed in REH cells overexpressing p27 compared to empty vector control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039b7355d19e4a9c2371968fdea2a569
https://doi.org/10.1158/1541-7786.22514092
https://doi.org/10.1158/1541-7786.22514092
Autor:
Laura F. Gibson, Michael D. Craig, Ivan Martinez, Debbie Piktel, William L. Slone, Rebecca Evans, Blake S. Moses
Excel sheet showing mean signal intensities and p-values of SUP-B15 ALL cells cultured in media only or co-cultured with BMSC. Statistics were done as follows: Data were analyzed by first subtracting the background and then normalizing the signals us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f4c4d69be602a607f93ad03b0a5640
https://doi.org/10.1158/1541-7786.22514089
https://doi.org/10.1158/1541-7786.22514089
Autor:
Laura F. Gibson, Michael D. Craig, Ivan Martinez, Debbie Piktel, William L. Slone, Rebecca Evans, Blake S. Moses
Consistent with p27 two other validated miR-221/222 target genes which have been previously shown to play a role in cellular quiescence and survival, PTEN and CDKN1C (p57), were assessed in leukemic cells under conditions mentioned above. S1A,B, both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cdac0af735c96284c88621853e00d6
https://doi.org/10.1158/1541-7786.22514095
https://doi.org/10.1158/1541-7786.22514095
Autor:
Laura F. Gibson, Michael D. Craig, Ivan Martinez, Debbie Piktel, William L. Slone, Rebecca Evans, Blake S. Moses
Excel sheet showing mean signal intensities and p-values of SUP-B15 ALL cells cultured in media only or co-cultured with HOB. Statistics were done as follows: Data were analyzed by first subtracting the background and then normalizing the signals usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a2ae256ffa5d39dc2aa943ec98c296
https://doi.org/10.1158/1541-7786.22514086.v1
https://doi.org/10.1158/1541-7786.22514086.v1
Autor:
Debbie Piktel, Javohn C. Moore, Sloan Nesbit, Samuel A. Sprowls, Michael D. Craig, Stephanie L. Rellick, Rajesh R. Nair, Ethan Meadows, John M. Hollander, Werner J. Geldenhuys, Karen H. Martin, Laura F. Gibson
Publikováno v:
Cancers
Volume 15
Issue 3
Pages: 707
Volume 15
Issue 3
Pages: 707
B-cell acute lymphoblastic leukemia (ALL) is derived from an accumulation of malignant, immature B cells in the bone marrow and blood. Relapse due, in part, to the emergence of tumor cells that are resistant to front line standard chemotherapy is ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0ecc62a089e43b41acd8a62869cb2e
Autor:
Ian Hare, Marieta Gencheva, Rebecca Evans, James Fortney, Debbie Piktel, Jeffrey A. Vos, David Howell, Laura F. Gibson
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Mesenchymal stem cells (MSCs) are of interest for use in diverse cellular therapies. Ex vivo expansion of MSCs intended for transplantation must result in generation of cells that maintain fidelity of critical functions. Previous investigations have
Externí odkaz:
https://doaj.org/article/40b3bbe43505473f9c4c66c31c75254a