Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Laura E. Savolainen"'
Autor:
Laura E. Savolainen, Susanne Kilpinen, M. Speeti, H. Pekkarinen, Niina Airas, Antti Sukura, Pernilla Syrjä, O. Miuku, Veera Karkamo, Martti Vaara, Merja Rantala, Sanna Malkamäki
Publikováno v:
Journal of Comparative Pathology
Mycobacteriosis caused by non-tuberculous mycobacteria (NTM) is a rising concern in human medicine both in immunocompromised and immunocompetent patients. In cats, mycobacteriosis caused by NTM is considered mostly to be a focal or dermal infection,
Identification of urinary tract pathogens after 3-hours urine culture by MALDI-TOF mass spectrometry
Publikováno v:
Journal of Microbiological Methods. 129:81-84
Complicated urinary tract infections, such as pyelonephritis, may lead to sepsis. Rapid diagnosis is needed to identify the causative urinary pathogen and to verify the appropriate empirical antimicrobial therapy. We describe here a rapid identificat
Publikováno v:
Journal of Separation Science. 39:2853-2861
Tuberculosis is a devastating contagious disease caused by Mycobacterium tuberculosis. This is the first report describing the development of novel capillary electrophoresis methods to detect lipoarabinomannans shed into the blood circulation by repl
Autor:
Riitta Karttunen, Laura E. Savolainen, Heikki Valleala, Anu Kantele, Aija Knuuttila, Tamara Tuuminen, Liana Pusa
Publikováno v:
Frontiers in Immunology
New biomarkers are needed for discriminating active tuberculosis (TB) from latent TB infection (LTBI), especially in vulnerable groups representing the major diagnostic challenge. This pilot study was carried out to explore the diagnostic potential o
Publikováno v:
Journal of separation science. 39(14)
Tuberculosis is a devastating contagious disease caused by Mycobacterium tuberculosis. This is the first report describing the development of novel capillary electrophoresis methods to detect lipoarabinomannans shed into the blood circulation by repl
Autor:
Eveliina Tarkka, Heli Piiparinen, Minna Mäki, Sanna Laakso, C Carder, Laura E. Savolainen, Päivi Tissari, Sointu Mero, Alimuddin Zumla, Martti Vaara, Anne Aittakorpi, Vanya Gant, Merja Lindfors, Jim F. Huggett
Publikováno v:
The Lancet. 375:224-230
Summary Background New DNA-based microarray platforms enable rapid detection and species identification of many pathogens, including bacteria. We assessed the sensitivity, specificity, and turnaround time of a new molecular sepsis assay. Methods 2107
Publikováno v:
Vaccine. 33(3)
BackgroundSince protective efficacy of the current typhoid vaccines—oral whole-cell Salmonella Typhi Ty21a and parenteral Vi-capsular polysaccharide preparation—is not optimal, and no vaccines are available against paratyphoid or non-typhoidal Sa
Autor:
Riitta Erkinjuntti-Pekkanen, Cheng-Lung Ku, Laura E. Savolainen, Anu Kantele, Aija Knuuttila, Bettina Sandboge, Tamara Tuuminen, Riitta Tuompo, Liana Pusa, Chih-Yu Chi, Marita Sirén, Tuula Vasankari, Heikki Valleala
Publikováno v:
Clinical and vaccine immunology : CVI. 20(9)
Diagnosis of active tuberculosis by detection of urinary lipoarabinomannan (uLAM) from Mycobacterium tuberculosis is an attractive approach. Concentrating urine 100-fold allowed quantitation of uLAM at levels equal to picograms/ml of nonconcentrated
Autor:
Pernilla Syrjä, Veera Karkamo, Laura E. Savolainen, S. Sukura, M. Speeti, H. Bäckman, Martti Vaara
Publikováno v:
Journal of Comparative Pathology. 154:120
Autor:
Tamara Tuuminen, Heidi Sillanpää, Liana Pusa, Hwa-Jung Kim, Laura E. Savolainen, Ilkka Seppälä
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 9, p e3272 (2008)
PLoS ONE, Vol 3, Iss 9, p e3272 (2008)
BACKGROUND: In recent years T cell based interferon gamma release assays (IGRA) have been developed for immunodiagnosis of M. tuberculosis infection. At present these assays do not discriminate between disease and latency. Therefore, more promising a