Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura E. Marshall"'
Autor:
Laura E. Marshall, Michelle Nelson, Carwyn H. Davies, Adam O. Whelan, Dominic C. Jenner, Madeleine G. Moule, Carmen Denman, Jon Cuccui, Timothy P. Atkins, Brendan W. Wren, Joann L. Prior
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
There is a requirement for an efficacious vaccine to protect people against infection from Francisella tularensis, the etiological agent of tularemia. The lipopolysaccharide (LPS) of F. tularensis is suboptimally protective against a parenteral letha
Externí odkaz:
https://doaj.org/article/2bc623d9492c4a739837f0fe3d976a9a
Autor:
Jua Iwasaki, Donald D. Lorimer, Mirella Vivoli-Vega, Emily A. Kibble, Christopher S. Peacock, Jan Abendroth, Stephen J. Mayclin, David M. Dranow, Phillip G. Pierce, David Fox, Maria Lewis, Nicole M. Bzdyl, Sofie S. Kristensen, Timothy J. J. Inglis, Charlene M. Kahler, Charles S. Bond, Anja Hasenkopf, Florian Seufert, Jens Schmitz, Laura E. Marshall, Andrew E. Scott, Isobel H. Norville, Peter J. Myler, Ulrike Holzgrabe, Nicholas J. Harmer, Mitali Sarkar-Tyson
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1625-1634
Background The macrophage infectivity potentiator (Mip) protein, which belongs to the immunophilin superfamily, is a peptidyl-prolyl cis/trans isomerase (PPIase) enzyme. Mip has been shown to be important for virulence in a wide range of pathogenic m
Autor:
Dominic C. Jenner, Jon Cuccui, Michelle Nelson, Adam O. Whelan, Laura E. Marshall, Joann L. Prior, Madeleine G. Moule, Brendan W. Wren, Carwyn Davies, Timothy P. Atkins, Carmen C. Denman
Publikováno v:
Marshall, L E, Nelson, M, Davies, C H, Whelan, A O, Jenner, D C, Moule, M G, Denman, C, Cuccui, J, Atkins, T P, Wren, B W & Prior, J L 2018, ' An O-Antigen glycoconjugate vaccine produced using protein glycan coupling technology is protective in an inhalational rat model of tularemia ', Journal of Immunology Research, vol. 2018, 8087916 . https://doi.org/10.1155/2018/8087916
Journal of Immunology Research, Vol 2018 (2018)
Journal of Immunology Research
Journal of Immunology Research, Vol 2018 (2018)
Journal of Immunology Research
There is a requirement for an efficacious vaccine to protect people against infection fromFrancisella tularensis, the etiological agent of tularemia. The lipopolysaccharide (LPS) ofF. tularensisis suboptimally protective against a parenteral lethal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe3edeafb4a024b60af3802fd3e93d0
https://www.pure.ed.ac.uk/ws/files/161939217/8087916.pdf
https://www.pure.ed.ac.uk/ws/files/161939217/8087916.pdf
Publikováno v:
Microbial Pathogenesis. :55-58
Burkholderia pseudomallei is a Gram negative soil saprophyte that causes the disease melioidosis where clinical symptoms can vary from localised infection to pneumonia and septic shock. Ecotin is a potent periplasmic serine protease inhibitor first i
Autor:
Paul Rösch, Michael Hein, Isobel H. Norville, Kristian Schweimer, Ulrike Holzgrabe, Mitali Sarkar-Tyson, Heike Bruhn, Christoph A. Sotriffer, Matthias Weiwad, Florian Seufert, Mirella Vivoli, Maximilian Kuhn, Laura E. Marshall, Nicholas J. Harmer
Publikováno v:
Bioorganicmedicinal chemistry. 24(21)
The bacteria Burkholderia pseudomallei and Legionella pneumophila cause severe diseases like melioidosis and Legionnaire's disease with high mortality rates despite antibiotic treatment. Due to increasing antibiotic resistances against these and othe
Autor:
Laura E. Marshall, Stephanie Tay, Jennifer L. Martin, Maria A. Halili, Róisín M. McMahon, Emily Furlong, Philip M. Ireland, Mitali Sarkar-Tyson
Aims: The intracellular pathogen Burkholderia pseudomallei causes the disease melioidosis, a major source of morbidity and mortality in southeast Asia and northern Australia. The need to develop novel antimicrobials is compounded by the absence of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36b28c8fe0d3bbd2be8e77e397e10f0
https://europepmc.org/articles/PMC3901323/
https://europepmc.org/articles/PMC3901323/
Publikováno v:
Journal of the American Chemical Society. 102:5419-5421
Publikováno v:
Journal of the American Chemical Society. 103:3582-3584
Publikováno v:
Biochemistry. 20(2)
Autor:
Richard H. Himes, Laura E. Marshall
Publikováno v:
Biochimica et biophysica acta. 543(4)
Rotenone effectively inhibits the in vitro formation of microtubules from tubulin containing or lacking microtubules-associated proteins. In both cases a concentration of rotenone equal to that of tubulin present completely blocks assembly. The inhib