Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Laura E. Maida"'
Autor:
Colette T. Dooley, Richard A. Houghten, Margaret E. Cazares, Jiaan Shao, Miao Hu, Austin B. Yongye, Radleigh G. Santos, Elisa Mizrachi, Jay P. McLaughlin, Marc A. Giulianotti, Ginamarie Debevec, Michelle L. Ganno, Shainnel O. Eans, Jaime A. Misler, Ling Li, Laura E. Maida, Phaedra Geer, Yongping Yu
Publikováno v:
European Journal of Medicinal Chemistry. 92:270-281
A novel series of endomorphin-1 (EM-1) and endomorphin-2 (EM-2) analogues was synthesized, incorporating chiral α-hydroxy-β-phenylalanine (AHPBA), and/or Dmt(1)-Tic(2) at different positions. Pharmacological activity and metabolic stability of the
Autor:
Yaohong Zhang, Laura E. Maida, Marc A. Giulianotti, Yongping Yu, Jinhua Wu, Richard A. Houghten, Gregory S. Welmaker, Adel Nefzi, Travis LaVoi, Radleigh G. Santos, Lawrence Toll
Publikováno v:
Journal of Medicinal Chemistry. 56:10103-10117
Nicotine binds to nicotinic acetylcholine receptors (nAChR), which can exist as many different subtypes. The α4β2 nAChR is the most prevalent subtype in the brain and possesses the most evidence linking it to nicotine seeking behavior. Herein we re
Autor:
Ginamarie Debevec, Margaret E. Cazares, Laura E. Maida, Jaime A. Misler, Yangmei Li, Richard A. Houghten, Colette T. Dooley, Marc A. Giulianotti
Publikováno v:
ACS Combinatorial Science. 14:673-679
A positional scanning cyclic peptide library was generated using a penta-peptide thioester scaffold. Glycine was fixed at position R(1). Diaminopropionic acid was fixed at position R(3), with its γ-amino attaching to an anthraniloyl group. Positions
Autor:
Marc Giulianotti, Laura E. Maida, Richard A. Houghten, Mare Cudic, Nina Bionda, Gregg B. Fields, Dmitriy Minond
Publikováno v:
Peptides Across the Pacific: The Proceedings of the Twenty-Third American and the Sixth International Peptide Symposium.
Autor:
Laura E. Maida, Gregg B. Fields, Marc A. Giulianotti, Mare Cudic, Nina Bionda, Dmitriy Minond, Richard A. Houghten
Publikováno v:
The Journal of biological chemistry. 287(43)
A disintegrin and metalloprotease (ADAM) proteases are implicated in multiple diseases, but no drugs based on ADAM inhibition exist. Most of the ADAM inhibitors developed to date feature zinc-binding moieties that target the active site zinc, which l
Autor:
Radleigh G. Santos, Marc A. Giulianotti, Laura E. Maida, Colette T. Dooley, Yongping Yu, Lili Ou, Richard A. Houghten, Wenteng Chen, Ginamarie Debevec
A novel method for the direct evaluation of the equimolarity of the compounds contained in a mixture is presented. We applied the method toward calculating isokinetic ratios for the reaction between the amine termini of a resin bound peptide fragment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc89b32eea31ec01fb86d9b5d0e1cbdc
https://europepmc.org/articles/PMC3825827/
https://europepmc.org/articles/PMC3825827/