Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Laura E. Gibbons"'
Autor:
Moonil Kang, Ting Fang Alvin Ang, Sherral A. Devine, Richard Sherva, Shubhabrata Mukherjee, Emily H. Trittschuh, Laura E. Gibbons, Phoebe Scollard, Michael Lee, Seo-Eun Choi, Brandon Klinedinst, Connie Nakano, Logan C. Dumitrescu, Alaina Durant, Timothy J. Hohman, Michael L. Cuccaro, Andrew J. Saykin, Walter A. Kukull, David A. Bennett, Li-San Wang, Richard P. Mayeux, Jonathan L. Haines, Margaret A. Pericak-Vance, Gerard D. Schellenberg, Paul K. Crane, Rhoda Au, Kathryn L. Lunetta, Jesse B. Mez, Lindsay A. Farrer
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background More than 75 common variant loci account for only a portion of the heritability for Alzheimer’s disease (AD). A more complete understanding of the genetic basis of AD can be deduced by exploring associations with AD-related endo
Externí odkaz:
https://doaj.org/article/fe39bfd5b90d4d70a686b48ed5244454
Autor:
Jason M. Webster, Thomas J. Grabowski, Tara M. Madhyastha, Laura E. Gibbons, C. Dirk Keene, Caitlin S. Latimer
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
IntroductionThe study of Alzheimer’s disease investigates topographic patterns of degeneration in the context of connected networks comprised of functionally distinct domains using increasingly sophisticated molecular techniques. Therefore, obtaini
Externí odkaz:
https://doaj.org/article/43d99c091745404ab6a2c2f159e95d65
Autor:
Nadia Postupna, Shannon E. Rose, Laura E. Gibbons, Natalie M. Coleman, Leanne L. Hellstern, Kayla Ritchie, Angela M. Wilson, Eiron Cudaback, Xianwu Li, Erica J. Melief, Allison E. Beller, Jeremy A. Miller, Amber L. Nolan, Desiree A. Marshall, Rod Walker, Thomas J. Montine, Eric B. Larson, Paul K. Crane, Richard G. Ellenbogen, Edward S. Lein, Kristen Dams-O'Connor, C. Dirk Keene
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
The late neuropathological effects of traumatic brain injury have yet to be fully elucidated, particularly with respect to community-based cohorts. To contribute to this critical gap in knowledge, we designed a multimodal neuropathological study, int
Externí odkaz:
https://doaj.org/article/9d4ce0378ae94ea494bf39044a1146f3
Autor:
Caitlin S. Latimer, Bridget T. Burke, Nicole F. Liachko, Heather N. Currey, Mitchell D. Kilgore, Laura E. Gibbons, Jonathan Henriksen, Martin Darvas, Kimiko Domoto-Reilly, Suman Jayadev, Tom J. Grabowski, Paul K. Crane, Eric B. Larson, Brian C. Kraemer, Thomas D. Bird, C. Dirk Keene
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-24 (2019)
Abstract Alzheimer’s disease neuropathologic change (ADNC) is defined by progressive accumulation of β-amyloid plaques and hyperphosphorylated tau (pTau) neurofibrillary tangles across diverse regions of brain. Non-demented individuals who reach a
Externí odkaz:
https://doaj.org/article/bc0a491ce3824f00984ecbed34fa9ee7
Autor:
Madeline Uretsky, Laura E. Gibbons, Shubhabrata Mukherjee, Emily H. Trittschuh, David W. Fardo, Patricia A. Boyle, C. Dirk Keene, Andrew J. Saykin, Paul K. Crane, Julie A. Schneider, Jesse Mez
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 7, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Alzheimer's disease (AD) neuropathological subtypes (limbic predominant [lpAD], hippocampal sparing [HpSpAD], and typical [tAD]), defined by relative neurofibrillary tangle (NFT) burden in limbic and cortical regions, have not b
Externí odkaz:
https://doaj.org/article/ff4e466cadfb4da390e2a876101beff0
Autor:
Seo‐Eun Choi, Shubhabrata Mukherjee, Laura E. Gibbons, R. Elizabeth Sanders, Richard N. Jones, Douglas Tommet, Jesse Mez, Emily H. Trittschuh, Andrew Saykin, Melissa Lamar, Laura Rabin, Nancy S. Foldi, Sietske Sikkes, Roos J. Jutten, Evan Grandoit, Christine Mac Donald, Shannon Risacher, Colin Groot, Rik Ossenkoppele, for the Alzheimer's Disease Neuroimaging Initiative, Paul K. Crane
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Composite scores may be useful to summarize overall language or visuospatial functioning in studies of older adults. Methods We used item response theory to derive composite measures for language (ADNI‐Lan) and visuospatial fu
Externí odkaz:
https://doaj.org/article/391b3e583d5d483083711329efa0e4be
Autor:
Jesse Mez, Jessica R. Marden, Shubhabrata Mukherjee, Stefan Walter, Laura E. Gibbons, Alden L. Gross, Laura B. Zahodne, Paola Gilsanz, Paul Brewster, Kwangsik Nho, Paul K. Crane, Eric B. Larson, M. Maria Glymour
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 8, Iss 1, Pp 188-195 (2017)
Abstract Introduction We hypothesized that, like apolipoprotein E (APOE), other late‐onset Alzheimer's disease (LOAD) genetic susceptibility loci predict mortality. Methods We used a weighted genetic risk score (GRS) from 21 non‐APOE LOAD risk va
Externí odkaz:
https://doaj.org/article/cfd6bf6ee47a4dd1916b47d0a4398157
Autor:
Meghan B. Mitchell, Cynthia R. Cimino, Andreana Benitez, Cassandra L. Brown, Laura E. Gibbons, Robert F. Kennison, Steven D. Shirk, Alireza Atri, Annie Robitaille, Stuart W. S. MacDonald, Magnus Lindwall, Elizabeth M. Zelinski, Sherry L. Willis, K. Warner Schaie, Boo Johansson, Roger A. Dixon, Dan M. Mungas, Scott M. Hofer, Andrea M. Piccinin
Publikováno v:
Journal of Aging Research, Vol 2012 (2012)
Engagement in cognitively stimulating activities has been considered to maintain or strengthen cognitive skills, thereby minimizing age-related cognitive decline. While the idea that there may be a modifiable behavior that could lower risk for cognit
Externí odkaz:
https://doaj.org/article/3240cea427ba4158ad21970d5ab2e292
Autor:
Magnus Lindwall, Cynthia R. Cimino, Laura E. Gibbons, Meghan B. Mitchell, Andreana Benitez, Cassandra L. Brown, Robert F. Kennison, Steven D. Shirk, Alireza Atri, Annie Robitaille, Stuart W. S. MacDonald, Elizabeth M. Zelinski, Sherry L. Willis, K. Warner Schaie, Boo Johansson, Marcus Praetorius, Roger A. Dixon, Dan M. Mungas, Scott M. Hofer, Andrea M. Piccinin
Publikováno v:
Journal of Aging Research, Vol 2012 (2012)
The present study used a coordinated analyses approach to examine the association of physical activity and cognitive change in four longitudinal studies. A series of multilevel growth models with physical activity included both as a fixed (between-pe
Externí odkaz:
https://doaj.org/article/a3fddc3fa0914e16b1c51a9d1d370528
Autor:
Cassandra L. Brown, Laura E. Gibbons, Robert F. Kennison, Annie Robitaille, Magnus Lindwall, Meghan B. Mitchell, Steven D. Shirk, Alireza Atri, Cynthia R. Cimino, Andreana Benitez, Stuart W. S. MacDonald, Elizabeth M. Zelinski, Sherry L. Willis, K. Warner Schaie, Boo Johansson, Roger A. Dixon, Dan M. Mungas, Scott M. Hofer, Andrea M. Piccinin
Publikováno v:
Journal of Aging Research, Vol 2012 (2012)
Social activity is typically viewed as part of an engaged lifestyle that may help mitigate the deleterious effects of advanced age on cognitive function. As such, social activity has been examined in relation to cognitive abilities later in life. How
Externí odkaz:
https://doaj.org/article/6320c43f31ff49809564bd9343e2073e