Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Laura E. Ewing"'
Autor:
Kristy R. Kutanzi, Laura E. Ewing, Charles M. Skinner, Charles M. Quick, Stefanie Kennon-McGill, Mitchell R. McGill, Larry A. Walker, Mahmoud A. ElSohly, Bill J. Gurley, Igor Koturbash
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7808 (2020)
Cannabidiol (CBD) is a biologically active, non-psychotropic component of Cannabis sativa whose popularity has grown exponentially in recent years. Besides a wealth of potential health benefits, ingestion of CBD poses risks for a number of side effec
Externí odkaz:
https://doaj.org/article/6a4973519076452e92fb2a6cd995a71f
Autor:
Laura E. Ewing, Mitchell R. McGill, Eric U. Yee, Charles M. Quick, Charles M. Skinner, Stefanie Kennon-McGill, Melissa Clemens, Joel H. Vazquez, Sandra S. McCullough, D. Keith Williams, Kristy R. Kutanzi, Larry A. Walker, Mahmoud A. ElSohly, Laura P. James, Bill J. Gurley, Igor Koturbash
Publikováno v:
Molecules, Vol 24, Iss 12, p 2256 (2019)
The goal of this study was to investigate the potential for a cannabidiol-rich cannabis extract (CRCE) to interact with the most common over-the-counter drug and the major known cause of drug-induced liver injury−acetaminophen (APAP)−in aged fema
Externí odkaz:
https://doaj.org/article/7632106643014667a583ed2b9a4fefcb
Autor:
Bill J. Gurley, Isabelle R. Miousse, Intawat Nookaew, Laura E. Ewing, Charles M. Skinner, Piroon Jenjaroenpun, Thidathip Wongsurawat, Stefanie Kennon-McGill, Bharathi Avula, Ji-Yeong Bae, Mitchell R. McGill, David Ussery, Ikhlas A. Khan, Igor Koturbash
Publikováno v:
Nutrients, Vol 11, Iss 4, p 776 (2019)
The main purpose of this study was to investigate the hepatotoxic potential and effects on the gut microbiome of decaffeinated green tea extract (dGTE) in lean B6C3F1 mice. Gavaging dGTE over a range of 1X–10X mouse equivalent doses (MED) for up to
Externí odkaz:
https://doaj.org/article/9cc855e3e5294198a45f16958e002ca5
Autor:
Laura E. Ewing, Charles M. Skinner, Charles M. Quick, Stefanie Kennon-McGill, Mitchell R. McGill, Larry A. Walker, Mahmoud A. ElSohly, Bill J. Gurley, Igor Koturbash
Publikováno v:
Molecules, Vol 24, Iss 9, p 1694 (2019)
The goal of this study was to investigate Cannabidiol (CBD) hepatotoxicity in 8-week-old male B6C3F1 mice. Animals were gavaged with either 0, 246, 738, or 2460 mg/kg of CBD (acute toxicity, 24 h) or with daily doses of 0, 61.5, 184.5, or 615 mg/kg f
Externí odkaz:
https://doaj.org/article/838b653cc80b41178d9118a2e4125367
Autor:
Ashley S. Nemec-Bakk, Vijayalakshmi Sridharan, John W. Seawright, Gregory A. Nelson, Maohua Cao, Preeti Singh, Amrita K. Cheema, Bhaldev Singh, Yaoxiang Li, Igor Koturbash, Isabelle R. Miousse, Laura E. Ewing, Charles M. Skinner, Reid D. Landes, John D. Lowery, Xiao-Wen Mao, Sharda P. Singh, Marjan Boerma
Publikováno v:
Life Sciences in Space Research. 37:78-87
Autor:
Laura E. Ewing, Rupak Pathak, Reid D. Landes, Charles M. Skinner, Regina Binz, Sean G. Young, Sheldon Riklon, Shelbie Stahr, Joseph Su, Marjan Boerma, Pearl A. McElfish, Martin Hauer-Jensen, Igor Koturbash
Publikováno v:
International Journal of Radiation Biology. 99:644-655
Nuclear weapons testing in the northern Marshall Islands between 1946 and 1958 resulted in ionizing radiation (IR) exposure of the thousands of Marshallese. Furthermore, numerous islands were contaminated by radioactive fallout. Significant increases
Methods for induction and assessment of intestinal permeability in rodent models of radiation injury
Autor:
Laura E. Ewing, Prabath G. Biju, Rupak Pathak, Stepan Melnyk, Martin Hauer-Jensen, Igor Koturbash
Publikováno v:
Methods Cell Biol
Methods in Cell Biology ISBN: 9780323899451
Methods in Cell Biology ISBN: 9780323899451
Ionizing radiation (IR) is a significant contributor to the contemporary market of energy production and an important diagnostic and treatment modality. Besides having numerous useful applications, it is also a ubiquitous environmental stressor and a
Autor:
Charles E Hay, Guillermo A Gonzalez, Laura E Ewing, E Elizabeth Reichard, Michael D Hambuchen, Nisha Nanaware-Kharade, Sinthia Alam, Chris T Bolden, S Michael Owens, Paris Margaritis, Eric C Peterson
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0200060 (2018)
Methamphetamine (METH) substance abuse disorders have major impact on society, yet no medications have proven successful at preventing METH relapse or cravings. Anti-METH monoclonal antibodies can reduce METH brain concentrations; however, this thera
Externí odkaz:
https://doaj.org/article/a3b7cda581564b6da93d3379f3633e3c
Autor:
Martin Hauer-Jensen, Sarita Garg, Isabelle R. Miousse, Charles M. Skinner, Stepan Melnyk, Rupak Pathak, Laura E. Ewing, Igor Koturbash, Kristy Kutanzi
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Methionine is an essential amino acid needed for a variety of processes in living organisms. Ionizing radiation depletes tissue methionine concentrations and leads to the loss of DNA methylation and decreased synthesis of glutathione. In this study,
Autor:
Martin Hauer-Jensen, Igor Koturbash, Laura E. Ewing, Marjan Boerma, Charles M. Skinner, Rupak Pathak, Stanley D. Kosanke, Isabelle R. Miousse
Publikováno v:
Int J Radiat Biol
PURPOSE. Growing rates of metabolic syndrome and associated obesity warrant the development of appropriate animal models for better understanding of how those conditions may affect sensitivity to IR exposure. MATERIALS AND METHODS. We subjected male