Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Laura E. Crotty Alexander"'
Autor:
Nisha Tapryal, Anirban Chakraborty, Kaushik Saha, Azharul Islam, Lang Pan, Koa Hosoki, Ibrahim M. Sayed, Jason M. Duran, Joshua Alcantara, Vanessa Castillo, Courtney Tindle, Altaf H. Sarker, Maki Wakamiya, Victor J. Cardenas, Gulshan Sharma, Laura E. Crotty Alexander, Sanjiv Sur, Debashis Sahoo, Gourisankar Ghosh, Soumita Das, Pradipta Ghosh, Istvan Boldogh, Tapas K. Hazra
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract SARS-CoV-2 infection-induced aggravation of host innate immune response not only causes tissue damage and multiorgan failure in COVID-19 patients but also induces host genome damage and activates DNA damage response pathways. To test whether
Externí odkaz:
https://doaj.org/article/a49dab695e8a47c59e6fe11737dc9248
Transcriptomic responses in the blood and sputum of cigarette smokers compared to e-cigarette vapers
Autor:
Mario F. Perez, Marina Yurieva, Spandana Poddutoori, Eric M. Mortensen, Laura E. Crotty Alexander, Adam Williams
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Rationale Electronic (e)-cigarettes are popular among youth and cigarette smokers attempting to quit. Studies to date have focused on the utility of e-cigarettes as a smoking cessation tool, but the biological effects are largely unknown. Ob
Externí odkaz:
https://doaj.org/article/a5b311460bd240d2a7bd9d5ef7fed504
Autor:
Ira Advani, Deepti Gunge, Shreyes Boddu, Sagar Mehta, Kenneth Park, Samantha Perera, Josephine Pham, Sedtavut Nilaad, Jarod Olay, Lauren Ma, Jorge Masso-Silva, Xiaoying Sun, Sonia Jain, Atul Malhotra, Laura E. Crotty Alexander
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The health effects of e-cigarettes remain relatively unknown, including their impact on sleep quality. We previously showed in a pilot study that females who smoke both conventional tobacco and vape e-cigarettes (dual users) had decreased sl
Externí odkaz:
https://doaj.org/article/eb91a1951bcd46db92af583484871689
Autor:
Jorge Adrian Masso-Silva, George Sakoulas, Jarod Olay, Victoria Groysberg, Matthew Geriak, Victor Nizet, Laura E. Crotty Alexander, Angela Meier
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pathogenesis of lung injury in COVID-19 is not completely understood, leaving gaps in understanding how current treatments modulate the course of COVID-19. Neutrophil numbers and activation state in circulation have been found to correlate with COVID
Externí odkaz:
https://doaj.org/article/cda94e8d70514b4d8c0ccb7955474984
Autor:
Alexander Moshensky, Mulong Du, John Shin, Ira Advani, Deepti Gunge, Denzil Mathew, Rita Alkolla, Ashley Du, Christian Javier, Lauren Ma, Albert Tran, Nicholas Nguyen, Jarod Olay, Sedtavut Nilaad, Jeffrey Ding, Mahan Najhawan, Jeramie D. Watrous, Christine M. Bojanowksi, Mohit Jain, David C. Christiani, Laura E. Crotty Alexander
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Externí odkaz:
https://doaj.org/article/2f67de7dab9048229df88b3bf5e6b175
Autor:
Debashis Sahoo, Gajanan D. Katkar, Soni Khandelwal, Mahdi Behroozikhah, Amanraj Claire, Vanessa Castillo, Courtney Tindle, MacKenzie Fuller, Sahar Taheri, Thomas F. Rogers, Nathan Beutler, Sydney I. Ramirez, Stephen A. Rawlings, Victor Pretorius, Davey M. Smith, Dennis R. Burton, Laura E. Crotty Alexander, Jason Duran, Shane Crotty, Jennifer M. Dan, Soumita Das, Pradipta Ghosh
Publikováno v:
EBioMedicine, Vol 68, Iss , Pp 103390- (2021)
Background: Coronavirus Disease 2019 (Covid-19) continues to challenge the limits of our knowledge and our healthcare system. Here we sought to define the host immune response, a.k.a, the “cytokine storm” that has been implicated in fatal COVID-1
Externí odkaz:
https://doaj.org/article/9fb0f37039614a41b6bb64dc3f67cb9a
Autor:
Jorge A. Masso-Silva, Alexander Moshensky, John Shin, Jarod Olay, Sedtavut Nilaad, Ira Advani, Christine M. Bojanowski, Shane Crotty, Wei Tse Li, Weg M. Ongkeko, Sunit Singla, Laura E. Crotty Alexander
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Conventional smoking is known to both increase susceptibility to infection and drive inflammation within the lungs. Recently, smokers have been found to be at higher risk of developing severe forms of coronavirus disease 2019 (COVID-19). E-cigarette
Externí odkaz:
https://doaj.org/article/3fe25d585d13414d9edfe01b35d3b6d0
Autor:
Jessica Chopyk, Christine M. Bojanowski, John Shin, Alex Moshensky, Ana Lucia Fuentes, Saniya S. Bonde, Dagni Chuki, David T. Pride, Laura E. Crotty Alexander
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Electronic (e)-cigarettes have been advocated as a safer alternative to conventional tobacco cigarettes. However, there is a paucity of data regarding the impact of e-cigarette aerosol deposition on the human oral microbiome, a key component in human
Externí odkaz:
https://doaj.org/article/e575ebde5abb474b83e2ef91a78b2cce
Publikováno v:
Saudi Pharmaceutical Journal, Vol 26, Iss 5, Pp 622-628 (2018)
Pre-clinical studies investigated the effects of chronic exposure to nicotine on lungs, kidneys and brains using animal models. Most of these studies delivered nicotine into the circulatory and central nervous systems (CNS) through intraperitoneal in
Externí odkaz:
https://doaj.org/article/c20ae8042d1d4e188578a297cfdfe863
Autor:
Fawaz Alasmari, Laura E. Crotty Alexander, Alaa M. Hammad, Christine M. Bojanowski, Alex Moshensky, Youssef Sari
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Electronic (E)-cigarettes are the latest form of nicotine delivery device and are highly popular in the general population. It is currently unknown whether vaping E-cigarettes (E-CIGs) leads to nicotine addiction. Alterations in the levels of the neu
Externí odkaz:
https://doaj.org/article/c2b8baefb8414a9487f153efe10b0137