Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Laura E Sperling"'
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36683 (2012)
The enzyme acetylcholinesterase (AChE) terminates synaptic transmission at cholinergic synapses by hydrolyzing the neurotransmitter acetylcholine, but can also exert 'non-classical', morpho-regulatory effects on developing neurons such as stimulation
Externí odkaz:
https://doaj.org/article/df78e636e1b448ebbf399b2d2023cbd7
Publikováno v:
Biologie in unserer Zeit. 50:318-330
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7152d34b10d981621ddfe666b98dbf2
https://doi.org/10.1002/biuz.202010714
https://doi.org/10.1002/biuz.202010714
Autor:
Cristian Euzebio Teixeira, Laura Gonçalves Pozzobon, Tais Malysz, Laura E. Sperling, Patricia Pranke
Publikováno v:
Chemico-biological interactions. 348
A promising alternative to conventional nerve grafting is the use of artificial grafts made from biodegradable and biocompatible materials and support cells. The aim of this study has been to produce a biodegradable nerve conduit and investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abe0f9f2fdfaa69e18b25cf3ae55ada
https://pubmed.ncbi.nlm.nih.gov/34450165
https://pubmed.ncbi.nlm.nih.gov/34450165
Publikováno v:
Tissue engineering. Part B, Reviews. 27(4)
Spinal cord injury (SCI) affects the central nervous system (CNS) and there is currently no treatment with the potential for rehabilitation. Although several clinical treatments have been developed, they are still at an early stage and have not shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718cae201a65dd9192cefd473dfb3c62
https://pubmed.ncbi.nlm.nih.gov/33135599
https://pubmed.ncbi.nlm.nih.gov/33135599
Autor:
Johannes L. Frieß, Laura E. Sperling, Gopenath Thangaraj, Paul G. Layer, Astrid Vogel-Höpker, Janine Spieker
Publikováno v:
International immunopharmacology. 83
There is ample evidence that cholinergic actions affect the health status of bones in vertebrates including man. Nicotine smoking, but also exposure to pesticides or medical drugs point to the significance of cholinergic effects on bone status, as re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d318b199983c1c5f6c1529a2f0f5092f
https://pubmed.ncbi.nlm.nih.gov/32208165
https://pubmed.ncbi.nlm.nih.gov/32208165
Autor:
Cristian Euzebio Teixeira, Ágata Paim, Roland A. Fleck, Laura E. Sperling, Bruno Alcântara, Gema Vizcay-Barrena, Patricia Pranke, Karina Pires Reis
Publikováno v:
Regenerative Medicine. 13:785-801
Aim: Scaffolds are a promising approach for spinal cord injury (SCI) treatment. FGF-2 is involved in tissue repair but is easily degradable and presents collateral effects in systemic administration. In order to address the stability issue and avoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb3acb3d79f6c3e63a2d73883f0fbc3
https://doi.org/10.2217/rme-2018-0060
https://doi.org/10.2217/rme-2018-0060
Autor:
Patricia Helena Lucas Pranke, Laura E. Sperling, Carolina Saibro Girardi, Karina P. Reis, Laura Gonçalves Pozzobon
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:1333-1345
Engineering neural tissue by combining biodegradable materials, cells and growth factors is a promising strategy for the treatment of central and peripheral nervous system injuries. In this study, neural differentiation of mouse embryonic stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e92d1ba6d5deb6bffa8053866ac5791d
https://doi.org/10.1002/jbm.a.36012
https://doi.org/10.1002/jbm.a.36012
Autor:
Cristian Euzebio Teixeira, Laura E. Sperling, Marcelo Garrido dos Santos, Carlos Alexandre Netto, Eduardo Luis Konrath, Fabrício do Couto Nicola, Gabriele Gulielmin Didó, Karina Pires Reis, Patricia Pranke
Publikováno v:
Brain research. 1724
Spinal cord injury (SCI) is a medical condition that currently lacks effective treatment. Galantamine is a reversible, competitive acetylcholinesterase inhibitor, used to treat patients with Alzheimeŕs disease. It has been demonstrated that galantam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12af58a00c64e8b194cd4b7bdba187e2
https://pubmed.ncbi.nlm.nih.gov/31472112
https://pubmed.ncbi.nlm.nih.gov/31472112
Autor:
Patricia Pranke, Daikelly B. Iglesias, Cesar Liberato Petzhold, Janine Machado, Jéssica F. T. C. Petry, Laura E. Sperling, Pedro C. Chagastelles, Andrea G. Galuppo, Douglas Gamba, Joachim H. Wendorff
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:424-432
The aim of the study has been to evaluate the morphology, proliferation, and pluripotency maintenance of mouse embryonic stem cells (mESCs) cultivated on poly(lactic-co-glycolic acid) scaffolds. The scaffolds were hydrolyzed with NaOH (treated) and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::786ed8faa1e3c4a1da5baa572ff3659b
https://doi.org/10.1002/jbm.a.35916
https://doi.org/10.1002/jbm.a.35916
Publikováno v:
Drug Discovery Today. 21:1243-1256
Whereas highly porous scaffolds composed of electrospun nanofibers can mimick major features of the extracellular matrix in tissue engineering, they lack the ability to incorporate and release biocompounds (drugs, growth factors) safely in a controll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c110c574f812b16b945874f16428d87
https://doi.org/10.1016/j.drudis.2016.04.024
https://doi.org/10.1016/j.drudis.2016.04.024