Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Laura E Niklason"'
Autor:
Edward X Han, Juan Wang, Mehmet Kural, Bo Jiang, Katherine L Leiby, Nazar Chowdhury, George Tellides, Richard G Kibbey, Jeffrey H Lawson, Laura E Niklason
Publikováno v:
Journal of Tissue Engineering, Vol 12 (2021)
Transplantation of pancreatic islets has been shown to be effective, in some patients, for the long-term treatment of type 1 diabetes. However, transplantation of islets into either the portal vein or the subcutaneous space can be limited by insuffic
Externí odkaz:
https://doaj.org/article/03ac6172dbe145e3a43e9858e35ca716
Autor:
Neal G Ravindra, Mia Madel Alfajaro, Victor Gasque, Nicholas C Huston, Han Wan, Klara Szigeti-Buck, Yuki Yasumoto, Allison M Greaney, Victoria Habet, Ryan D Chow, Jennifer S Chen, Jin Wei, Renata B Filler, Bao Wang, Guilin Wang, Laura E Niklason, Ruth R Montgomery, Stephanie C Eisenbarth, Sidi Chen, Adam Williams, Akiko Iwasaki, Tamas L Horvath, Ellen F Foxman, Richard W Pierce, Anna Marie Pyle, David van Dijk, Craig B Wilen
Publikováno v:
PLoS Biology, Vol 19, Iss 3, p e3001143 (2021)
There are currently limited Food and Drug Administration (FDA)-approved drugs and vaccines for the treatment or prevention of Coronavirus Disease 2019 (COVID-19). Enhanced understanding of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Externí odkaz:
https://doaj.org/article/953d8b25aa2b462bb1a23148fd6012d7
Autor:
Mehmet H. Kural, Umidahan Djakbarova, Bilal Cakir, Yoshiaki Tanaka, Emily T. Chan, Valeria I. Arteaga Muniz, Yasaman Madraki, Hong Qian, Jinkyu Park, Lorenzo R. Sewanan, In-Hyun Park, Laura E. Niklason, Comert Kural
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-11 (2024)
Abstract The transmembrane death receptor Fas transduces apoptotic signals upon binding its ligand, FasL. Although Fas is highly expressed in cancer cells, insufficient cell surface Fas expression desensitizes cancer cells to Fas-induced apoptosis. H
Externí odkaz:
https://doaj.org/article/544a7a26c62646bdaf6e0dc321de4417
Autor:
Katherine L. Leiby, Yifan Yuan, Ronald Ng, Micha Sam Brickman Raredon, Taylor S. Adams, Pavlina Baevova, Allison M. Greaney, Karen K. Hirschi, Stuart G. Campbell, Naftali Kaminski, Erica L. Herzog, Laura E. Niklason
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Engineered whole lungs may one day expand therapeutic options for patients with end-stage lung disease. However, the feasibility of ex vivo lung regeneration remains limited by the inability to recapitulate mature, functional alveolar epithe
Externí odkaz:
https://doaj.org/article/343c803588cf4335a13da17cd8eca48c
Autor:
Oleksandr Sokolov, Vasyl Shaprynskyi, Oleh Skupyy, Oleksandr Stanko, Serhii Yurets, Yuliya Yurkova, Laura E. Niklason
Publikováno v:
The Lancet Regional Health. Europe, Vol 29, Iss , Pp 100650- (2023)
Externí odkaz:
https://doaj.org/article/a4564ff1eae34110998a17f05196458e
Autor:
Allison Marie Greaney, Micha Sam Brickman Raredon, Maria P. Kochugaeva, Laura E. Niklason, Andre Levchenko
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106175- (2023)
Summary: Despite much concerted effort to better understand severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral infection, relatively little is known about the dynamics of early viral entry and infection in the airway. Here we analyzed
Externí odkaz:
https://doaj.org/article/e76d935e39d34605bd7248a4a67b9e0f
Autor:
Allison M. Greaney, Abhay B. Ramachandra, Yifan Yuan, Arina Korneva, Jay D. Humphrey, Laura E. Niklason
Publikováno v:
Biomaterials and Biosystems, Vol 9, Iss , Pp 100074- (2023)
Tracheal replacement using tissue engineering technologies offers great potential to improve previously intractable clinical interventions, and interest in this area has increased in recent years. Many engineered airway constructs currently rely on d
Externí odkaz:
https://doaj.org/article/ff6ce22210604e1da76d7a727f8cbca0
Autor:
Tomasz Jakimowicz, Stanislaw Przywara, Jakub Turek, Alison Pilgrim, Michal Macech, Norbert Zapotoczny, Tomasz Zubilewicz, Jeffrey H. Lawson, Laura E. Niklason
Publikováno v:
EJVES Vascular Forum, Vol 54, Iss , Pp 58-63 (2022)
Objective: Patients with end stage renal failure who require haemodialysis suffer morbidity and mortality due to vascular access. Bioengineered human acellular vessels (HAVs) may provide a haemodialysis access option with fewer complications than oth
Externí odkaz:
https://doaj.org/article/f4303b349841405eac08cc2a9b00cf56
Autor:
Juan Wang, PhD, Shelby K.F. Blalock, BS, Garyn S. Levitan, BS, Heather L. Prichard, PhD, Laura E. Niklason, MD, PhD, Robert D. Kirkton, PhD
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100120- (2023)
Objective: Synthetic expanded polytetrafluoroethylene (ePTFE) grafts are known to be susceptible to bacterial infection. Results from preclinical and clinical studies of bioengineered human acellular vessels (HAVs) have shown relatively low rates of
Externí odkaz:
https://doaj.org/article/e0b512fc3d894edb9a772e6e3fb74e7c
Autor:
Piotr Gutowski, MD, PhD, Malgorzata Guziewicz, MD, PhD, Marek Ilzecki, MD, PhD, Arkadiusz Kazimierczak, MD, PhD, Jeffrey H. Lawson, MD, PhD, Heather L. Prichard, PhD, Stanislaw Przywara, MD, PhD, Rabih Samad, MD, PhD, William Tente, MS, Jakub Turek, MD, Wojcieh Witkiewicz, MD, PhD, Norbert Zapotoczny, MD, Tomaz Zubilewicz, MD, PhD, Laura E. Niklason, MD, PhD
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100092- (2023)
Objective: The human acellular vessel (HAV) was evaluated for surgical bypass in a phase II study. The primary results at 24 months after implantation have been reported, and the patients will be evaluated for ≤10 years. Methods: In the present rep
Externí odkaz:
https://doaj.org/article/7240c3fbd0244a0c826ab872a7c32cd1