Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Laura E Kuil"'
Autor:
Laura E Kuil, Katherine C MacKenzie, Clara S Tang, Jonathan D Windster, Thuy Linh Le, Anwarul Karim, Bianca M de Graaf, Robert van der Helm, Yolande van Bever, Cornelius E J Sloots, Conny Meeussen, Dick Tibboel, Annelies de Klein, René M H Wijnen, Jeanne Amiel, Stanislas Lyonnet, Maria-Mercè Garcia-Barcelo, Paul K H Tam, Maria M Alves, Alice S Brooks, Robert M W Hofstra, Erwin Brosens
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009698 (2021)
Hirschsprung disease (HSCR) is a complex genetic disease characterized by absence of ganglia in the intestine. HSCR etiology can be explained by a unique combination of genetic alterations: rare coding variants, predisposing haplotypes and Copy Numbe
Externí odkaz:
https://doaj.org/article/1c07ad4d76c24f9488439c5f30f264c2
Autor:
Laura E Kuil, Nynke Oosterhof, Giuliano Ferrero, Tereza Mikulášová, Martina Hason, Jordy Dekker, Mireia Rovira, Herma C van der Linde, Paulina MH van Strien, Emma de Pater, Gerben Schaaf, Erik MJ Bindels, Valerie Wittamer, Tjakko J van Ham
Publikováno v:
eLife, Vol 9 (2020)
Macrophages derive from multiple sources of hematopoietic progenitors. Most macrophages require colony-stimulating factor 1 receptor (CSF1R), but some macrophages persist in the absence of CSF1R. Here, we analyzed mpeg1:GFP–expressing macrophages i
Externí odkaz:
https://doaj.org/article/ab98d27251c647b7b6ce1d7183bfc961
Autor:
Sofia Kanatsou, Brenna C Fearey, Laura E Kuil, Paul J Lucassen, Anjanette P Harris, Jonathan R Seckl, Harm Krugers, Marian Joels
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145706 (2015)
Externí odkaz:
https://doaj.org/article/08405c5e15b648d291486091ed3ea1a2
Autor:
Sofia Kanatsou, Brenna C Fearey, Laura E Kuil, Paul J Lucassen, Anjanette P Harris, Jonathan R Seckl, Harm Krugers, Marian Joels
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142012 (2015)
Exposure to chronic stress is a risk factor for cognitive decline and psychopathology in genetically predisposed individuals. Preliminary evidence in humans suggests that mineralocorticoid receptors (MRs) may confer resilience to these stress-related
Externí odkaz:
https://doaj.org/article/4027a2398f1644a2946bf68ff9de58bb
Autor:
Laura E. Kuil, Naomi J.M. Kakiailatu, Jonathan D. Windster, Eric Bindels, Joke T.M. Zink, Gaby van der Zee, Robert M.W. Hofstra, Iain T. Shepherd, Veerle Melotte, Maria M. Alves
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107070- (2023)
Summary: The enteric nervous system (ENS) regulates many gastrointestinal functions including peristalsis, immune regulation and uptake of nutrients. Defects in the ENS can lead to severe enteric neuropathies such as Hirschsprung disease (HSCR). Zebr
Externí odkaz:
https://doaj.org/article/b7ec781be7a740e7809fef44bcc8fbf0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
The Enteric Nervous System (ENS) is a large network of enteric neurons and glia that regulates various processes in the gastrointestinal tract including motility, local blood flow, mucosal transport and secretion. The ENS is derived from stem cells c
Externí odkaz:
https://doaj.org/article/cec757a843634b019eec00d957c1dc9a
Autor:
Ping Zhang, Laura E. Kuil, Levi C.M. Buil, Stephan Freriks, Jos H. Beijnen, Olaf van Tellingen, Mark C. de Gooijer
PurposeBRAFV600-mutated melanoma brain metastases (MBMs) are responsive to BRAF inhibitors, but responses are generally less durable than those of extracranial metastases. We here tested the hypothesis that the drug efflux transporters P-glycoprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44fe07888360bd3a7e7b9d3d32c58226
https://doi.org/10.1101/2022.12.20.521202
https://doi.org/10.1101/2022.12.20.521202
Autor:
Almira Zada, Laura E. Kuil, Bianca M. de Graaf, Naomi Kakiailatu, Jonathan D. Windster, Alice S. Brooks, Marjon van Slegtenhorst, Barbara de Koning, René M. H. Wijnen, Veerle Melotte, Robert M. W. Hofstra, Erwin Brosens, Maria M. Alves
Publikováno v:
Frontiers in Cell and Developmental Biology, 10:901824. Frontiers Media S.A.
Frontiers in Cell and Developmental Biology, 10:901824. Frontiers Media SA
Frontiers in Cell and Developmental Biology, 10:901824. Frontiers Media SA
Background: Pediatric Intestinal Pseudo-obstruction (PIPO) is a congenital enteric disorder characterized by severe gastrointestinal (GI) dysmotility, without mechanical obstruction. Although several genes have been described to cause this disease, m
Autor:
Alice S. Brooks, Robert van der Helm, Bianca M. de Graaf, Erwin Brosens, Conny J.H.M. Meeussen, Laura E. Kuil, Robert M.W. Hofstra, Thuy Linh Le, Anwarul Karim, Annelies de Klein, Rene M. H. Wijnen, Cornelius E. J. Sloots, Paul K.H. Tam, Maria M. Alves, Yolande van Bever, Clara S. Tang, Maria-Mercè Garcia-Barceló, Jeanne Amiel, Jonathan D. Windster, Katherine C. MacKenzie, Dick Tibboel, Stanislas Lyonnet
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009698 (2021)
PLoS Genetics, 17(8):1009698. Public Library of Science
PLoS Genetics
PLoS Genetics, 17(8):1009698. Public Library of Science
PLoS Genetics
Hirschsprung disease (HSCR) is a complex genetic disease characterized by absence of ganglia in the intestine. HSCR etiology can be explained by a unique combination of genetic alterations: rare coding variants, predisposing haplotypes and Copy Numbe
Autor:
Julie Mazzolini, Jean-François Zagury, Dirk Sieger, Cédric Coulonges, Laura E. Kuil, Sigrid Le Clerc, Gregoire Morisse, Tjakko J. van Ham
Publikováno v:
Glia
GLIA, 68, 298-315. John Wiley & Sons Inc.
Glia, Wiley, 2019, 68 (2), pp.298-315. ⟨10.1002/glia.23717⟩
Mazzolini, J, Le Clerc, S, Morisse, G, Coulonges, C, Kuil, L E, van Ham, T J, Zagury, J-F & Sieger, D 2019, ' Gene expression profiling reveals a conserved microglia signature in larval zebrafish ', Glia . https://doi.org/10.1002/glia.23717
GLIA, 68, 298-315. John Wiley & Sons Inc.
Glia, Wiley, 2019, 68 (2), pp.298-315. ⟨10.1002/glia.23717⟩
Mazzolini, J, Le Clerc, S, Morisse, G, Coulonges, C, Kuil, L E, van Ham, T J, Zagury, J-F & Sieger, D 2019, ' Gene expression profiling reveals a conserved microglia signature in larval zebrafish ', Glia . https://doi.org/10.1002/glia.23717
Microglia are the resident macrophages of the brain. Over the past decade, our understanding of the function of these cells has significantly improved. Microglia do not only play important roles in the healthy brain but are involved in almost every b