Developing practical recommendations for drug-disease interactions in patients with hypertension

Autor: Kübra Özokcu, Maaike M. E. Diesveld, Suzan G. H. Gipmans, Laura E. J. Peeters, Bert-Jan van den Born, Sander D. Borgsteede

Publikováno v: Frontiers in Pharmacology, Vol 15 (2024)

Background:Hypertension, a significant risk factor for cardiovascular diseases, demands proactive management as cardiovascular diseases remain the leading cause of death worldwide. Reducing systolic and diastolic blood pressure levels below recommend

Externí odkaz: https://doaj.org/article/876fdfffad454550801f7caa916e0231

Sex Differences in Spironolactone and the Active Metabolite Canrenone Concentrations and Adherence

Autor: Laura E. J. Peeters, Leonardien K. Tjong, Wim J. R. Rietdijk, Teun van Gelder, Birgit C. P. Koch, Jorie Versmissen

Publikováno v: Biomedicines, Vol 10, Iss 1, p 137 (2022)

We aim to investigate sex differences in blood concentrations of spironolactone and the active metabolite canrenone in resistant hypertension patients. Furthermore, sex differences in adherence for spironolactone and other antihypertensive drugs (AHD

Externí odkaz: https://doaj.org/article/2dddb8dafd954967bc19ce084c2d9266

Introducing the importance and difficulties of a threestep approach to improve nonadherence to antihypertensive drugs

Autor: Irene M. van der Meer, Kathy Schoenmakers-Buis, Jorie Versmissen, Emma K. Massey, Laura E J Peeters, Teun van Gelder, Liset van Dijk, Birgit C. P. Koch, Jeroen B. van der Net

Publikováno v: Journal of Hypertension, 40(1), 189-193. LIPPINCOTT WILLIAMS & WILKINS
Journal of Hypertension, 40(1), 189-193. Lippincott Williams & Wilkins
Journal of Hypertension

Nonadherence to antihypertensive drugs is an important reason for not reaching blood pressure goals. A possible method to improve nonadherence involves three essential steps: Identification of nonadherent patients (step 1), determination of underlyin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b830d3e16837120fa0d4f1bda80ef99
https://pure.eur.nl/en/publications/351c78de-2e41-430a-b821-158f48115761

Development and Validation of a Dried Blood Spot Assay Using UHPLC-MS/MS to Identify and Quantify 12 Antihypertensive Drugs and 4 Active Metabolites: Clinical Needs and Analytical Limitations

Autor: Laura E. J. Peeters, Soma Bahmany, Tim Dekker, Aya Aliawi, Bart van Domburg, Jorie Versmissen, Birgit C. P. Koch

Publikováno v: Therapeutic Drug Monitoring, 44(4), 568-577. Lippincott Williams & Wilkins

PURPOSE: As nonadherence to antihypertensive drugs (AHDs) can increase the risk of cardiovascular events, hospitalization, and higher costs, there is a need for a reliable, objective, and easy method to assess nonadherence in patients. The dried bloo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1c63237dbe74326af2d69ccb5b9b1a
https://pure.eur.nl/en/publications/efee826a-e3fc-40db-8f62-bf8d3864629c

DiffErenCes in AntihypertenSive Drug Blood Levels in Patients with HypertensiON (DECISION): Protocol for a Prospective Observational Study Comparing Pharmacokinetics and Pharmacodynamics Between Young and Elderly Patients

Autor: Dimokrat, Hassan, Laura E J, Peeters, Birgit C P, Koch, Jorie, Versmissen

Publikováno v: High blood pressurecardiovascular prevention : the official journal of the Italian Society of Hypertension. 29(3)

Adequate controlled blood pressure decreases the risk of cardiovascular events. However, the elderly are more vulnerable and thereby more prone to side effects of antihypertensive drugs. A lack of pharmacokinetic and pharmacodynamic (PK/PD) studies i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c94dbe64b5da609d6f068e840e63ac1a
https://pubmed.ncbi.nlm.nih.gov/35175576