Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Laura E Gleeson"'
Autor:
Donal J Cox, Sarah A Connolly, Cilian Ó Maoldomhnaigh, Aenea AI Brugman, Olivia Sandby Thomas, Emily Duffin, Karl M Gogan, Oisin Ó Gallchobhair, Dearbhla M Murphy, Sinead A O'Rourke, Finbarr O'Connell, Parthiban Nadarajan, James J Phelan, Laura E Gleeson, Sharee A Basdeo, Joseph Keane
Publikováno v:
eLife, Vol 13 (2024)
Airway macrophages (AM) are the predominant immune cell in the lung and play a crucial role in preventing infection, making them a target for host directed therapy. Macrophage effector functions are associated with cellular metabolism. A knowledge ga
Externí odkaz:
https://doaj.org/article/9c3246ecbdeb45c6a9668ba8b1cd623a
Publikováno v:
Breathe, Vol 19, Iss 4 (2023)
Pleural tuberculosis (TB) is a common entity with similar epidemiological characteristics to pulmonary TB. It represents a spectrum of disease that can variably self-resolve or progress to TB empyema with severe sequelae such as chronic fibrothorax o
Externí odkaz:
https://doaj.org/article/4d435776ff18438f864c30afdaf6d56f
Autor:
David J. F. Smith, Jamilah Meghji, Mufaddal Moonim, Clare Ross, Patrizia Viola, Melissa Wickremasinghe, Laura E. Gleeson
Publikováno v:
Respirology Case Reports, Vol 11, Iss 11, Pp n/a-n/a (2023)
Abstract Here we describe three cases of sarcoidosis which were diagnosed following COVID infection. Treating clinicians should consider post‐COVID‐19 sarcoidosis in their differential, as it represents a potentially treatable cause of persistent
Externí odkaz:
https://doaj.org/article/d20f7f0931274aebb57edc4a4965bc08
Autor:
Laura E. Gleeson, Grant Waterer
Publikováno v:
Breathe, Vol 18, Iss 2 (2022)
Nontuberculous mycobacteria (NTM) pulmonary disease represents a significant clinical challenge with suboptimal therapy and increasing prevalence globally. Although clinical practice guidelines seek to standardise the approach to diagnosis and treatm
Externí odkaz:
https://doaj.org/article/00ce231f16634279b5379eaa48c5a24f
Autor:
Emer E. Hackett, Hugo Charles-Messance, Seónadh M. O’Leary, Laura E. Gleeson, Natalia Muñoz-Wolf, Sarah Case, Anna Wedderburn, Daniel G.W. Johnston, Michelle A. Williams, Alicia Smyth, Mireille Ouimet, Kathryn J. Moore, Ed C. Lavelle, Sinéad C. Corr, Stephen V. Gordon, Joseph Keane, Frederick J. Sheedy
Publikováno v:
Cell Reports, Vol 30, Iss 1, Pp 124-136.e4 (2020)
Summary: Increased glycolytic metabolism recently emerged as an essential process driving host defense against Mycobacterium tuberculosis (Mtb), but little is known about how this process is regulated during infection. Here, we observe repression of
Externí odkaz:
https://doaj.org/article/940d7725a10c42f3aa2a7e0bce32ab6d
Autor:
Éilis Dockry, Seónadh O'Leary, Laura E. Gleeson, Judith Lyons, Joseph Keane, Steven G. Gray, Derek G. Doherty
Publikováno v:
OncoImmunology, Vol 7, Iss 6 (2018)
Immunotherapies that target CD1d-restricted invariant NKT (iNKT) cells can prevent tumor growth in murine models but trials in humans have shown limited clinical efficacy. Here, we show that iNKT cells are depleted from blood and bronchial lavage sam
Externí odkaz:
https://doaj.org/article/1b6210d97c56454a9c0b0e1dda0867ba
Autor:
Laura E. Gleeson, Grant Waterer
Publikováno v:
Breathe (Sheffield, England). 18(2)
Nontuberculous mycobacteria (NTM) pulmonary disease represents a significant clinical challenge with suboptimal therapy and increasing prevalence globally. Although clinical practice guidelines seek to standardise the approach to diagnosis and treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85370ccacb93d730af6c0942c1a9baef
https://pubmed.ncbi.nlm.nih.gov/36337137
https://pubmed.ncbi.nlm.nih.gov/36337137
Autor:
Hugo Charles-Messance, Anna Wedderburn, Emer E. Hackett, Ed C. Lavelle, Mireille Ouimet, Joseph Keane, Natalia Muñoz-Wolf, Laura E. Gleeson, Frederick J. Sheedy, Seónadh O'Leary, Kathryn J. Moore, Daniel G.W. Johnston, Michelle A. Williams, Sinéad C. Corr, Sarah Case, Stephen V. Gordon, Alicia Smyth
Publikováno v:
Cell Reports, Vol 30, Iss 1, Pp 124-136.e4 (2020)
Cell Rep
Cell Rep
Summary: Increased glycolytic metabolism recently emerged as an essential process driving host defense against Mycobacterium tuberculosis (Mtb), but little is known about how this process is regulated during infection. Here, we observe repression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8629cd934a423927a68b9b180167aca1
http://www.sciencedirect.com/science/article/pii/S2211124719316651
http://www.sciencedirect.com/science/article/pii/S2211124719316651
Publikováno v:
British Journal of Nutrition
The British Journal of Nutrition
The British Journal of Nutrition
As COVID-19 continues to spread worldwide, severe disease and mortality have been observed in obese patients. We discuss how obesity and obesity-associated factors such as ‘meta-flammation’, dietary fat intake and paradoxical suppression of the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d161b40a3d4b15212979ce24811cf53