Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Laura E Collins"'
Autor:
Laura E Collins, Joseph eDeCourcey, Mariana eSoleda di Luca, Keith D Rochfort, Christine E Loscher
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Dendritic cells (DCs) provide an essential link between innate and adaptive immunity. At the site of infection, antigens recognised by DCs via pattern-recognition receptors such as Toll like receptors (TLR), initiate a specific immune response. Depen
Externí odkaz:
https://doaj.org/article/b5c4aef95b234ec8be351f4d6b03ef25
Publikováno v:
Frontiers in Immunology, Vol 5 (2015)
The role of dendritic cells (DCs) in directing the immune response is due in part to their capacity to produce a range of cytokines. Importantly, DCs are a source of cytokines which can promote T cell survival and T helper cell differentiation. While
Externí odkaz:
https://doaj.org/article/deb787c865754484b1f53e253cef29ab
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101815 (2014)
Blood-brain barrier (BBB) dysfunction is an integral feature of neurological disorders and involves the action of multiple proinflammatory cytokines on the microvascular endothelial cells lining cerebral capillaries. There is still however, considera
Externí odkaz:
https://doaj.org/article/0102f18804ab496c918377be783099cb
Autor:
Laura E Collins, Linda Troeberg
Publikováno v:
Journal of Leukocyte Biology. 105:81-92
Heparan sulfate is found on the surface of most cell types, as well as in basement membranes and extracellular matrices. Its strong anionic properties and highly variable structure enable this glycosaminoglycan to provide binding sites for numerous p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7124cc37e38033f208e07db44f24343d
https://doi.org/10.1002/jlb.3ru0618-246r
https://doi.org/10.1002/jlb.3ru0618-246r
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(5)
The metalloproteinase ADAM17 plays a pivotal role in initiating inflammation by releasing TNF from its precursor. Prolonged TNF release causes many chronic inflammatory diseases, indicating that tight regulation of ADAM17 activity is essential for re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4141e8a9dad03206a799214688f640
https://pubmed.ncbi.nlm.nih.gov/30659107
https://pubmed.ncbi.nlm.nih.gov/30659107
Surface layer proteins isolated from Clostridium difficile induce clearance responses in macrophages
Autor:
Mary J. O'Connell, Henry J. Windle, Izabela Marszalowska, Dermot Kelleher, Christine E. Loscher, Maja Kristek, Mark Lynch, Keith D. Rochfort, Laura E. Collins
Publikováno v:
Microbes and Infection. 16:391-400
Clostridium difficile is the leading cause of hospital-acquired diarrhoea worldwide, and if the bacterium is not cleared effectively it can pose a risk of recurrent infections and complications such as colitis, sepsis and death. In this study we demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7df66eb2e59ed4481818611648fda4
https://doi.org/10.1016/j.micinf.2014.02.001
https://doi.org/10.1016/j.micinf.2014.02.001
Publikováno v:
Journal of neurochemistry. 136(3)
The co-involvement of tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6) during blood-brain barrier (BBB) injury has been reported in various models of neuroinflammation, although the precise functional interplay between these archetypal pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cba1782922265e4b9c51f628efdc5b8
https://pubmed.ncbi.nlm.nih.gov/26499872
https://pubmed.ncbi.nlm.nih.gov/26499872
The regulatory interplay between laminar shear stress and proinflammatory cytokines during homeostatic maintenance of the brain microvascular endothelium is largely undefined. We hypothesized that laminar shear could counteract the injurious actions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3341f6170f76ca6a2f2907e1cfff3285
https://europepmc.org/articles/PMC4640321/
https://europepmc.org/articles/PMC4640321/
Autor:
L Brennan, Christine E. Loscher, Gabriele Gross, Laura E. Collins, J Aarbiou, N Ben Larbi, F Fischer, E. van Tol, Tim T. Lambers
Publikováno v:
The FASEB Journal. 29
Objectives: Type 1 Diabetes is characterized by progressive autoimmune destruction of pancreatic β-cells. The aim of this study was to assess whether extensively hydrolyzed casein might interfere w...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d512302e8c39a7cb12ea898ac9eed9cb
https://doi.org/10.1096/fasebj.29.1_supplement.599.4
https://doi.org/10.1096/fasebj.29.1_supplement.599.4
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology, Vol 6 (2015)
Dendritic cells (DCs) provide an essential link between innate and adaptive immunity. At the site of infection, antigens recognized by DCs via pattern-recognition receptors, such as Toll-like receptors (TLRs), initiate a specific immune response. Dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5798257d0aa82b0bf2c8c823f34b4674