Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Laura Doepker"'
Autor:
Zak A. Yaffe, Shilei Ding, Kevin Sung, Vrasha Chohan, Lorie Marchitto, Laura Doepker, Duncan Ralph, Ruth Nduati, Frederick A. Matsen, IV, Andrés Finzi, Julie Overbaugh
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106762- (2023)
Summary: Human natural history and vaccine studies support a protective role of antibody dependent cellular cytotoxicity (ADCC) activity against many infectious diseases. One setting where this has consistently been observed is in HIV-1 vertical tran
Externí odkaz:
https://doaj.org/article/4f4bf47f474c4fb0af7d504dc24f86a5
Autor:
Cassandra Simonich, Mackenzie M. Shipley, Laura Doepker, Theodore Gobillot, Meghan Garrett, Evan M. Cale, Brianna Hennessy, Hannah Itell, Vrasha Chohan, Nicole Doria-Rose, Ruth Nduati, Julie Overbaugh
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 6, Pp 100314- (2021)
Summary: Increasing evidence suggests infants develop unique neutralizing antibody (nAb) responses to HIV compared to adults. Here, we dissected the nAb response of an infant whose virus is in clinical trials as a vaccine immunogen, with a goal of ch
Externí odkaz:
https://doaj.org/article/66a65a226a7c4853b5cf1d271e5d0074
Autor:
Cassandra A. Simonich, Laura Doepker, Duncan Ralph, James A. Williams, Amrit Dhar, Zak Yaffe, Lauren Gentles, Christopher T. Small, Brian Oliver, Vladimir Vigdorovich, Vidya Mangala Prasad, Ruth Nduati, D. Noah Sather, Kelly K. Lee, Frederick A. Matsen IV, Julie Overbaugh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Development of broadly neutralizing antibodies (bnAb) against HIV-1 in infected adults is a multi-step process unachievable by current vaccine approaches. Here the authors reconstruct the ontogeny of an infant bnAb, which develops in fewer steps, and
Externí odkaz:
https://doaj.org/article/5b8e79bde5ec414da4937e1e8049ac81