Hypoxia Impairs Initial Outgrowth of Endothelial Colony Forming Cells and Reduces Their Proliferative and Sprouting Potential

Autor: Michiel van Wijhe, Henk J. Broxterman, Victor W.M. van Hinsbergh, Dimitar Tasev, Pieter Koolwijk, Laura Dekker-Vroling

Publikováno v: Frontiers in Medicine, Vol 5 (2018)
Frontiers in medicine, 5:356. Frontiers Media S.A.
Frontiers in Medicine
Tasev, D, Dekker-Vroling, L, van Wijhe, M, Broxterman, H J, Koolwijk, P & van Hinsbergh, V W M 2018, ' Hypoxia Impairs Initial Outgrowth of Endothelial Colony Forming Cells and Reduces Their Proliferative and Sprouting Potential ', Frontiers in medicine, vol. 5, 356 . https://doi.org/10.3389/fmed.2018.00356

Vascular homeostasis and regeneration in ischemic tissue relies on intrinsic competence of the tissue to rapidly recruit endothelial cells for vascularization. The mononuclear cell (MNC) fraction of blood contains circulating progenitors committed to

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https://www.frontiersin.org/article/10.3389/fmed.2018.00356/full